[1]奉水华,黄新灵,周忠志. rhEGF凝胶在肌皮瓣修复深度电击烧伤创面中的应用[J].中国美容医学,2020,(4):83-86.
　FENG Shui-hua,HUANG Xin-ling,ZHOU Zhong-zhi. Application Effect of rhEGF Gel in Perioperative Period of Myocutaneous Flap Repairfor Deep Electric Burn Wounds[J].Medical Aesthetics and Beauty,2020,(4):83-86.
点击复制

 rhEGF凝胶在肌皮瓣修复深度电击烧伤创面中的应用
()
分享到：

《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2020年4期
页码:
83-86
栏目:
出版日期:
2020-04-28

文章信息/Info

Title:
 Application Effect of rhEGF Gel in Perioperative Period of Myocutaneous Flap Repair
for Deep Electric Burn Wounds
文章编号:
1008-6455（2020）04-0083-04
作者:
 奉水华1; 黄新灵2; 周忠志2
Author(s):
 FENG Shui-hua1; HUANG Xin-ling2; ZHOU Zhong-zhi2
关键词:
 ; [关键词]电击烧伤; 重组人表皮生长因子凝胶; 肌皮瓣; 创面愈合; 瘢痕
Keywords:
 ; Key words: electric burn;  recombinant human epidermal growth factor gel;  musculocutaneous fl ap;  wound healing;  scar
分类号:
R647
文献标志码:
A
摘要:
[摘要]目的：探讨重组人表皮生长因子（rhEGF）凝胶在肌皮瓣修复深度电击烧伤创面中的应用效果。方法：选取2013年2
月-2018年10月笔者医院收治的84例深度电击烧伤患者，随机分为对照组与观察组，各42例。对照组采取常规清创及肌皮瓣
修复治疗，观察组另在清创后、植皮后给予rhEGF凝胶涂抹。对比清创后至肌皮瓣修复时间、二次清创率、修复术前创面感染
发生情况，并比较术后肌皮瓣成活及创面愈合情况，另对比供区创面愈合时间及住院时间，且术后随访12个月，观察供区创面
瘢痕形成情况。结果：观察组清创后至肌皮瓣修复时间明显短于对照组，二次清创率及修复术前创面感染发生率明显低于对照
组，差异有统计学意义（P＜0.05）。对照组与观察组术后肌皮瓣均完全成活（100.00%），其中创面一期愈合率分别为88.10%
（37/42）、92.86%（39/42），其余经换药及引流后均创面愈合，且供区均愈合良好。观察组供区创面愈合时间及住院时间明
显短于对照组，观察组术后6个月及12个月的供区创面瘢痕评分均明显低于对照组，差异有统计学意义（P ＜0.05）。结论：
在肌皮瓣修复深度电击烧伤创面中应用rhEGF凝胶，可明显缩短清创至肌皮瓣修复时间，减少二次清创及术前创面感染的发
生，术后创面愈合效果满意，并可加快供区创面愈合速度，缩短住院时间，可减少术后供区瘢痕形成。

Abstract:
Abstract: Objective To explore the application effect of recombinant human epidermal growth factor (rhEGF) gel in
perioperative period of myocutaneous fl ap repair for deep electric burn wounds. Methods 84 patients with deep electric burn
admitted to our hospital from February 2013 to October 2018 were selected, who were randomly divided into control group
and observation group, with 42 cases in each group. The control group was treated with routine debridement and myocutaneous
fl ap repair, while the observation group was given rhEGF gel smear in the perioperative period of myocutaneous fl ap repair.
The time from debridement to myocutaneous fl ap repair, the secondary debridement rate and the incidence of wound infection
before repair were compared, and the survival of myocutaneous fl aps and wound healing after operation were compared, and
the healing time of donor wounds and the hospitalization time were compared, then follow-up for 12 months after operation,
and the scar formations in the donor site wound were also observed. Results The time from debridement to myocutaneous fl ap
repair of the observation group was signifi cantly shorter than that of the control group, and the secondary debridement rate and
the incidence rate of wound infection before repair of the observation group were signifi cantly lower than those of the control
group, the difference were statistically signifi cant (P ＜0.05). The myocutaneous fl aps were complete survival (100.00%) in
the control group and the observation group after operation, and the fi rst-stage healing rate of the wounds of them was 88.10%
(37/42) and 92.86% (39/42) respectively, and the other wounds were healed after dressing change and drainage, and the all
donor site were healing well. The healing time of donor site wounds and the hospitalization time of the observation group were
signifi cantly shorter than those of the control group (P ＜0.05). The scar index of donor site wounds of the observation group at
6 months and 12 months after operation were signifi cantly lower than those of the control group (P ＜0.05). Conclusion The
application of rhEGF gel in the perioperative period of myocutaneous fl ap repair for deep electric burn wounds can signifi cantly
shorten the time from debridement to myocutaneous fl ap repair, reduce the incidence of secondary debridement and wound
infection before repair operation, of which the wound healing effect after operation is satisfactory, and it can accelerate the
wound healing speed of donor site, shorten the hospital stay and reduce the scar formation of donor site after operation.

