[1]廖俊琳,李 里,陈 碾,等. 不同形状的兔自体软骨组织体内异位移植后吸收与融合的实验研究[J].中国美容医学,2018,(12):121-124.
　LIAO Jun-lin,LI li,CHEN Nian,et al. Experimental Study on Absorption and Fusion of Rabbit Autologous Cartilage withDifferent Shapes after Ectopic Transplantation in Vivo[J].Medical Aesthetics and Beauty,2018,(12):121-124.
点击复制

 不同形状的兔自体软骨组织体内异位移植后吸收与融合的实验研究
()
分享到：

《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2018年12期
页码:
121-124
栏目:
出版日期:
2018-12-20

文章信息/Info

Title:
 Experimental Study on Absorption and Fusion of Rabbit Autologous Cartilage with
Different Shapes after Ectopic Transplantation in Vivo
文章编号:
1008-6455（2018）12-0121-04
作者:
廖俊琳; 李 里; 陈 碾; 尹 瀚; 方卫婷; 周玲聪; 谢红炬
Author(s):
LIAO Jun-lin; LI li; CHEN Nian; YIN Han; FANG Wei-ting; ZHOU Ling-cong; XIE Hong-ju
关键词:
[关键词]自体软骨; 异位移植; 吸收; 融合; 活性
Keywords:
Key words: autologous cartilage;  heterotopic transplantation;  absorption;  fusion;  viablity
分类号:
R329
文献标志码:
A
摘要:

[摘要]目的：观察新西兰大白兔自体颗粒软骨、块状软骨及条状软骨在体内异位移植后的吸收与融合情况。方法：新西兰大
白兔共10只，获取一侧兔耳软骨组织，去除软骨膜后制成1mm×1mm大小颗粒软骨和1cm×1cm大小缝合的软骨块，同时获取第
7、8肋软骨，实验分为颗粒软骨组、块状软骨组和条状软骨组，所有软骨组织埋置于兔背部，术后3个月取材后进行大体观
察、湿重，融合后的软骨组织柔韧度测量，以及组织学观察。结果：术后3个月与术前三种形状的软骨组织湿重对比，差异
无统计学意义。大体观颗粒软骨及耳块状软骨融合成一个整体，外周可见结缔组织纤维膜包裹，并可见新生血管长入，条状
肋软骨未见融合，融合后的颗粒软骨及耳软骨块进行手工压缩和弯曲测量后两者形状未见改变，但融合后的颗粒软骨具备更
良好的形态和柔韧度。HE染色观察可见颗粒软骨组织外周软骨细胞新生以及软骨样增生。结论：自体颗粒软骨、块状软骨及
条状软骨体内异位移植3个月后均未见明显吸收，自体颗粒软骨融合后具备更加良好的外形、柔韧度和活性。

Abstract:

Abstract: Objective The absorption and fusion of autogenous granular cartilage, massive cartilage and stripe cartilage after
heterotopic transplantation were observed in New Zealand white rabbits. Methods One side of rabbit ear cartilages were
obtained from 6 New Zealand white rabbits. After perichondrium was removed, 1mm×1mm diced cartilages and 1cm×1cm
massive cartilages were made and sutured. At the same time, the 7、8th costal cartilage were obtained. The groups divided
into diced cartilage group, massive cartilage group and strip cartilage group. All the cartilage tissues were buried in the back
of the rabbit. The gross morphological observation, wet weight, soft toughness of the cartilage tissue after fusion and histological
observation were observed 3 months after operation. Results Three months after operation, there was no significant difference
in wet weight of three shapes of cartilage before and after operation. In gross morphological observation, diced cartilages and
massive cartilages were fused into a whole, connective tissue fibrous membrane could be seen in the periphery, neovascularization
could be seen, and no fusion could be seen in the striped costal cartilage. The shape of the fused diced cartilage and ear cartilage
was not changed after manual compression and bending measurement. But the diced cartilage after fusion had better morphology
and flexibility. HE staining showed that the peripheral chondrocytes and chondroid hyperplasia were observed. Conclusion
There was no obvious absorption of autologous diced cartilage, massive cartilage and strip cartilage after 3 months of heterotopic
transplantation. The autologous diced cartilage had a better shape, flexibility and viablity after fusion.
更新日期/Last Update: 2019-01-10