[1]司晨琛,马委委,刘 娟,等. 激光治疗甲真菌病疗效的系统评价[J].中国美容医学,2018,(08):24-32.
　[J].Medical Aesthetics and Beauty,2018,(08):24-32.
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 激光治疗甲真菌病疗效的系统评价
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《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2018年08期
页码:
24-32
栏目:
出版日期:
2018-09-10

文章信息/Info

文章编号:
1008-6455（2018）08-0024-09
作者:
司晨琛; 马委委; 刘 娟; 许 阳; 王大光; 骆 丹; 周炳荣
关键词:
[关键词]甲真菌病; 激光; 单组率; 系统评价
Keywords:
 ; Key words: onychomycosis;  laser;  single rate; systematic review
分类号:
R616.4
文献标志码:
A
摘要:
[摘要]目的：评价激光治疗甲真菌病的疗效。方法：对电子数据库PubMed，Web of science、中国知网、万方数据库、维
普数据库系统检索至2018年1月相关文献并下载。纳入符合标准的激光治疗甲真菌病的随机对照试验及临床自身对照试验，
采用R软件进行Meta分析。结果：共纳入36篇文献，患者1 783例，病甲4 501个。单个率的Meta分析显示：真菌学治愈率达
62%，95%CI(0.52-0.72)。其中，1 064nm Nd:YAG激光治疗甲真菌病的真菌学治愈率为62%，95%CI（0.51-0.73）；CO2激光真
菌学治愈率为67%，95%CI(0.37-0.91)。结论：1 064nmNd:YAG激光和CO2激光治疗甲真菌病有一定的疗效且安全性较高。受纳
入研究质量所限，上述结论可能需要开展进一步的随机对照试验加以验证。

Abstract:
Abstract: Objective To assess the curative effect of laser treatment of onychomycosis. Methods We searched PubMed, Web of
science, China National Knowledge Internet, Wanfang Database, Weipu Database up to January 2018, to collect clinical articles
about the curative effect of laser treatment of onychomycosis. Besides, meta-analysis was performed by R software. Results 36
articles involving 1783 patients and 4501 infected nails were enrolled. The single arm meta-analysis showed that: the mycological
cure rate was 62%,95%CI (0.52-0.72). The mycological cure rate of 1 064nm Nd: YAG laser was 62%,95%CI(0.51-0.73); that of
CO2 laser was 67%,95%CI (0.37-0.91). Conclusion Laser treatment of onychomycosis is effective and safe. Due to the limited
quality of the included studies, the above conclusions may need to be verified by further randomized controlled trials.

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更新日期/Last Update: 2018-10-11