夫西地酸乳膏联合当归苦参丸治疗轻中度痤疮临床观察<br />-《中国美容医学》

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Title:: Fusidic Acid Cream Combined with Danggui Kushen Pill in the Treatment of Mild to Moderate Acne

文章编号:: 1008-6455(2018)06-0128-03

作者:: 徐文博¹; 沈立飞¹; 赵宇²

Author(s):: XU Wen-bo1; SHEN Li-fei1; ZHAO Yu2

关键词:: [关键词]夫西地酸乳膏; 当归苦参丸; 皮脂分泌; 血红素; 轻中度痤疮

Keywords:: Key words: fusidic acid cream; danggui kushen pill; sebum secretion; heme; mild to moderate acne

分类号:: R758.73+3

文献标志码:: A

摘要:: [摘要]目的：观察夫西地酸乳膏联合当归苦参丸治疗轻中度痤疮的临床疗效。方法：将2014年1月-2017年9月笔者科室收治
的轻中度痤疮患者按随机数字表法分为观察组与对照组，每组52例。对照组给予夫西地酸乳膏治疗，观察组夫西地酸乳膏联
合当归苦参丸治疗，对比两组患者临床疗效及炎性皮损、非炎性皮损的改善情况，并比较治疗前后面部皮脂含量、皮肤血红
素含量，统计不良反应发生率。结果：治疗后，观察组总有效率（78.85%）显著高于对照组（57.69%），差异有统计学意义
（P ＜0.05）；炎性皮损数、非炎性皮损数及总皮损数均显著下降并低于对照组；前额、鼻、脸颊等部位皮脂含量及皮肤血红素
含量均显著下降且低于对照组，差异具有统计学意义（P＜0.05）；两组不良反应发生率比较差异无统计学意义（P＞0.05）。结
论：夫西地酸乳膏联合当归苦参丸治疗轻中度痤疮不仅疗效佳，还可有效抑制皮脂分泌，降低皮肤血红素含量，且安全性高。

Abstract:: Abstract: Objective To observe the clinical curative effect of Fusidic Acid Cream combined with Danggui Kushen pill in the
treatment of mild to moderate acne. Methods Patients with mild to moderate acne who were admitted to the hospital from
January 2014 to September 2017 were divided into the observation group and the control group by the random number table
method, with 52 cases in each group. The control group was treated with Fusidic Acid Cream while the observation group was
treated with Fusidic Acid Cream combined with Danggui Kushen pill. The clinical curative effect, the relief of inflammatory
skin lesions and non-inflammatory skin lesions were compared between the two groups. The facial sebum content and the heme
content were compared before and after treatment, and the incidence of adverse reactions was statistically analyzed. Results
The total effective rate in the observation group (78.85%) was significantly higher than that in the control group (57.69%) after
treatment. The number of inflammatory skin lesions, non-inflammatory skin lesions, the total number of skin lesions sebum
levels in forehead, nose and cheeks and the hemoglobin level in the observation group decreased significantly after treatment
and were smaller than those in the control group (P ＜0.05). There was no significant difference between the two groups in
the incidence of adverse reactions (P ＞0.05). Conclusion Fusidic Acid Cream combined with Danggui Kushen pillis not
only effective in treating mild to moderate acne, but also can effectively inhibit sebum secretion and reduce the content of
hemoglobin in skin, with safety.

《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

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