[1]唐 莉,王 宇,李 满. 瑞芬太尼与氯胺酮复合异丙酚静脉麻醉用于重睑术中的疗效对比[J].中国美容医学,2018,(05):9-12.
 TANG Li,WANG Yu,LI Man. Effect of Remifentanil and Ketamine Combined with Propofol Intravenous Anesthesiaon Double Eyelid Surgery[J].Medical Aesthetics and Beauty,2018,(05):9-12.
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 瑞芬太尼与氯胺酮复合异丙酚静脉麻醉用于重睑术中的疗效对比
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《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2018年05期
页码:
9-12
栏目:
出版日期:
2018-06-10

文章信息/Info

Title:
 Effect of Remifentanil and Ketamine Combined with Propofol Intravenous Anesthesiaon Double Eyelid Surgery
文章编号:
1008-6455(2018)05-0009-04
作者:
 唐 莉1王 宇1李 满2
Author(s):
 TANG Li1WANG Yu1LI Man2
关键词:
 [关键词]重睑术麻醉效果安全性瑞芬太尼氯胺酮
Keywords:
 Key words: double eyelid surgery anesthesia safety remifentanil ketamine
分类号:
R622
文献标志码:
A
摘要:

[摘要]目的:对比分析瑞芬太尼复合异丙酚和氯胺酮复合异丙酚静脉麻醉在重睑术中的麻醉效果及安全性,为重睑术麻醉方
案的选择提供参考。方法:纳入笔者医院2014年1月-2017年12月符合条件的重睑术就医者108例作为研究对象,按照手术顺
序编号,采用数字随机表法分为2组,每组54例。瑞芬太尼组采用瑞芬太尼复合异丙酚静脉麻醉,氯胺酮组采用氯胺酮复合
异丙酚麻醉,记录两组就医者围手术期氧合状态、通气状况及脑功能指标变化[平均动脉压(MAP)、心率(HR)、呼吸频
率(BR)、血氧饱和度(SpO2)、呼气末二氧化碳分压(PETC02)],及围手术期并发症发生情况等。结果:两组患者入室后
即刻、局麻后20min MAP、HR、BR、SpO2、PETC02比较差异无统计学意义(P >0.05),但瑞芬太尼组静脉麻醉即刻、局麻即
刻、局麻后10min MAP、HR、BR均明显低于氯胺酮组,差异有统计学意义(P <0.05)。瑞芬太尼组Ramsay 镇静评分(2~4
分)率为88.89%明显高于氯胺酮组的70.37%,差异有统计学意义(P <0.05)。瑞芬太尼组BCS舒适评分为(2.81±0.93)分
明显高于氯胺酮组的(2.41±0.72)分,差异有统计学意义(P <0.05)。瑞芬太尼组围手术期并发症发生率为11.11%明显
低于氯胺酮组的22.22%,差异有统计学意义(P <0.05)。结论:瑞芬太尼复合异丙酚用于重睑术麻醉综合效果优于氯胺酮
复合异丙酚麻醉方案,为手术创造了更优的麻醉效果,具有较高的临床价值。

Abstract:

Abstract: Objective To compare and analyze the effect and safety of remifentanil and ketamine combined with propofol
intravenous anesthesia, and to provide reference for the selection of the anesthesia scheme for the double eyelid operation.
Methods 108 cases of double eyelid surgery were included in our hospital from January 2014 to December 2017. According
to the number of the operation sequence, the digital random table was used to divide into two groups, with 54 cases in each
group. The remifentanil group was treated with remifentanil combined with propofol intravenous anesthesia. The ketamine
group was treated with ketamine combined with propofol. The changes of oxygen status, ventilation and brain function [mean
arterial pressure (MAP), heart rate (HR), respiratory frequency (BR)] were collected in two groups of patients. The blood
oxygen saturation (SpO2), the end expiratory carbon dioxide partial pressure (PETCO2), and the perioperative complications
were evaluated and compared. Results There were no significant differences in MAP, HR, BR, SpO2 and PETCO2 between the
two groups immediately after admission and 20min after local anesthesia(P >0.05). The MAP, HR and BR of the remifentanil
group were significantly lower than those of the ketamine group immediately after intravenous anesthesia, immediately after
local anesthesia and 10min after local anesthesia(P <0.05). The Ramsay sedation score (2-4 points) in the remifentanil group
was 88.89%, significantly higher than that in the ketamine group (70.37%, P <0.05). The BCS comfort score of the remifentanil
group was (2.81±0.93), which was significantly higher than that of the ketamine group (2.41±0.72, P <0.05). The incidence of
perioperative complications in remifentanil group was 11.11%, which was significantly lower than that in the ketamine group
(22.22%,P <0.05). Conclusion The combined effect of remifentanil and propofol in double eyelid anesthesia is better than that
of ketamine combined with propofol. It can create better anesthetic effect for the operation, and it has high clinical value.

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更新日期/Last Update: 2018-07-10