[1]林士伟,魏茗蕾,孔 静,等.308 nm准分子光联合毫火针治疗眼睑处白癜风自身对照临床研究[J].中国美容医学,2022,(3):37-40.
　LIN Shiwei,WEI Minglei,KONG Jing,et al.A Self-controlled Clinical Study of 308 nm Excimer Laser Combined with Filiform Fire Needle in the Treatment of Eyelid Vitiligo[J].Medical Aesthetics and Beauty,2022,(3):37-40.
点击复制

308 nm准分子光联合毫火针治疗眼睑处白癜风自身对照临床研究()
分享到：

《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2022年3期
页码:
37-40
栏目:
出版日期:
2022-03-10

文章信息/Info

Title:
A Self-controlled Clinical Study of 308 nm Excimer Laser Combined with Filiform Fire Needle in the Treatment of Eyelid Vitiligo
文章编号:
1008-6455（2022）03-0037-03
作者:
林士伟1; 魏茗蕾1; 孔 静1; 尹 智2
(1.南京市高淳人民医院皮肤科 江苏 南京 211300 ;2.南京医科大学第一附属医院皮肤科 江苏 南京 210029)
Author(s):
LIN Shiwei1; WEI Minglei1; KONG Jing1; YIN Zhi2
(1.Department of Dermatology, Nanjing Gaochun People’s Hospital, Nanjing 211300, Jiangsu,China; 2. Department of Dermatology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029,Jiangsu, China)
关键词:
308 nm准分子光; 毫火针; 眼睑; 白癜风; 自身对照
Keywords:
308 nm excimer laser;  filiform fire needle;  eyelid;  vitiligo;  self-control
分类号:
R758.4+1
文献标志码:
A [
摘要:
目的：分析308nm准分子光联合毫火针治疗眼睑处白癜风的临床疗效。方法：前瞻性入选2018年9月-2020年8月笔者医院就诊的62例眼睑处白癜风患者为研究对象，遵循自身对照原则，对照组采取308nm准分子光照射治疗，观察组在对照组基础上加用毫火针治疗。比较两组皮损治疗前后的白斑面积，比较治疗后两组间的复色率、临床疗效以及总满意度。结果：治疗前，两组皮损白斑面积比较无明显差异；治疗后4、8、12周，观察组白斑面积均显著小于对照组，观察组复色率均大于对照组；治疗结束后，观察组皮损显效率高于对照组（58.06%vs.35.48%），有效率也高于对照组（91.94% vs.77.42%），观察组总满意度（91.93%）高于对照组（79.03%），以上差异均有统计学意义（P＜0.05）。结论：308nm准分子光联合毫火针治疗眼睑处白癜风临床疗效更加显著，且未明显增加不良反应，值得临床推广应用。
Abstract:
Objective To analyze the effect of 308 nm excimer laser combined with filiform fire needle in the treatment of vitiligo at the eyelid. Methods A total of 62 patients with vitiligo on eyelids who visited our hospital from September 2018 to August 2020 were prospectively enrolled. This study followed the principle of self-control, the control group was treated with 308 nm excimer laser irradiation. On the basis of the control group, the observation group was treated with filiform fire needle. The leukoplakia area before and after treatment was compared between the two groups, and the repigmentation rate, clinical efficacy, and satisfaction rate were compared between the two groups after treatment. Results At 4, 8 and 12 weeks after treatment, the area of leukoplakia in the observation group was significantly smaller than that in the control group, and the repigmentation in the observation group was greater than that in the control group. After the end of treatment, the markedly effective rate in the observation group was higher than that in the control group (58.06% vs. 35.48%), and the effective rate was also higher than that in the control group (91.94% vs.77.42%). The satisfaction rate of observation (91.93%) was higher than that of control group (79.03%). The above differences were statistically significant (P ＜0.05). Conclusion 308 nm excimer laser combined with filiform fire needle has more significant clinical efficacy in the treatment of eyelid vitiligo, without significantly increasing adverse reactions, and it is worthy of clinical application.

