[1]邹 筠,袁 华,付荣华,等.普萘洛尔治疗婴幼儿血管瘤时机选择及安全性评估的临床研究[J].中国美容医学,2019,(06):78-79.
　ZOU Yun,YUAN Hua,FU Rong-hua,et al. Clinical Study on Timing and Safety Evaluation of Propranolol in Treatment of Infant Hemangioma[J].Medical Aesthetics and Beauty,2019,(06):78-79.
点击复制

普萘洛尔治疗婴幼儿血管瘤时机选择及安全性评估的临床研究
()
分享到：

《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2019年06期
页码:
78-79
栏目:
出版日期:
2019-06-05

文章信息/Info

Title:
 Clinical Study on Timing and Safety Evaluation of Propranolol in Treatment of Infant Hemangioma
文章编号:
1008-6455（2019）06-0078-03
作者:
邹 筠; 袁 华; 付荣华; 金平亮
Author(s):
ZOU Yun; YUAN Hua; FU Rong-hua; JIN Ping-liang
关键词:
[关键词]普萘洛尔; 婴幼儿血管瘤; 时机选择; 安全性; 口服; 生长发育
Keywords:
Key words: propranolol;  infantile hemangioma;  time choice;  safety;  oral administration;  growth and development
分类号:
R732.2
文献标志码:
A
摘要:
[摘要]目的：观察普萘洛尔口服治疗婴幼儿血管瘤时机选择及安全性的临床研究。方法：选取血管瘤患儿60例，按年龄分
组，口服药物1.5mg/kg·d，分2次服药，持续6个月～1年不等。评价其治疗效果，并统计患儿停药后1年生长发育情况与正
常同龄幼儿发育状况对比。结果：1岁以内患儿用该方法治疗疗效显著，1岁以上的患儿显效不明显。其中有3例（小于3个
月的婴幼儿）因服药后血糖偏低而停止治疗。57例血管瘤患儿身高、体重、头围按“2006年世界卫生组织0～10岁儿童生长
标准”表对比均在生长范围内。结论：口服普萘洛尔治疗婴幼儿血管瘤在1岁内治疗安全有效，不良反应少，患儿耐受好，
对于小于3个月患儿用药需谨慎观察，通过分析该药对患儿的生长发育不产生任何影响，是一种有效的治疗婴幼儿血管瘤的
方法。

Abstract:
Abstract: Objective To observe the clinical study of timing and safety of propranolol oral treatment for infant hemangioma.
Methods Sixty children with hemangioma were use as study group by using propranolol, grouped by age, and at a dose of
1.5mg/(kg?d), by dividing into 2 times with continuous medication from 6 months to 1 year. To evaluate the therapeutic effect,
and to compare the growth and development of the children one year after drug withdrawal with that of the normal children of
the same age. Results The therapeutic effect of this method was significant in children under 1 year old, but not in those over
1 years old. Three of them (less than 3 months old) stopped treatment because of hypoglycemia. The height, weight and head
circumference of 57 children with hemangioma were in the range of growth according to“the World Health Organization (WHO)
growth Standard for Children aged 0-10 years 2006”. Conclusion Oral propranolol treatment of infant hemangioma within
1 year safe and effective, and the adverse effects are minimal. Care should be taken to observe the medication for children
younger than 3 months. By analyzing the effect of this drug on the growth and development of children, it is an effective
method to treat infant hemangioma.

相似文献/References:

[1]姚天华,Krishna Regmi,杜婧婷,等. Bax在普萘洛尔诱导人血管瘤内皮细胞凋亡中的作用[J].中国美容医学,2019,(01):100.
　YAO Tian-hua,KRISHNA Regmi,DU Jing-ting,et al. The Effect of Bax on Propranolo Induced Hemangioma Endothelial Cell Apoptosis[J].Medical Aesthetics and Beauty,2019,(06):100.
[2]徐筑秋 综述,杨晓楠 祁佐良 审校. 西罗莫司治疗卡波西形血管内皮瘤的研究进展[J].中国美容医学,2019,(08):155.
　XU Zhu-qiu,YANG Xiao-nan,QI Zuo-liang. Research Progress of Sirolimus in Kaposiform Hemangioendothelioma Treatment[J].Medical Aesthetics and Beauty,2019,(06):155.
[3] 魏 娜,赵东红,李 江. 普萘洛尔口服联合复方倍他米松注射治疗婴幼儿血管瘤的护理配合探讨[J].中国美容医学,2021,(7):165.
　 WEI Na,ZHAO Dong-Hong,LI Jiang. Nursing Experience of Infantile Hemangioma by Intralesional Injection of PropranololCombined with Compound Betamethasone[J].Medical Aesthetics and Beauty,2021,(06):165.
[4]孙 恒,倪志福,屈振繁.两种给药方式治疗婴幼儿血管瘤疗效对比研究[J].中国美容医学,2021,(12):86.
　SUN Heng,NI Zhi-fu,QU Zhen-fan.Clinical Comparative Study of Two Drug Administration Methods for Treatment of Infantile Hemangiomas[J].Medical Aesthetics and Beauty,2021,(06):86.
[5]高倩倩 综述,霍 然审校.婴幼儿血管瘤治疗效果评分系统的研究进展[J].中国美容医学,2022,(7):172.
　GAO Qianqian,HUO Ran.Research Progress in Scoring the Therapeutic Effects of Infantile Hemangiomas[J].Medical Aesthetics and Beauty,2022,(06):172.
[6]陈远征 陈昱岐 综述,白 南 审校.口服普萘洛尔治疗婴幼儿血管瘤临床应用新进展[J].中国美容医学,2023,(11):189.[doi:10.15909/j.cnki.cn61-1347/r.005980]
　CHEN Yuanzheng,CHEN Yuqi,BAI Nan.New Progress in Clinical Application of Oral Propranolol in the Treatment of Infantile Hemangioma[J].Medical Aesthetics and Beauty,2023,(06):189.[doi:10.15909/j.cnki.cn61-1347/r.005980]
[7] 张宇飞,刘晋灵,王 博,等. 普萘洛尔联合其他治疗措施治疗婴幼儿血管瘤有效率的网状Meta分析[J].中国美容医学,2020,(5):27.
　 ZHANG Yu-fei,LIU Jin-ling,WANG Bo,et al. Effi cient of Propranolol Combined with Other Therapy in the Treatment of InfantileHemangiomas:A Network Meta-analysis[J].Medical Aesthetics and Beauty,2020,(06):27.

更新日期/Last Update: 2019-07-03