[1]李倩云,徐建荣,张 凡.微针射频联合rb-bFGF凝胶治疗早期面部痤疮瘢痕疗效分析[J].中国美容医学,2024,(8):112-115.
　LI Qianyun,XU Jianrong,ZHANG Fan.Curative Effect Analysis of Microneedle Radiofrequency Combined with rb-bFGF Gel in Patients with Early Facial Acne Scars[J].Medical Aesthetics and Beauty,2024,(8):112-115.
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微针射频联合rb-bFGF凝胶治疗早期面部痤疮瘢痕疗效分析()
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《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2024年8期
页码:
112-115
栏目:
出版日期:
2024-08-10

文章信息/Info

Title:
Curative Effect Analysis of Microneedle Radiofrequency Combined with rb-bFGF Gel in Patients with Early Facial Acne Scars
文章编号:
1008-6455（2024）08-0112-03 Curative Effe
作者:
李倩云; 徐建荣; 张 凡
(马鞍山市妇幼保健院皮肤性病科 安徽 马鞍山 243000 )
Author(s):
LI Qianyun;  XU Jianrong;  ZHANG Fan
( Department of Dermatology and Venereology, Ma’anshan Maternal and Child Health Hospital, Ma’anshan 243000, Anhui, China )
关键词:
微针射频; 重组牛碱性成纤维细胞生长因子凝胶; 面部痤疮瘢痕; 疗效
Keywords:
microneedle radiofrequency;  recombinant bovine basic fi broblast growth factor gel;  facial acne scar;  curative eff ect
分类号:
R619.6
文献标志码:
A
摘要:
目的：探讨分析微针射频（Microneedle radiofrequency，MRF）联合重组牛碱性成纤维细胞生长因子（Recombinant bovine basic fibroblast growth factor，rb-bFGF）凝胶治疗早期面部痤疮瘢痕患者的疗效。方法：选取2022年1月-2023 年6月马鞍山市妇幼保健院收治的面部痤疮瘢痕患者62例，据简单随机法分为单一组（n=31，MRF治疗）和联合组（n=31， MRF 联合rb-bFGF凝胶治疗），2个月1次，共治疗6个月。比较两组临床疗效、水肿时间、红斑消退时间及结痂时间；于治疗 前后对比瘢痕基底深度、痤疮瘢痕权重（Echelle d’evaluation clinique des cicatrices d’acne，ECCA）评分、温哥华 瘢痕量表（Vancouver scar scale，VSS）；并记录不良反应。结果：联合组总有效率较单一组更高（P＜0.05）。联合组 水肿时间、红斑消退时间及结痂时间均短于单一组（P＜0.05）。与治疗前比较，治疗2个月、6个月后两组瘢痕基底深度、 ECCA 及VSS评分均降低，且联合组上述指标较单一组更低（P＜0.05）。联合组不良反应低于单一组（P＜0.05）。结论：微 针射频联合rb-bFGF凝胶治疗面部痤疮瘢痕患者疗效显著，不仅可改善瘢痕症状，还可促使瘢痕快速恢复，减少不良反应。
Abstract:
Objective To explore the curative eff ect of microneedle radiofrequency (MRF) combined with recombinant bovine basic fi broblast growth factor ( rb-bFGF) gel in patients with early facial acne scars. Methods A total of 62 patients with facial acne scars at Ma’anshan Maternal and Child Health Hospital were enrolled between January 2022 and June 2023. According to the simple randomization method, they were divided into the single group (n=31, MRF) and the combination group (n=31, MRF combined with rb-bFGF gel). All patients were treated for 6 months (once every 2 months). The clinical curative eff ect, edema time, recession time of erythema and escharosis time, depth of scar base, scores of Echelle d’evaluation clinique des cicatrices d’acne (ECCA), and Vancouver Scar Scale (VSS) were compared between the two groups before and after treatment. The adverse reactions were recorded. Results The total response rate of the combination group was higher than that of the single group (P ＜0.05). The edema time, recession time of erythema, and escharosis time in the combination group were shorter than those in the single group (P ＜0.05). After 2 and 6 months of treatment, the depth of the scar base, ECCA, and VSS scores were decreased in both groups, which were lower in the combination group than in the single group (P＜0.05). The incidence of adverse reactions in the combination group was lower than that in the single group (P＜0.05). Conclusion The curative eff ect of MRF combined with rb-bFGF gel is signifi cant in patients with facial acne scars, which can not only improve scar symptoms but also promote rapid scar recovery and reduce adverse reactions.

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更新日期/Last Update: 2024-08-17