中西药联合5-氨基酮戊酸光动力疗法治疗囊肿型痤疮疗效观察<br />-《中国美容医学》

文章信息/Info

Title:: Observation of Effect of Chinese and Western Medicine Combined with
5-aminolevulinic Acid Photodynamic Therapy on Cystic Acne

文章编号:: 1008-6455（2020）12-0016-04

作者:: 刘玉东¹; 史玉玲² ; 李秀丽²

Author(s):: LIU Yu-dong1; SHI Yu-ling2; LI Xiu-li2

关键词:: [关键词]雷公藤多苷片; 泰尔丝胶囊; 5-氨基酮戊酸; 光动力疗法; 囊肿型痤疮; 炎症因子

Keywords:: Key words:tripterygium glycosides; isotretinoin capsules; 5-aminolevulinicacid; photodynamic therapy; cystic acne; inflammatory factors

分类号:: R758.73+3

文献标志码:: A

摘要:: [摘要]目的：评价中西药联合5-氨基酮戊酸光动力疗法治疗囊肿型痤疮患者的临床疗效。方法：选择2018年6月-2019年9月
笔者医院收治的73例囊肿型痤疮患者，随机分为试验组（38例）和对照组（35例）。两组均采用5-氨基酮戊酸光动力疗法作
为常规治疗，对照组给予泰尔丝胶囊治疗，试验组在对照组的基础上使用雷公藤多苷治疗，两组患者均治疗30d。治疗后观
察两组临床疗效、炎症因子水平、囊肿数量、皮损减少量及不良反应情况。结果：治疗后，试验组有效率明显高于对照组
（P ＜0.05）；两组患者IL-8、TNF-α水平均低于治疗前，比较差异具有统计学意义（P ＜0.05）；治疗后，两组囊肿数量均
低于治疗前，两组比较差异具有统计学意义（P ＜0.05），试验组皮损减少量显著高于对照组（P ＜0.05）；两组患者不良反
应发生率比较无显著性差异（P ＞0.05）。结论：中西药联合ALA-PDT治疗囊肿型痤疮可提高疗效，降低炎症反应，增加皮损
减少量。

Abstract:: Abstract:Objective To evaluate the clinical efficacy of Chinese and Western medicine combined with 5-aminolevulinic acid
photodynamic therapy(ALA-PDT) in the treatment of cystic acne patients. Methods From June 2018 to September 2019, 73
patients with cystic acne treated in hospital were randomly divided into experimental group (38 cases) and control group (35
cases). Both groups were treated with ALA-PDT as routine therapy. The control group was treated with isotretinoin capsules.
The experimental group was treated with tripterygium glycosides on the basis of the control group. Both groups were treated
for 30 days. Observe the clinical efficacy, levels of inflammatory factors, number of cysts, reduction of skin lesions and adverse
reactions in both groups. Results After treatment, the effective rate of the test group was significantly higher than that of the
control group (P ＜0.05). The levels of IL-8 and TNF-α in the two groups of patients were lower than before treatment, and the
difference between the two groups was statistically significant (P ＜0.05). The number of cysts in the two groups was lower than
before treatment,the difference between the two groups was statistically significant (P ＜0.05), the amount of skin lesions in the
test group was significantly higher than that in the control group (P ＜0.05).There was no significant difference in the reaction
rate (P ＞0.05). Conclusion Chinese and Western medicine combined with ALA-PDT in the treatment of cystic acne patients
can improve its efficacy, reduce inflammation and increase the amount of skin lesions.

《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

文章信息/Info

常用功能

导航/Navigate

工具/Tools

统计/Statistics