相似文献/References:

[1]. 埋线美容专栏[J].中国美容医学,2018,(01):0.
　[J].Medical Aesthetics and Beauty,2018,(4):0.
[2]杨 震. 应用透明质酸颏部填充联合A型肉毒毒素咬肌注射重塑面部下1/3轮廓的效果观察[J].中国美容医学,2018,(03):1.
　YANG Zhen. Effect of Hyaluronic Acid Chin Filling Combined with Botulinum Toxin Type A Masseter Muscle Injection to Reconstruct the Facial Contour of the Lower 1/3[J].Medical Aesthetics and Beauty,2018,(4):1.
[3]祝闽辉,张栋梁,叶祥柏,等. 皮肤软组织扩张术埋置注液期并发症危险因素研究[J].中国美容医学,2018,(03):4.
　ZHU Min-hui,ZHANG Dong-liang,YE Xiang-bo,et al. Risk Factors of Complications after Tissue Expasion[J].Medical Aesthetics and Beauty,2018,(4):4.
[4]刘申松,杨永成. 自体脂肪颗粒移植联合假体隆乳术在哺乳后乳腺萎缩整形术中的应用[J].中国美容医学,2018,(03):9.
　LIU Shen-song,YANG Yong-cheng. Application of Autologous Fat Granule Graft Combined with Prosthesis Combined Augmentation Mammoplasty in Breast Reconstruction of Breast Atrophy Patients after Breast-feeding[J].Medical Aesthetics and Beauty,2018,(4):9.
[5]韩 星,胡守舵,陈晓芳,等.自体脂肪颗粒移植促进手部年轻化的临床观察[J].中国美容医学,2018,(03):12.
　HAN Xing,HU Shou-duo,CHEN Xiao-fang,et al. The Effect of Autologous Fat Grafting in Hand Rejuvenation[J].Medical Aesthetics and Beauty,2018,(4):12.
[6]李胜旭,苏映军,杨 宽,等. 封闭负压引流技术在先天性并指分指植皮术中的应用[J].中国美容医学,2018,(03):15.
　LI Sheng-xu,SU Ying-jun,YANG Kuan,et al. Application of Vacuum Sealing Drainage for Skin Graft in Patients with Congenital Syndactyly of the Hand[J].Medical Aesthetics and Beauty,2018,(4):15.
[7]陈 波,路 会,马 力,等. 钝针皮下层扇形注射透明质酸矫正面颊部凹陷[J].中国美容医学,2018,(03):18.
　CHEN Bo,LU Hui,MA Li,et al. Correction of Cheek Depression by Fanshaped Hyaluronic Acid Injection in Subcutaneous Layers with Blunt Needle[J].Medical Aesthetics and Beauty,2018,(4):18.
[8]曾德斌,栗鹏程,邱勋永,等. 不同超薄游离穿支皮瓣修复手部软组织缺损效果比较[J].中国美容医学,2018,(03):21.
　ZENG De-bin,LI Peng-cheng,QIU Xun-yong,et al. Comparison on the Repair Effect of Different Ultrathin Free Perforator Flaps in the Treatment of Patients with Soft Tissue Defect of Hand[J].Medical Aesthetics and Beauty,2018,(4):21.
[9]程 定,崔树英,郑 乐,等. 改道引流联合VSD技术修复会阴部撕裂伤的临床研究[J].中国美容医学,2018,(03):24.
　CHENG Ding,CUI Shu-ying,ZHENG Le,et al. Clinical Study on Diverted Drainage Combined with Vacuum Sealing Drainage Technique to Repair the Laceration of the Perineum[J].Medical Aesthetics and Beauty,2018,(4):24.
[10]李云峰,吴泽勇,黄海华,等. 全厚皮片游离移植矫治儿童足背瘢痕挛缩畸形[J].中国美容医学,2018,(03):27.
　LI Yun-feng,WU Ze-yong,HUANG Hai-hua,et al. Full-thickness Skin Graft for the Treatment of Cicatricial Contracture of the Dorsum of Foot in Children[J].Medical Aesthetics and Beauty,2018,(4):27.

更新日期/Last Update: 2020-04-28