[1]许 康,唐 金,潘 伟,等. 果酸联合阿达帕林凝胶及罗红霉素胶囊治疗中度痤疮疗效观察[J].中国美容医学,2019,(04):45-47.
 XU Kang,TANG Jin,PAN Wei,et al. The Curative Effect of Alpha-hydeoxy Acid Combine with Adalparine Gel andRoxithromycin Capsule in the Treatment of Moderate Acne[J].Medical Aesthetics and Beauty,2019,(04):45-47.
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 果酸联合阿达帕林凝胶及罗红霉素胶囊治疗中度痤疮疗效观察
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《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2019年04期
页码:
45-47
栏目:
出版日期:
2019-04-15

文章信息/Info

Title:
 The Curative Effect of Alpha-hydeoxy Acid Combine with Adalparine Gel and
Roxithromycin Capsule in the Treatment of Moderate Acne
文章编号:
1008-6455(2019)04-0045-03
作者:
许 康唐 金潘 伟蒋 鹏
Author(s):
XU KangTANG JinPAN WeiJIANG Peng
关键词:
[关键词]痤疮果酸阿达帕林凝胶罗红霉素胶囊YAG激光疗效
Keywords:
Key words: acne alpha-hydeoxy acid adalparine gel roxithromycin capsule YAG laser the curative effec
分类号:
R619+.6
文献标志码:
A
摘要:
[摘要]目的:探究果酸联合阿达帕林凝胶及罗红霉素胶囊治疗中度痤疮的临床疗效。方法:选取2017年1月-2018年3月
笔者医院收治的80例中度痤疮患者,随机分为两组,其中联合组使用果酸联合阿达帕林凝胶外用及口服罗红霉素胶囊
(n =40),激光组行YAG激光治疗(n =40)。观察两组治疗后皮损计数、临床疗效和不良反应发生情况。结果:与治疗前
比较,治疗后两组患者皮损计数均显著下降(P <0.05);治疗后联合组粉刺、丘疹、脓疱等计数显著低于激光组,差异有
统计学意义(P <0.05)。两组患者临床疗效比较,联合组总有效率为92.5%,显著高于YAG激光组的75%,差异有统计学意
义(P <0.05)。联合组面部紧绷感发生率显著高于激光组(P <0.05),而激光组紫癜或点状出血的发生率显著高于联合组
(P <0.05),但两组总不良事件比较,差异无统计学意义(P >0.05)。结论:在中度痤疮治疗中,果酸联合阿达帕林凝胶
及罗红霉素胶囊具有更好的治疗效果,但临床上需根据患者个体情况进行选择。

Abstract:
Abstract: Objective To explore the curative effect of alpha-hydeoxy acid combined with adalparine gel and roxithromycin
capsule in the treatment of moderate acne. Methods From January 2017 to March 2018, 80 patients with moderate acne were
randomly divided into two groups.The combination group was treated with alpha-hydeoxy acid and adapaline gel combine
with roxithromycin capsule (n =40), and the laser group was treated with YAG laser (n =40).The number of skin lesions, clinical
efficacy and adverse reactions were observed after treatment in the two groups. Results After treatment, the number of skin
lesions decreased significantly in both groups(P <0.05), and the number of acne, papules and pustules in the combined group
was significantly lower than that in the laser group(P <0.05).The total effective rate of the combined group was 92.5%, which
was significantly higher than that of the YAG laser group (75%, P <0.05).The incidence of facial tension in the combined group
was significantly higher than that in the laser group(P <0.05), the incidence of purpura or punctate hemorrhage in laser group
was significantly higher than that in combined group(P <0.05). But there was no significant difference in total adverse events
between the two groups(P <0.05). Conclusion In the treatment of moderate acne patients, the combination of alpha-hydeoxy
acid and adalepalin gel and roxithromycin capsule has a better therapeutic effect, but clinical choice should be made according
to the individual situation of the patients.

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更新日期/Last Update: 2019-05-05