[1]马佳慧,钟 心,秦泽雨,等. 中药面膜对痤疮动物模型治疗作用的实验研究[J].中国美容医学,2018,(07):72-74.
　MA Jia-hui,ZHONG Xin,QIN Ze-yu,et al. The Study of the Therapeutic Effect of Traditional Chinese Medicine Mask on the Acne Animal Models[J].Medical Aesthetics and Beauty,2018,(07):72-74.
点击复制

 中药面膜对痤疮动物模型治疗作用的实验研究
()
分享到：

《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2018年07期
页码:
72-74
栏目:
出版日期:
2018-08-10

文章信息/Info

Title:
 The Study of the Therapeutic Effect of Traditional Chinese Medicine Mask on the Acne Animal Models
文章编号:
1008-6455（2018）07-0072-04
作者:
 马佳慧1; 钟 心1; 秦泽雨1; 蔺红静1; 徐红丹2
Author(s):
 MA Jia-hui1; ZHONG Xin1; QIN Ze-yu1; LIN Hong-jing1; XU Hong-dan2
关键词:
 ; [关键词]中药面膜; 痤疮; 炎性因子; 治疗作用; 维A酸乳膏
Keywords:
Key words: Chinese medicine facial mask;  acne;  inflammatory factors;  therapeutic effect;  Vitamin A acid cream
分类号:
R285.5
文献标志码:
A
摘要:
[摘要]目的：探究中药面膜对痤疮动物模型的治疗作用。方法：将32只大鼠分为2组，即正常组（n =8）和造模组（n =24）。
采用痤疮丙酸杆菌方法造模，造模成功后分为模型组、维A酸组、药膜组，每组8只。模型组不做任何处理，维A酸组涂0.1%
维A酸乳膏，药膜组涂抹中药面膜，连续治疗2周后，用酶联免疫吸附法（Elisa）法检测各组大鼠血清IL-1α、IL-6、
TNF-α和IL-2的含量，采用免疫印迹（Western Blot）的方法测定各组大鼠痤疮组织中IL-1α、IL-6、TNF-α和IL-2的表
达。结果：与模型组相比，中药面膜能够明显缓解痤疮模型大鼠的耳的肿胀率，能够显著减少炎症因子IL-1α、IL-6及
TNF-α的血清水平，显著增加IL-2血清中水平，差异有统计学意义（P ＜0.05）。中药面膜能够明显降低痤疮组织中炎症因
子IL-1α、IL-6及TNF-α的表达，显著增加IL-2的表达，差异有统计学意义（P ＜0.01）。结论：中药面膜具有良好的抗炎
作用且对痤疮模型大鼠具有较好的治疗作用。

Abstract:
Abstract: Objective To explore the therapeutic effect of Chinese herbal mask on acne animal model. Methods 32 rats were
divided into the two groups: the normal control group (n =8) and the modeling group (n =24). The animal model was established
by using Propionibacterium acnes. The model rats were divided into the three groups: the model group, the retinoic acid
group and the drug mask group after successful modeling. The model group were treated with nothing, the retinoic acid group
were treated with 0.1% Vitamin A acid cream, and the drug mask group were treated with Chinese medicine facial mask. The
treatment lasted for 2 weeks. The serum levels of IL-1α,IL-6,TNF-α and IL-2 in each group were measured by enzyme-linked
immunosorbent assay (Elisa).Western Blot was used to detect the expression of IL-1, IL-6, TNF-α and IL-2 in acne tissues
of rats. Results Compared with the model group, the traditional Chinese medicine mask could significantly alleviate the
swelling rate of the ears of the rats with acne model, and could significantly reduce the serum level of the inflammatory factors
IL-1 alpha, IL-6 and TNF- alpha, and significantly increase the level of IL-2 in the serum, the differences were statistically
significant(P ＜0.05). Chinese medicine mask could significantly reduce the expression of inflammatory factors IL-1 alpha, IL-6
and TNF- alpha in acne tissues, and significantly increase the expression of IL-2(P ＜0.05). Conclusion Chinese medicine
facial mask has good anti-inflammatory effect and has a well therapeutic effect on acne model rats.

