注射用聚左旋乳酸在体表软组织充填中的应用现状-《中国美容医学》

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作者:: 董诚挚¹ 综述; 朱辉² 审校; (1.浙江省立同德医院整形外科浙江杭州 310020 ;2.深圳平安龙华医院整形外科广东深圳 518000 )

Keywords:: Poly-L-lactin acid; injectant; filler; soft tissue loss; clinical application

摘要:: 聚左旋乳酸（Poly-L-lactin acid,PLLA）在医学领域已有充分应用。2004年,美国FDA批准塑然雅注射用聚左旋乳酸作为一种填充材料治疗与艾滋病相关的面部萎缩。此后,多个注射用聚左旋乳酸品牌相继在不同国家或地区获批上市。近年来，注射用聚左旋乳酸被用来改善多部位软组织凹陷或缺失引起的外观不满意。本文从注射用聚左旋乳酸理化性质、基本原理、制备工艺、使用方法、临床疗效、安全性等方面对聚左旋乳酸在整形外科中的应用现状综述如下。

Abstract:: Poly-L-lactin acid(PLLA) has been used in clinic for a long time. Sculpture was allowed in curing AIDS-assist facial atrophy by FDA in 2004. Lately, more PLLA products were allowed in other countries. PLLA for injection is used as a filler to improve the unsatisfaction of lipoatrophy or fat volume loss. Here,the physiochemical characteristics,the preparation process, the usage method,the Clinical Efficacy,the safety of the PLLA in plastic surgery, are reviewed.