[1]周锦烽,杨蓊勃,顾延庆,等. 机械牵张对移植皮片挛缩影响的实验研究[J].中国美容医学,2019,(02):83-87.
 ZHOU Jin-feng,YANG Weng-bo,GU Yan-qing,et al. Experimental Study on the Effects of Mechanical Stretch on the Skin Graft Contracture[J].Medical Aesthetics and Beauty,2019,(02):83-87.
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 机械牵张对移植皮片挛缩影响的实验研究
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《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2019年02期
页码:
83-87
栏目:
出版日期:
2019-02-15

文章信息/Info

Title:
 Experimental Study on the Effects of Mechanical Stretch on the Skin Graft Contracture
文章编号:
1008-6455(2019)02-0083-05
作者:
周锦烽1杨蓊勃2顾延庆2郝 超1
Author(s):
ZHOU Jin-feng1YANG Weng-bo2GU Yan-qing2HAO Chao1
关键词:
 [关键词]SD大鼠植皮片机械应力牵张挛缩动物实验
Keywords:
 Key words: SD rats skin graft mechanical stress stretch contracture animal experiment
分类号:
R622
文献标志码:
A
摘要:
[摘要]目的:评估机械牵张对于移植皮片的影响,为改善植皮片术后挛缩寻找新的治疗方法。方法:SPF级SD大鼠24只,雄
性,3月龄,体重300g~330g,随机分为三组,在每只大鼠背部建立两个大小相同的全厚植皮模型,各组大鼠术后随机选取
一皮片,以自制弹性牵张装置分别行纵向、横向及双向牵张,另一皮片为自身对照。牵张2周后测量各治疗组与对照组皮片
的面积、长度、宽度,并计算长宽比。结果:经过2周的机械牵张,各治疗组的植皮片在受力的方向上均变长了,从而造成
了植皮片形态改变和面积的增加。单向牵张组的植皮术在非受力方向的长度较牵张前有所减少,而自身对照组的皮片则无此
改变,说明其长度改变由机械牵张引起,而非术后挛缩引起。结论:初步实验表明,机械牵张可以有效地增加植皮片的长度
与面积,全方位的机械牵张作用尤其明显,这一方法值得进一步的深入研究,从而为植皮片术后挛缩这一难题提供更好的治
疗方法。

Abstract:
Abstract: Objective To evaluate the effect of mechanical stretching on skin graft and to find a new method to improve the
contracture after skin graft. Methods Twenty-four SD rats of SPF grade, male, aged 3 months, weighing 300g to 330g,
were divided into three groups. Two full-thickness skin grafting models of the same size were established in each rat’s back.
One skin graft was randomly selected from each group after operation, and the self-made elastic stretching device was used
for longitudinal, transverse and bidirectional stretching, and the other skin graft was used for self-control. After 2 weeks of
distraction, the area, length and width of the skin of each treatment group and the control group were measured, and the aspect
ratio was calculated. Results After two weeks of mechanical stretching, the skin grafts in each treatment group were lengthened
in the direction of force, resulting in the morphological changes of skin grafts and the increase of the area. The length of skin
graft in unilateral distraction group was less than that before distraction, while the length of skin graft in self-control group
was unchanged, indicating that the length change was caused by mechanical distraction, not by postoperative contracture.
Conclusion Preliminary experiments show that mechanical stretching can effectively increase the length and area of skin graft,
especially the omni-directional mechanical stretching. This method is worthy of further study, so as to provide a better treatment
for contracture after skin graft.

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更新日期/Last Update: 2019-03-07