[1]侯 勇,刘 唯. 调Q激光联合氨甲环酸巴布剂治疗面部黄褐斑疗效研究[J].中国美容医学,2019,(01):76-78.
　HOU Yong,LIU Wei. Study on the Efficacy of Q-switched Laser Combined with Tranexamic AcidCataplasm in the Treatment of Facial Chloasma[J].Medical Aesthetics and Beauty,2019,(01):76-78.
点击复制

 调Q激光联合氨甲环酸巴布剂治疗面部黄褐斑疗效研究
()
分享到：

《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2019年01期
页码:
76-78
栏目:
出版日期:
2019-01-15

文章信息/Info

Title:
 Study on the Efficacy of Q-switched Laser Combined with Tranexamic Acid
Cataplasm in the Treatment of Facial Chloasma
文章编号:
1008-6455（2019）01-0076-03
作者:
侯 勇; 刘 唯
Author(s):
HOU Yong;  LIU Wei
关键词:
[关键词]黄褐斑; 调Q激光; 氨甲环酸巴布剂; 联合治疗; 复发率
Keywords:
Key words: chloasma;  Q-switched laser;  tranexamic acid cataplasm;  combined treatment;  recurrence rate
分类号:
R758.4+2
文献标志码:
A
摘要:
[摘要]目的：探讨调Q激光联合氨甲环酸巴布剂治疗面部黄褐斑的临床疗效。方法：将120例女性黄褐斑患者随机均分为
观察组（调Q激光联合氨甲环酸巴布剂治疗）和对照组（单纯调Q激光治疗），比较两组治疗的有效率、黄褐斑积分下降指
数、黄褐斑面积及严重程度（MASI）评分，生活质量、不良反应以及复发率。结果：治疗后，观察组和对照组的有效率分
别为88.33%和73.33%（P ＜0.05）；两组黄褐斑积分及MASI评分均明显减少（P ＜0.05）；两组间疗效比较，有显著性差
异（P ＜0.05）；两组黄褐斑积分下降指数比较，有显著性差异（P＜0.05）；两组皮肤病生活质量指数（DLQI）及黄褐斑生
活质量评分量表（MELA-SQOL）评分均明显降低（P ＜0.05），且两组治疗后有显著性差异（P ＜0.05）。治疗期间，两组不
良反应发生情况无显著性差异（P ＞0.05）；随访1年，观察组和对照组复发率分别为13.33%和28.33%，经比较差异有统计学
意义（P ＜0.05）。结论：采用调Q激光联合氨甲环酸巴布剂治疗面部黄褐斑，可有效祛除色素斑，减少色素沉着，改善患者
生活质量，临床疗效和安全性均较好。

Abstract:
Abstract: Objective To study the clinical efficacy of Q-switched laser combined with tranexamic acid cataplasm in the
treatment of facial chloasma. Methods 120 cases of female patients with chloasma were randomly divided into observation
group (Q-switched laser combined with tranexamic acid cataplasm) and control group (Q-switched laser). The effective
rate of treatment, decreased index of chloasma integral, mass area and severity index (MASI) score, quality of life, adverse
reactions and recurrence rate were compared between the two groups. Results After treatment, the effective rates of treatment
in observation group and control group were 88.33% and 73.33% respectively (P ＜0.05). The chloasma integral and MASI
score in the two groups were significantly reduced (P ＜0.05), and there was a significant difference between the two groups
after treatment (P ＜0.05), and there was a statistically significant difference between the two groups in the decreased index of
chloasma integral (P ＜0.05). The scores of dermatology life quality index (DLQI) and MELA-subjective quality of life scale
(MELA-SQOL) were significantly decreased in the two groups (P ＜0.05), and the difference between the two groups after
treatment was statistically significant (P ＜0.05). There was no significant difference in the occurrence of adverse reactions
between the two groups during treatment (P ＞0.05). After 1 year of follow-up, there was statistically significant difference in the
recurrence rate between observation group and control group (13.33% vs 28.33%)] (P ＜0.05). Conclusion Q-switched laser
combined with tranexamic acid cataplasm for facial chloasma can effectively eliminate pigmentation spots, reduce pigmentation
and improve the quality of life, and it has positive clinical efficacy and safety.