相似文献/References:

[1] 晏 卉,李 倩,周 蓓,等. 毫火针联合中药药膜外敷治疗轻中度痤疮疗效观察[J].中国美容医学,2020,(5):117.
　 YAN Hui,LI Qian,ZHOU Bei,et al. Effi cacy Observation on Filiform Fire Needle Combined with Chinese MedicinePowder Mask on Mild and Moderate Acne[J].Medical Aesthetics and Beauty,2020,(3):117.
[2] 宗淑芳,刘 霞,丁小杰,等. 毫火针联合羟氯喹治疗玫瑰痤疮临床观察[J].中国美容医学,2020,(10):157.
　 ZONG Shu-fang,LIU Xia,DING Xiao-jie,et al. Clinical Observation on the Treatment of Rosacea with Milli-fire Needle andHydroxychloroquine[J].Medical Aesthetics and Beauty,2020,(3):157.
[3] 任 虎. 毫火针辅助308nm准分子光联合他克莫司软膏对白癜风患者疗效及免疫功能的影响[J].中国美容医学,2021,(3):102.
　 REN Hu. Effect of Millifire Needle Assisted 308nm Excimer Laser Combine with TacrolimusOintment on Immune Function of Patients with Vitiligo[J].Medical Aesthetics and Beauty,2021,(3):102.
[4]丁小杰,蒋 培,宗淑芳,等.毫火针联合得宝松及复方甘草酸苷胶囊对斑秃患者免疫功能的影响[J].中国美容医学,2021,(12):116.
　DING Xiao-jie,JIANG Pei,ZONG Shu-fang,et al.Efficacy of Milifire Needle Combined with Diprospan and Compound Glycyrrhizin Capsules on Alopecia Areata and its Influence on Immune Function[J].Medical Aesthetics and Beauty,2021,(3):116.
[5]徐婉妮,刘 靖,杨广智.复方甘草酸苷片联合他克莫司软膏及308 nm准分子光治疗白癜风皮损的修复效果观察[J].中国美容医学,2023,(4):84.
　XU Wanni,LIU Jing,YANG Guangzhi.Repair Effect of Compound Glycyrrhizin Tablet Combined with Tacrolimus Ointment and 308 nm Excimer Light on Skin Lesions in Vitiligo[J].Medical Aesthetics and Beauty,2023,(3):84.
[6]薛文杰,李 烁,王郁冲.毫火针联合多磺酸粘多糖乳膏治疗中重度痤疮临床疗效观察[J].中国美容医学,2023,(8):159.[doi:10.15909/j.cnki.cn61-1347/r.005857]
　XUE Wenjie,LI Shuo,WANG Yuchong.Clinical Observation of Filiform Fire Needle Combined with Polysulfonic Acid Mucopolysaccharide Cream in the Treatment of Moderate to Severe Acne[J].Medical Aesthetics and Beauty,2023,(3):159.[doi:10.15909/j.cnki.cn61-1347/r.005857]
[7]黄 丹,段德鉴,李 楚,等.长脉冲1 064 nm激光联合毫火针治疗囊肿型痤疮疗效观察[J].中国美容医学,2023,(10):74.[doi:10.15909/j.cnki.cn61-1347/r.005938]
　HUANG Dan,DUAN Dejian,LI Chu,et al.Clinical Effi cacy of Long Pulse 1 064 nm Laser Combined with Milli-fi re Needle in the Treatment of Cystic Acne[J].Medical Aesthetics and Beauty,2023,(3):74.[doi:10.15909/j.cnki.cn61-1347/r.005938]
[8]孙圆圆,赵世享,陈 秋,等.308 nm准分子光联合复方倍他米松治疗进展期白癜风疗效及对复发的影响[J].中国美容医学,2024,(8):119.
　SUN Yuanyuan,ZHAO Shixiang,Chen Qiu,et al.Effi cacy of 308 nm Excimer Laser Combined with Compound Betamethasone in the Treatment of Patients with Advanced Vitiligo and Its Infl uence on Recurrence[J].Medical Aesthetics and Beauty,2024,(3):119.
[9]王 莉,杨 浩,陈 梅,等.点阵CO2激光联合308 nm准分子光治疗面部白癜风的临床效果研究[J].中国美容医学,2024,(10):57.
　WANG Li,YANG Hao,CHEN Mei,et al.Effect of Fractional CO2 Laser Combined with 308 nm Excimer Laser in Treating Facial Vitiligo[J].Medical Aesthetics and Beauty,2024,(3):57.

更新日期/Last Update: 2022-04-06