[1] 魏 瑾,唐先发,杨振海,等. 我国北方四省市306例雀斑患者临床流行病学分析[J].中国美容医学,2020,(7):43-45.
　[J].Medical Aesthetics and Beauty,2020,(7):43-45.
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 我国北方四省市306例雀斑患者临床流行病学分析
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《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2020年7期
页码:
43-45
栏目:
出版日期:
2020-07-10

文章信息/Info

文章编号:
1008-6455（2020）07-0043-03
作者:
 魏 瑾1; 2 ; 唐先发3 ; 杨振海4 ; 李文海5 ; 贾振宇6
关键词:
 [关键词]雀斑; 临床分析; 流行病学; 表型; 临床特征
分类号:
R758.4+3
文献标志码:
A
摘要:
[摘要]目的：探讨我国四省市雀斑患者的临床流行病学特征。方法：回顾性分析2018年1月1日-2018年12月31日我国四省市
皮肤科门诊诊治的306例雀斑患者的社会人口学特征、表型、家族聚集性等特点。结果：306例雀斑患者中，平均首次发病年龄
（10.23±5.76）岁，72.22%(221/306)的患者有雀斑家族遗传史。先证者的家系中患有雀斑的男女比例为1:1.26。有家族史者
发病年龄早于无家族史者。不同地区间的首次发病年龄、表型无统计学差异，病情加重季节主要为夏季，日光暴露为雀斑加
重的主要诱因。结论：环境与遗传因素在雀斑的发生和发展中起重要作用，目前女性雀斑患者对治疗具有显著的迫切性。

Abstract:
Clinical Epidemiological Analysis of 306 Cases of Freckles in Four Cities of Northern China
WEI Jin1，2, TANG Xian-fa3, YANG Zhen-hai4, LI Wen-hai5, JIA Zhen-yu6
(1.Department of Dermatology and Venereology,Being Ditan Hospital Affi liated to Capital Medical University,Beijing
100015,China; 2.Department of Dermatology and Plastic Surgery,China Aerospace 731 Hospital, Beijing 100074, China; 3.
Department of Dermatology, the First Affi liated Hospital of Anhui Medical University, Hefei 230022, Anhui, China;
4. Department of Dermatology, the First Hospital of China Medical University,Shenyang 110001,Liaoning, China; 5.Department
of Dermatology,Peking University People’s Hospital,Beijing 100044,China; 6. Department of Dermatology,Heji Hospital
Affi liated to Changzhi Medical College,Changzhi 046011,Shanxi,China)
Abstract: Objective To analyze the clinical epidemiological characteristics of patients with freckles in four cities of China.
Methods A retrospective analysis was done by collecting the clinical and epidemilolgical data of 306 patients with freckles in
four cities of China from January 1st, 2018 to December 31st, 2018. EpiData 3.1 and SPSS 22.0 statistical softwares were used
for data analysis. Results Among the 306 patients, the total average age of fi rst onset was (10.23±5.76 )years old. And 72.22%
(221/306) of patients have a family genetic history. The gender ratio of relatives with freckles is 1:1.26. The age at onset was
younger in patients with family history than in those without. There was no statistical difference in the age of fi rst onset and
phenotype between different regions. The exacerbation of freckles was often occurred in summer, and sunlight exposure was
the main cause of the aggravation of freckles. Conclusion Environment and genotypes may play an important role in the
pathogenesis and development of freckles. Currently female freckle patients have a more signifi cant urgency for treatment.
Key words: freckles;clinical study;epidemiology;phenotype;clinical characteristics

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更新日期/Last Update: 2020-07-22