相似文献/References:

[1]. 埋线美容专栏[J].中国美容医学,2018,(01):0.
　[J].Medical Aesthetics and Beauty,2018,(07):0.
[2]杨 震. 应用透明质酸颏部填充联合A型肉毒毒素咬肌注射重塑面部下1/3轮廓的效果观察[J].中国美容医学,2018,(03):1.
　YANG Zhen. Effect of Hyaluronic Acid Chin Filling Combined with Botulinum Toxin Type A Masseter Muscle Injection to Reconstruct the Facial Contour of the Lower 1/3[J].Medical Aesthetics and Beauty,2018,(07):1.
[3]祝闽辉,张栋梁,叶祥柏,等. 皮肤软组织扩张术埋置注液期并发症危险因素研究[J].中国美容医学,2018,(03):4.
　ZHU Min-hui,ZHANG Dong-liang,YE Xiang-bo,et al. Risk Factors of Complications after Tissue Expasion[J].Medical Aesthetics and Beauty,2018,(07):4.
[4]刘申松,杨永成. 自体脂肪颗粒移植联合假体隆乳术在哺乳后乳腺萎缩整形术中的应用[J].中国美容医学,2018,(03):9.
　LIU Shen-song,YANG Yong-cheng. Application of Autologous Fat Granule Graft Combined with Prosthesis Combined Augmentation Mammoplasty in Breast Reconstruction of Breast Atrophy Patients after Breast-feeding[J].Medical Aesthetics and Beauty,2018,(07):9.
[5]韩 星,胡守舵,陈晓芳,等.自体脂肪颗粒移植促进手部年轻化的临床观察[J].中国美容医学,2018,(03):12.
　HAN Xing,HU Shou-duo,CHEN Xiao-fang,et al. The Effect of Autologous Fat Grafting in Hand Rejuvenation[J].Medical Aesthetics and Beauty,2018,(07):12.
[6]李胜旭,苏映军,杨 宽,等. 封闭负压引流技术在先天性并指分指植皮术中的应用[J].中国美容医学,2018,(03):15.
　LI Sheng-xu,SU Ying-jun,YANG Kuan,et al. Application of Vacuum Sealing Drainage for Skin Graft in Patients with Congenital Syndactyly of the Hand[J].Medical Aesthetics and Beauty,2018,(07):15.
[7]陈 波,路 会,马 力,等. 钝针皮下层扇形注射透明质酸矫正面颊部凹陷[J].中国美容医学,2018,(03):18.
　CHEN Bo,LU Hui,MA Li,et al. Correction of Cheek Depression by Fanshaped Hyaluronic Acid Injection in Subcutaneous Layers with Blunt Needle[J].Medical Aesthetics and Beauty,2018,(07):18.
[8]曾德斌,栗鹏程,邱勋永,等. 不同超薄游离穿支皮瓣修复手部软组织缺损效果比较[J].中国美容医学,2018,(03):21.
　ZENG De-bin,LI Peng-cheng,QIU Xun-yong,et al. Comparison on the Repair Effect of Different Ultrathin Free Perforator Flaps in the Treatment of Patients with Soft Tissue Defect of Hand[J].Medical Aesthetics and Beauty,2018,(07):21.
[9]程 定,崔树英,郑 乐,等. 改道引流联合VSD技术修复会阴部撕裂伤的临床研究[J].中国美容医学,2018,(03):24.
　CHENG Ding,CUI Shu-ying,ZHENG Le,et al. Clinical Study on Diverted Drainage Combined with Vacuum Sealing Drainage Technique to Repair the Laceration of the Perineum[J].Medical Aesthetics and Beauty,2018,(07):24.
[10]李云峰,吴泽勇,黄海华,等. 全厚皮片游离移植矫治儿童足背瘢痕挛缩畸形[J].中国美容医学,2018,(03):27.
　LI Yun-feng,WU Ze-yong,HUANG Hai-hua,et al. Full-thickness Skin Graft for the Treatment of Cicatricial Contracture of the Dorsum of Foot in Children[J].Medical Aesthetics and Beauty,2018,(07):27.
[11]张 丽,陈振平,杨慈航,等. 中药面膜辅助治疗黄褐斑临床疗效Meta分析及用药规律探讨[J].中国美容医学,2020,(3):106.
　ZHANG Li,CHEN Zhen-ping,YANG Ci-hang,et al. Meta-analysis of Therapeutic Effi cacy of TCM Masque for Chloasma AndInvestigation on the Regularity of Prescription Selection and Medicine Use[J].Medical Aesthetics and Beauty,2020,(07):106.

更新日期/Last Update: 2018-09-07