[1]丁伟佳,陈 茵,郑伟基,等. 不同皮肤移植方法在大面积烧伤瘢痕修复中的效果比较[J].中国美容医学,2018,(03):36-38.
 DING Wei-jia,CHEN Yin,ZHENG Wei-ji,et al. Comparison of the Effect of Different Skin Grafting Methods in Scar Repair of Large Area Burns[J].Medical Aesthetics and Beauty,2018,(03):36-38.
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 不同皮肤移植方法在大面积烧伤瘢痕修复中的效果比较
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《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2018年03期
页码:
36-38
栏目:
出版日期:
2018-04-10

文章信息/Info

Title:
 Comparison of the Effect of Different Skin Grafting Methods in Scar Repair of Large Area Burns
文章编号:
1008-6455(2018)03-0036
作者:
 丁伟佳陈 茵郑伟基何 穆
Author(s):
 DING Wei-jiaCHEN YinZHENG Wei-jiHE Mu
关键词:
 [关键词]复合皮移植术大面积烧伤瘢痕修复CD46创面愈合
Keywords:
 Key words: composite skin grafting large area burns scar repair CD46 wound healing
分类号:
R622
文献标志码:
A
摘要:

[摘要]目的:探讨复合皮移植术与反复切取后躯干瘢痕皮修复对大面积烧伤瘢痕整形患者免疫耐受、创面愈合情况的影
响。方法:选取于本院烧伤科就诊或住院治疗的96例大面积烧伤瘢痕整形患者,按照随机数字表法分为2组,对照组46例患
者采用反复切取后躯干瘢痕皮方法进行治疗,观察组50例患者采取复合皮移植术治疗,比较两组患者治疗后血管紧张素Ⅱ
(AngⅡ)及CD46水平、创面愈合率、创面周围炎症反应情况。结果:治疗后两组患者血清AngⅡ、CD46水平与治疗前相比
均下降(P <0.05),观察组下降较对照组更为明显,组间比较差异有统计学意义(P <0.05);观察组患者治疗后14d、21d、
28d、35d创面愈合率及创面周围炎症反应评分均高于对照组,差异有统计学意义(P <0.05);与对照组相比,观察组患者平
均创面愈合时间及创面皮肤血运恢复时间更短,术后并发症发生率更低(P <0.05)。结论:复合皮移植术与常规皮肤移植方
法相比能够降低大面积烧伤瘢痕整形患者皮肤移植后的排异反应,加速创面愈合并减少术后并发症,值得临床推广应用。

Abstract:

Abstract: Objective To investigate the effects of skin grafting combined with skin grafting on the immune tolerance and
wound healing in patients with scar burn and plastic surgery. Methods 96 cases of patients with large-scale burn scar-shaped
were selected in this study. All patients were randomly divided into two groups.46 patients in the control group were treated
by repeatedly taking the scar skin after torso treatment, and 50 patients in the observation group were treated with compound
skin grafts. The serum level of angiotensin Ⅱ (Ang Ⅱ), serum level of CD46, wound healing rate and inflammation around
the wound were compared between two groups after treatment. Results After treatment, the serum level of Ang Ⅱ and CD46
in both groups were decreased(P <0.05), and the observation group was more obvious than the control group(P <0.05). The
wound healing rate and inflammation response score around the wound of 14d, 21d, 28d, 35d in the observation group were
higher than those of the control group, and the difference was statistically significant(P <0.05). Compared with the control
group, the average wound healing time and the wound skin blood transport recovery time were shorter in the observation
group, and the incidence of postoperative complications was lower(P <0.05). Conclusion Compared with conventional skin
grafting, composite skin grafting can reduce the rate of rejection after skin grafting, and accelerate wound healing and reduce
postoperative complications, which is worthy of clinical application.

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更新日期/Last Update: 2018-05-24