[1]叶文正,李词娟,吴一文,等. Mohs手术联合光动力治疗乳房外Paget病的临床观察[J].中国美容医学,2018,(06):4-6.
　YE Wen-zheng,LI Ci-juan,WU Yi-wen,et al. Clinical Observation of Mohs Surgery Combined with Photodynamic Therapy in the Treatment of Extramammary Paget’s Disease[J].Medical Aesthetics and Beauty,2018,(06):4-6.
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 Mohs手术联合光动力治疗乳房外Paget病的临床观察

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《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2018年06期
页码:
4-6
栏目:
出版日期:
2018-07-10

文章信息/Info

Title:
 Clinical Observation of Mohs Surgery Combined with Photodynamic Therapy in the Treatment of Extramammary Paget’s Disease
文章编号:
08-6455（2018）06-0004-03
作者:
 叶文正; 李词娟; 吴一文; 王珊珊; 王 兰; 方木平
Author(s):
YE Wen-zheng; LI Ci-juan; WU Yi-wen; WANG Shan-shan; WANG Lan; FANG Mu-ping
关键词:
 ; [关键词]Mohs手术; 光动力; 乳房外Paget病; 临床疗效; Wood灯
Keywords:
 ; Key words: Mohs surgery;  photodynamic therapy;  extramammary Paget’s disease;  clinical curative effect;  Wood’s lamp
分类号:
R622
文献标志码:
A
摘要:
[摘要]目的：观察Mohs手术联合光动力治疗乳房外Paget病的临床疗效。方法：8例确诊为乳房外Paget病患者纳入治疗观察，术前皮疹部位用ALA封包，Wood灯下标记手术边界，运用Mohs手术切除病灶，伤口拆线后每隔10d光动力治疗1次，总计治疗4次，随访半年观察其疗效。结果：纳入治疗的患者伤口均甲级愈合，未出现感染等并发症，随访半年无复发，外阴部形态结构功能无明显影响，患者就医满意度高。结论：Mohs手术联合光动力治疗外阴部位乳房外Paget病效果较好，病灶切除干净，患者术后恢复快，肿瘤复发率低，可作为外阴部乳房外Paget病的首选治疗方案。

Abstract:
Abstract: Objective To assess the effect of Mohs surgery combined with photodynamic therapy in the treatment of extramammary Paget’s disease. Methods A total of 8 cases of diagnosed with extramammary Paget’s disease were under observation. ALA solution was applied to the affected area before the operation, Wood’s lamp was used to determine the margin of the lesion. Mohs surgery was used to excise the lesions. The photodynamic therapy was performed once every 10 days after stitch removal, a total of 4 treatments were performed and followed up for six months. Results There were no complications postoperatively, such as surgical site infection, deformation of the vulva and delayed healing of incision, all the patients were advised regular follow-up and no recurrence of the tumor until the last follow-up done six months after the surgery, all the patients were satisfied with the effect of the treatment. Conclusion Mohs surgery combined with photodynamic therapy is effective for treating of extramammary Paget’s disease in the vulva region. The lesions are removed cleanly and the patients recover quickly after operation with low rate of tumor recurrence. This can be used as the first choice for treatment of extramammary Paget’s disease in the vulva.

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更新日期/Last Update: 2018-08-07