[1]包树明 综述,诺布央卓 左 蕊 向小燕 审校.microRNA与皮肤衰老的研究进展[J].中国美容医学,2024,(4):186-190.
　BAO Shuming,NUOBU Yangzhuo,ZUO Rui,et al.Research Progress of microRNA and Skin Aging[J].Medical Aesthetics and Beauty,2024,(4):186-190.
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microRNA与皮肤衰老的研究进展()
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《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2024年4期
页码:
186-190
栏目:
出版日期:
2024-04-10

文章信息/Info

Title:
Research Progress of microRNA and Skin Aging
文章编号:
1008-6455（2024）04-0186-05
作者:
包树明1; 2 综述; 诺布央卓1; 2 左 蕊1; 2 向小燕1; 2 审校
(1.川北医学院附属医院整形美容烧伤外科 四川 南充 637000 ;2.川北医学院 四川 南充 637000 )
Author(s):
arial;  helvetica;  sans-serif;">BAO Shuming1 ;  arial;  helvetica;  sans-serif;">2;  NUOBU Yangzhuo1; 2;  ZUO Rui1; 2;  XIANG Xiaoyan1; 2
(1.Department of Plastic, Cosmetic and Burn Surgery, Affi liated Hospital of North Sichuan Medical College, Nanchong 637000, Sichuan, China; 2.North Sichuan Medical College, Nanchong 637000, Sichuan, China)
关键词:
微小RNA; 衰老; 角质形成细胞; 成纤维细胞; 黑素细胞; 免疫细胞
Keywords:
miRNA;  senescence;  keratinocytes;  fi broblasts;  melanocytes;  immune cells
分类号:
R339.3+ 8
文献标志码:
A
摘要:
皮肤衰老是人体衰老最直观的表现，目前已发现皮肤衰老过程中伴着microRNA（miRNA）表达的改变。这表明miRNA可 能参与了皮肤衰老过程的调控，可能有用于作为皮肤衰老的标志物和抗衰老治疗策略。本文旨在探讨miRNA如何通过影响皮肤 角质形成细胞、成纤维细胞、免疫细胞及黑素细胞的增殖、分化、细胞稳定、蛋白通路、细胞周期等方面导致皮肤的衰老。
Abstract:
Skin aging is the most intuitive manifestation of human aging. Currently, it has been found that the skin aging process is accompanied by the change of microRNA (miRNA) expression. This suggests that miRNA may be involved in the regulation of skin aging. This article aims to explore how miRNA can cause skin aging by aff ecting the aging of keratinocytes, fi broblasts, immune cells and melanocytes.

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更新日期/Last Update: 2024-04-19