[1]李蕊联,曾维惠,刘晨越,等. Er:YAG 2 940nm激光与倍频KTP Nd:YAG激光联合免疫调节药物治疗顽固性扁平疣疗效分析[J].中国美容医学,2019,(09):1-3.
　LI Rui-lian,ZENG Wei-hui,LIU Chen-yue,et al. The Curative Effect of Er:YAG 2 940nm Laser and KTP Nd:YAG Laser Combined withImmunomodulating Drugs in the Treatment of Refractory Flat Warts[J].Medical Aesthetics and Beauty,2019,(09):1-3.
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 Er:YAG 2 940nm激光与倍频KTP Nd:YAG激光联合免疫调节药物治疗顽
固性扁平疣疗效分析
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《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2019年09期
页码:
1-3
栏目:
出版日期:
2019-09-05

文章信息/Info

Title:
 The Curative Effect of Er:YAG 2 940nm Laser and KTP Nd:YAG Laser Combined with
Immunomodulating Drugs in the Treatment of Refractory Flat Warts
文章编号:
1008-6455（2019）09-0001-04
作者:
李蕊联1; 曾维惠1; 刘晨越2; 李晓莉1; 王 梅1; 刘 艳1
Author(s):
LI Rui-lian1; ZENG Wei-hui1; LIU Chen-yue2; LI Xiao-li1; WANG Mei1; LIU Yan1
关键词:
 ; [关键词]扁平疣; 顽固性; Er:YAG 2 940nm激光; 倍频KTP Nd:YAG激光; 免疫调节药物; 疗效
Keywords:
Key words: flat warts;  refractory;  Er:YAG 2 940nm laser;  KTP Nd:YAG laser;  immunomodulating drugs;  curative effect
分类号:
R752.5+2
文献标志码:
A
摘要:

[摘要]目的：观察Er:YAG 2 940nm激光及倍频KTP Nd:YAG激光联合口服免疫调节药物治疗面颈部、手部顽固性扁平疣的疗
效和安全性。方法：收集2015年1月-2018年6月笔者科室门诊诊治的88例难治性多发性面颈部、手部扁平疣患者，根据皮损
颜色和皮损是否高出皮面分为三组。A组：皮损呈肤色,明显高出或未高出皮面，Er:YAG 2 940nm激光治疗；B组：皮损呈褐
色而未高出皮面，倍频KTP Nd:YAG激光治疗；C组：皮损呈褐色且高出皮面，倍频KTP Nd:YAG激光治疗1个月后给予Er:YAG
2 940nm激光治疗。激光治疗各组同时口服免疫调节药物（转移因子胶囊）4周。另收集30例非激光治疗的扁平疣患者为对照
组，口服转移因子胶囊，外用干扰素凝胶，疗程4周。各组治疗后均随访6个月。结果：激光联合口服免疫调节药物治疗后各
组有效率分别为87.88%、79.41%、85.71%，均显著高于对照组（20.00%，P ＜0.0001）。结论：根据扁平疣皮损的颜色和厚
度选择合理的治疗方案，可以取得较好的临床疗效，治疗周期短，不良反应少，复发率低。

Abstract:

Abstract: Objective To observe the efficacy and safety of laser therapy combined with immunomodulating drugs for refractory
multiple flat warts on the face、neck or hands for a better therapeutic regimen. Methods From January 2015 to June 2018,
88 patients with refractory multiple flat warts on the face、neck or hands were divided into three groups according to the
color and thickness of lesions. Group A: The lesions had no obvious pigmentation and significantly higher or not higher than
the skin,treated with Er 2 940nm laser in single spot mode; Group B: The lesions were brown but not raised above the skin
treated with KTP 532nm laser; Group C: The lesions were brown and raised above the skin，treated with KTP Nd:YAG laser and
Er:YAG 2 940nm laser in single spot mode. At the same time transfer factor capsules, one of the immunomodulatory drugs, were
taken in every laser treatment group. 30 cases of flat wart patients, treated with oral transfer factor capsules and topical interferon
gel, but without laser treatment were collected as control group. The course of treatment was 4 weeks. Results The effective rates
in the three laser treatment groups were 87.88%,79.41% and 85.71%, respectively. Which were significantly higher than that of
the control group (20.00%, P ＜0.0001). Conclusion It is effective and safe to treat flat warts with Er 2 940nm laser or/and KTP
Nd:YAG laser combined with immunomodulating drugs，resulting the satisfactory curative effects with short treatment period,
less adverse reactions and low recurrence rate.

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更新日期/Last Update: 2019-09-24