相似文献/References:

[1]卫 艳,魏跃钢. 魏跃钢教授从补肾论治黄褐斑经验总结[J].中国美容医学,2018,(04):118.
　WEI Yan,WEI Yue-gang. Professor Wei Yuegang TreatChloasma by Tonifying the Kidney Experience Summary[J].Medical Aesthetics and Beauty,2018,(01):118.
[2]石莹莹,陈 炜,王露萍,等. 强脉冲光联合氨甲环酸治疗面部黄褐斑MASI评分观察[J].中国美容医学,2018,(05):36.
　SHI Ying-ying,CHEN Wei,WANG Lu-ping,et al. Observation on MASI Score of Intense Pulsed Light IPL Combined with Oral Transamin in the Treatment of Chloasma[J].Medical Aesthetics and Beauty,2018,(01):36.
[3]张 芳. 中药联合果酸治疗黄褐斑及RCM下影像变化[J].中国美容医学,2018,(08):130.
　ZHANG Fang.The Combination of Traditional Chinese Medicine and Glycolic Acid Peeling Treat Melasma and Its Imaging Changes in RCM[J].Medical Aesthetics and Beauty,2018,(01):130.
[4]贾 菲,吴风琴,张 倩,等.果酸治疗黄褐斑30例临床分析[J].中国美容医学,2018,(09):21.
　JIA Fei,WU Feng-qin,ZHANG Qian,et al.Clinical Efficacy of Alpha-hydroxy Acid for Treatment of 30 Cases of Melasma[J].Medical Aesthetics and Beauty,2018,(01):21.
[5]孙林潮,陶 卫,屈新华,等. 黄褐斑的整合治疗[J].中国美容医学,2018,(10):5.
　SUN Lin-chao,TAO Wei,QU Xin-hua,et al. Integrated Treatment of Melasma[J].Medical Aesthetics and Beauty,2018,(01):5.
[6]陆小萍,付继成. 维生素C结合光子嫩肤治疗老年黄褐斑效果研究[J].中国美容医学,2018,(10):42.
　LU Xiao-ping,FU Ji-cheng. Therapeutic Effect of Vitamin C Combined with Photorejuvenation on Aged Chloasma[J].Medical Aesthetics and Beauty,2018,(01):42.
[7]马慧敏,陈 军,冯仁洋.2013年至2017年1 766例就医者首次光电美容治疗情况分析[J].中国美容医学,2018,(11):43.
　MA Hui-min,CHEN Jun,FENG Ren-yang.Analysis the Aim of 1 766 Visitors of Cosmetic Department from 2013 to 2017[J].Medical Aesthetics and Beauty,2018,(01):43.
[8]张孟丽,张二佳,黄玉清,等. 皮秒翠绿宝石激光点阵模式治疗黄褐斑疗效观察[J].中国美容医学,2019,(05):4.
　ZHANG Meng-li,ZHANG Er-jia,HUANG Yu-qing,et al. Efficacy of the Fractional Picosecond Alexandrite Laser in the Treatment of Melasma[J].Medical Aesthetics and Beauty,2019,(01):4.
[9]刘 冰 齐 婧 综述,李承新 审校. 黄褐斑的光电治疗进展[J].中国美容医学,2019,(05):15.
　LIU Bing,QI Jing,LI Cheng-xin. Progress in Laser and Light Therapy of Melasma[J].Medical Aesthetics and Beauty,2019,(01):15.
[10]顾汉江 综述,曾维惠 审校. 黄褐斑发病机制中黑色素相关的信号分子及通路[J].中国美容医学,2019,(05):19.
　GU Han-jiang,ZENG Wei-hui. The Signal Molecules and Pathways Related to Melanin in the Pathogenesis of Melisma[J].Medical Aesthetics and Beauty,2019,(01):19.
[11]高 妮,李朝阳,王媛丽,等. 调Q红宝石点阵激光治疗难治性黄褐斑一例[J].中国美容医学,2019,(05):68.
　GAO Ni,LI Zhao-yang,WANG Yuan-li,et al. Case Report:Q-694nm pixel laser in the treatment of Refractory melasma[J].Medical Aesthetics and Beauty,2019,(01):68.

更新日期/Last Update: 2019-01-30