[1]华若岳. 重组人表皮生长因子在面部深Ⅱ度烧伤创面修复中的应用研究[J].中国美容医学,2019,(02):36-38.
 HUA Ruo-yue. Application of rhEGF in the Process of Facial Deep Second Degree Burn Wound Repair[J].Medical Aesthetics and Beauty,2019,(02):36-38.
点击复制

 重组人表皮生长因子在面部深Ⅱ度烧伤创面修复中的应用研究
()
分享到:

《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2019年02期
页码:
36-38
栏目:
出版日期:
2019-02-15

文章信息/Info

Title:
 Application of rhEGF in the Process of Facial Deep Second Degree Burn Wound Repair
文章编号:
1008-6455(2019)02-0036-03
作者:
华若岳
Author(s):
HUA Ruo-yue
关键词:
[关键词]重组人表皮生长因子面部深Ⅱ度烧伤创面修复瘢痕疗效
Keywords:
Key words: recombinant human epidermal growth factor(rhEGF) face deep second degree burn wound repair scar curative effect
分类号:
R622
文献标志码:
A
摘要:
[摘要]目的:探讨重组人表皮生长因子(recombinant human epidermal growth factor,rhEGF)在面部深Ⅱ度烧伤创面修
复过程中的应用效果。方法:2016年6月-2018年1月笔者医院收治的面部皮肤深Ⅱ度烧伤患者100例作为研究对象,采用随机
数表法分为观察组和对照组。对照组采用常规治疗,观察组在对照组的基础上使用rhEGF治疗。对比两组创面愈合时间、6个
月后温哥华瘢痕量表(Vancouver scar scale,VSS)评分和疗效。结果:观察组创面完全愈合时间明显低于对照组,差异
有统计学意义(P <0.05)。治疗6个月后,观察组瘢痕色泽、厚度、柔软度和血管分布评分及总分均低于对照组,差异有
统计学意义(P <0.05)。观察组疗效为96.00%明显高于对照组的72.00%,差异有统计学意义(χ2=10.714,P =0.001)。结
论:采用人工合成细胞活性因子rhEGF治疗面部深Ⅱ度烧伤的疗效确切,其可以促进创面愈合,抑制瘢痕生成。

Abstract:
Abstract: Objective To observe the application of recombinant human epidermal growth factor (rhEGF) in the process of facial
deep second degree burn wound repair. Methods From June 2016 to January 2018, 100 patients with deep second degree burn
of facial skin were treated in our hospital. The patients were divided into the observation group and the control group by random
number table method. The control group received routine treatment, while the observation group was treated with rhEGF on
the basis of the control group. The wound healing time, the vancouver scar scale (VSS) score after 6 months and the curative
effect were compared between the two groups. Results The healing time of wounds in the observation group was significantly
lower than that in the control group, the difference was statistically significant(P <0.05). After 6 months of treatment, the scar
color, thickness, softness and vascular distribution score and total score of the observation group were lower than those of the
control group(P <0.05). The curative effect of the observation group was 96.00%, which was significantly higher than that of
the control group (72.00%, χ2=10.714, P =0.001). Conclusion Synthetic cytokine rhEGF is effective in the treatment of facial
deep second degree burn, which can promote wound healing and inhibit scar formation.

相似文献/References:

[1]倪晓静,王 坤. “风筝”皮瓣修复面部皮肤缺损的临床应用[J].中国美容医学,2018,(04):27.
 NI Xiao-jing,WANG Kun. Clinical Application of Kite Flap to Repair Facial Skin Defect[J].Medical Aesthetics and Beauty,2018,(02):27.
[2]姚晓东,吴晓琰,崔晓美,等. 双极射频联合左旋维生素C治疗面部皮肤光老化疗效观察[J].中国美容医学,2018,(07):94.
 YAO Xiao-dong,WU Xiao-yan,CUI Xiao-mei,et al. The Clinical Survey of Bipolar Radiofrequency Combined with L-vitamin C in the Treatment of Facial Skin Photoaging[J].Medical Aesthetics and Beauty,2018,(02):94.
[3]文丽萍,周书帆,邓 映,等. 短波理疗联合强脉冲光治疗面部糖皮质激素依赖性皮炎临床观察[J].中国美容医学,2018,(11):36.
 WEN Li-ping,ZHOU Shu-fan,DENG Ying,et al. Clinical Observation of Desensitization Apparatus Combined with Intense PulsedLight in the Treatment of Facial Glucocorticosteroid-dependent Dermatitis[J].Medical Aesthetics and Beauty,2018,(02):36.
[4]陈 燕,李 生,马 明. 强脉冲光联合长脉宽Nd:YAG激光治疗面部毛细血管扩张症疗效观察[J].中国美容医学,2019,(03):54.
 CHEN Yan,LI Sheng,MA Ming. Therapeutic Effect of Intense Pulsed Light Combined with Long Pulse Width Nd:YAGLaser on Facial Telangiectasia[J].Medical Aesthetics and Beauty,2019,(02):54.
[5]战大川,赵月荣,赵振德,等. bFGF联合自体脂肪移植在面部凹陷性瘢痕治疗中的美容价值研究[J].中国美容医学,2019,(04):116.
 ZHAN Da-chuan,ZHAO Yue-rong,ZHAO Zhen-de,et al. Study on the Cosmetic Value of bFGF Combined with Autologous Fat Transplantationin the Treatment of Facial Depressed Scar[J].Medical Aesthetics and Beauty,2019,(02):116.
[6]何航远,赵小瑜,韩 未,等. 面部皮脂腺囊肿小切口摘除术的诊疗探讨[J].中国美容医学,2019,(04):128.
 HE Hang-yuan,ZHAO Xiao-yu,HAN Wei,et al. Experience in Treatment of Facial Sebaceous Cyst with Small Incision Surgery[J].Medical Aesthetics and Beauty,2019,(02):128.
[7]丛 林,杨蓉娅. 贻贝提取物护理软膏治疗面部敏感性皮肤疗效观察[J].中国美容医学,2019,(05):47.
 CONG Lin,YANG Rong-ya. Clinical Efficacy of Mussel Adhesive Protein Extractive Ointment on Facial Sensitive Skin[J].Medical Aesthetics and Beauty,2019,(02):47.
[8]刘芃祥,王文娟,郝永红,等. 皮肤镜在面部光线性角化病诊断中的应用研究[J].中国美容医学,2019,(05):50.
 LIU Peng-xiang,WANG Wen-juan,HAO Yong-hong,et al. Application of Dermoscopy in the Diagnosis of Facial Actinic Keratosis[J].Medical Aesthetics and Beauty,2019,(02):50.
[9]陈永平,王金河. 点阵铒激光联合羟基乙酸治疗面部痤疮瘢痕临床观察[J].中国美容医学,2019,(06):56.
 CHEN Yong-ping,WANG Jin-he. Clinical Efficacy of Combined Lattice Erbium Laser with Glycolic Acid Treatment of Facial Acne Scar[J].Medical Aesthetics and Beauty,2019,(02):56.
[10]古芝燕,陈晓娟,李俊茹. 不同浓度曲安奈德局部注射联合手术切除治疗面部瘢痕疙瘩[J].中国美容医学,2019,(07):79.
 GU Zhi-yan,CHEN Xiao-juan,LI Jun-ru.Local Injection of Triamcinolone Acetonide with Different Concentrations Combinedwith Surgical Resection for Facial Keloid[J].Medical Aesthetics and Beauty,2019,(02):79.

更新日期/Last Update: 2019-03-06