[1]左 飞.鼠神经生长因子联合皮瓣修复术治疗电烧伤创面[J].中国美容医学,2018,(09):52-55.
　ZUO Fei.Treatment of Electric Burn Wounds with Rat Nerve Growth Factor Combined with Skin Flap Repair[J].Medical Aesthetics and Beauty,2018,(09):52-55.
点击复制

鼠神经生长因子联合皮瓣修复术治疗电烧伤创面
()
分享到：

《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2018年09期
页码:
52-55
栏目:
出版日期:
2018-10-10

文章信息/Info

Title:
Treatment of Electric Burn Wounds with Rat Nerve Growth Factor Combined with Skin Flap Repair
文章编号:
1008-6455（2018）09-0052-04
作者:
左 飞
Author(s):
ZUO Fei
关键词:
[关键词]电烧伤; 皮瓣修复术; 鼠神经生长因子; 神经传导速度
Keywords:
Key words: electric burn;  skin flap repair;  rat nerve growth factor;  nerve conduction velocity
分类号:
R622
文献标志码:
A
摘要:
[摘要]目的：探讨鼠神经生长因子联合皮瓣修复术治疗电烧伤创面的临床效果。方法：选择2013年8月-2017年8月笔者医院
就诊的90例电烧伤患者为研究对象，通过随机数表法分为观察组（n =46）和对照组（n =44）。对照组给予皮瓣修复术治疗，
术后给予抗生素、维生素B12常规治疗；观察组在对照组基础上，联合鼠神经生长因子治疗。比较两组围手术期情况，治疗
前、后神经传导速度的变化，感觉、运动功能改善情况及不良反应发生情况。结果：观察组创面愈合时间、住院时间、手
术至出院时间及创面感染发生率均明显少于对照组，差异有统计学意义（P ＜0.05）。治疗后半年，两组感觉神经传导速度
（Sensory nerve conduction velocity，SCV）、运动神经传导速度（Motor nerve conduction velocity，MCV）均较治
疗前明显改善，观察组SCV、MCV均明显高于对照组[（43.84±3.18）m/s vs（39.05±3.02）m/s，（57.30±4.69）m/s vs
（50.34±4.22）m/s]，差异有统计学意义（P ＜0.05）。观察组感觉功能优良率及运动功能优良率均优于对照组（89.13%
vs 70.45%，86.96% vs 68.18%），差异有统计学意义（P ＜0.05）。两组不良反应总发生率分别为8.70%和4.55%，组间比较
差异无统计学意义（P ＞0.05）。结论：电烧伤创面应用鼠神经生长因子联合皮瓣修复术治疗效果显著，可有效修复神经损
伤，促进肢体感觉、运动功能恢复，且不良反应少，用药安全性高。
Abstract:

Abstract: Objective To study the curative efficacy of rat nerve growth factor combined with skin flap repair in treatment of electric
burn wounds. Methods 90 patients of electric burn who received therapy from August 2013 to August 2017 in our hospital were
selected as research objects, according to random number table, they were divided into the observation group (n =46) and the control
group (n =46). The control group was treated with skin flap repair, and antibiotics and vitamin B12 were given routine treatment
after operation. The observation group was combined with mouse nerve growth factor therapy on the basis of the control group. The
perioperative conditions of the two groups were compared, and the changes of nerve conduction velocity before and after treatment,
the sensation, motor function and adverse reactions were compared. Results The wound healing time, hospitalization time, operation
to discharge time and wound infection rate in the observation group were significantly less than those in the control group, the
differences were statistically significant(P ＜0.05). After half a year, sensory nerve conduction velocity (SCV) and motor nerve
conduction velocity (MCV) in the two groups were significantly improved compared with those before treatment,and the
SCV and MCV in the observation group were significantly higher than those in the control group[（43.84±3.18）m/s vs
（39.05±3.02）m/s,（57.30±4.69）m/s vs（50.34±4.22）m/s], the difference were statistical significance(P ＜0.05). The
excellent rate of sensory function and motor function in the observation group were superior to those in the control group
(89.13% vs 70.45%, 86.96% vs 68.18%), the differences were statistically significant(P ＜0.05). The total incidence of adverse
reactions in the two groups was 8.70% and 4.55% respectively, and there was no significant difference(P ＞0.05). Conclusion
Rat nerve growth factor combined with skin flap repair is well for electric burn，which can effectively repair nerve injury,
promote limb sensory and motor function recovery, and has fewer adverse reactions and high safety.

相似文献/References:

[1] 刘孝国,吴其科,徐 周. 活血祛瘀类中药汤剂在手部软组织缺损皮瓣修复术后的应用研究[J].中国美容医学,2021,(4):74.
　 LIU Xiao-guo,WU Qi-ke,XU Zhou. Application of Traditional Chinese Medicine Decoction for Activating Blood andRemoving Stasis on Hand Soft Tissue Defect after Skin Flap Repair[J].Medical Aesthetics and Beauty,2021,(09):74.
[2] 丁红梅,孙建华,姜春庭,等. 个性化护理在皮瓣修复大面积头皮缺损围手术期的应用效果评价[J].中国美容医学,2021,(7):158.
　 DING Hong-mei,SUN Jian-hua,JIANG Chun-ting,et al. Evaluation of Individualized Nursing in the Perioperative Period of Large Area Scalp Defect Skin Flap Repair[J].Medical Aesthetics and Beauty,2021,(09):158.
[3]刘 涛,唐 俊,张西蓉,等.皮肤牵张器在下肢骨折后皮肤软组织缺损创面修复中的应用[J].中国美容医学,2022,(7):41.
　LIU Tao,TANG Jun,ZHANG Xirong,et al.Application of Skin Stretching Device in the Repair of Skin Soft Tissue Defects after Lower Limbs Fractures[J].Medical Aesthetics and Beauty,2022,(09):41.
[4]杨 倩,金 杨,李相龙,等.“6E”模式下健康教育在四肢软组织缺损皮瓣修复中的应用[J].中国美容医学,2023,(5):175.
　YANG Qian,JIN Yang,LI Xianglong,et al.Application of Health Education Under 6E Mode in Patients Undergoing Flap Repair of Soft Tissue Defects?/html>[J].Medical Aesthetics and Beauty,2023,(09):175.
[5]周 靳,彭友林,王 强,等.个性化皮瓣修复臀骶周围深度压疮疗效观察[J].中国美容医学,2023,(6):35.[doi:10.15909/j.cnki.cn61-1347/r.005728]
　ZHOU Jin,PENG Youlin,WANG Qiang,et al.Observation on the Curative Effect of Personalized Skin Flap for Repairing Deep Pressure Sore Around Gluteal Sacrum[J].Medical Aesthetics and Beauty,2023,(09):35.[doi:10.15909/j.cnki.cn61-1347/r.005728]

更新日期/Last Update: 2018-10-31