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《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:

期数:

2023年10期

页码:

201-205

栏目:

出版日期:

2023-10-10

文章信息/Info

Title:

The Fundamental and Clinical Research Progress on Polycaprolactone (PCL) -Based Collagen-Stimulator

文章编号:

1008-6455（2023）10-0201-04

作者:

黄乃艳¹ 贾 康² 综述; 刘红梅¹ 审校

?北京梅颜医疗美容诊所1.美容皮肤科;2.美容外科 北京 100027 )

Author(s):

arial;  helvetica;  sans-serif;">HUANG Naiyan¹ ; JIA Kang² ; LIU Hongmei¹

(1.Department of Cosmetic Dermatology; 2.Department of Cosmetic Surgery,MEIYAN Aesthetic Plastic Medical Clinic,Beijing 100027,China)

关键词:

聚己内酯微球; 填充剂; 胶原刺激剂; 适应证; 安全性?/html>

Keywords:

polycaprolactone;  fi ller;  collagen stimulator;  indication;  safety

分类号:

R622

DOI:

10.15909/j.cnki.cn61-1347/r.005951

文献标志码:

A

摘要:

近年来，随着注射微整形需求量的增加，填充剂的类型也不断出现。一种基于聚己内酯微球（Polycaprolactone,PCL） 的填充剂伊妍仕（Ellansé?）刚刚获批进入中国市场，是新一代的胶原刺激剂，具有即刻填充、刺激自身胶原新生的作 用。本文综述了基于PCL的填充剂的结构、生物降解途径和生物安全性，并对其基础研究和临床应用进行了详细的描述，以 期为临床医生的使用提供参考。?/html>

Abstract:

In recent years, as the demand for injection microplastic surgery has increased, types of fi llers have also continued to appear. Ellansé, a fi ller based on polycaprolactone (PCL) microspheres, has just been approved to enter the Chinese market. It is a new generation of collagen stimulant that can instantly fi ll and stimulate its own collagen regeneration. This article reviews the structure, biodegradation pathways and biosafety of PCL-based fillers, and provides a detailed description of its basic research and clinical applications in order to provide references for clinicians’ use.

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更新日期/Last Update: 2023-11-13