[1]李红敏,吉 津,闵仲生,等.红蓝光联合胶原贴敷料治疗玫瑰痤疮疗效观察[J].中国美容医学,2018,(09):37-39.
　LI Hong-min,JI Jin,MIN Zhong-sheng,et al.Clinical Efficacy of Blue-red LED Phototherapy Combined with Collagen Dressing for Rosacea[J].Medical Aesthetics and Beauty,2018,(09):37-39.
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红蓝光联合胶原贴敷料治疗玫瑰痤疮疗效观察
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《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2018年09期
页码:
37-39
栏目:
出版日期:
2018-10-10

文章信息/Info

Title:
Clinical Efficacy of Blue-red LED Phototherapy Combined with Collagen Dressing for Rosacea
文章编号:
1008-6455（2018）08-0037-03
作者:
李红敏; 吉 津; 闵仲生; 谭 城
Author(s):
LI Hong-min; JI Jin; MIN Zhong-sheng; TAN Cheng
关键词:
[关键词]红蓝光; 胶原贴敷料; 光疗; 玫瑰痤疮; 疗效
Keywords:
Key words: blue-red LED phototherapy;  collagen dressing;  phototherapy;  rosacea;  clinical efficacy
分类号:
R758.73+3
文献标志码:
B
摘要:

[摘要]目的：观察红蓝光联合胶原贴敷料治疗玫瑰痤疮的疗效及安全性。方法：选取2015年7月-2017年7月笔者医院门诊就
诊的30例Ⅰ型及Ⅱ型玫瑰痤疮患者为研究对象。给予口服甲硝唑片，外用皮脂搽剂，并予红蓝光联合胶原贴敷料治疗，疗程为
4周。结果：治疗4周后，总有效率为66.67%。红蓝光联合胶原贴敷料治疗可减轻玫瑰痤疮红斑（t =9.31，P ＜0.001）、皮肤敏
感（t =4.17，P＜0.001），减少丘疹脓疱数目（t =6.32，P＜0.001），有效缓解玫瑰痤疮的总体病情（t =8.25，P＜0.001）。
但对毛细血管扩张的改善效果欠佳（t =0.35，P ＞0.05），未见严重不良反应。结论：红蓝光联合胶原贴敷料治疗玫瑰痤疮
安全、有效，可缓解红斑、皮肤敏感，减少丘疹、脓疱，但对毛细血管扩张的效果欠佳。

Abstract:
Abstract: Objective To evaluate the efficacy and safety of combined therapy of blue-red LED phototherapy and collagen
dressing. Methods Thirty patients with rosacea were recruited. Metronidazole tablets and sebum liniment were used for
all patients. In addition to the above treatments, combined therapy of blue-red LED phototherapy and collagen dressing
werealsoapplied to the participants. The duration of treatment was four weeks. Results The combined therapy was effective for
overall severity (t =8.25,P ＜0.001),flushing (t =9.31,P ＜0.001),skin sensitivity (t =4.17, P ＜0.001), papules and pustules (t =6.32,
P ＜0.001). However, treatment effect for telangiectasia was not statistically significant(t =0.35, P ＞0.05). The effective rate of
this therapy was 66.67%. No severe adverse event was observed in these participants. Conclusion Combined therapy of bluered
LED phototherapy and collagen dressing were safe and efficacious for rosacea, they could improve flushing, skin sensitivity,
papules and pustules, but showed no statistical efficacy for telangiectasia.

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更新日期/Last Update: 2018-10-31