[1]宿 斌,杨 晶,李香梅,等. 超脉冲CO2点阵激光联合碱性成纤维细胞生长因子软膏治疗痤疮后凹陷性瘢痕疗效研究[J].中国美容医学,2019,(10):63-65.
 SU Bin,YANG Jing,LI Xiang-mei,et al. Effect of Co2 Dot Array Laser Combined with Alkaline Fibroblast Growth FactorOintment in the Treatment of Acne Concave Scar[J].Medical Aesthetics and Beauty,2019,(10):63-65.
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 超脉冲CO2点阵激光联合碱性成纤维细胞生长因子软膏治疗痤疮后凹陷性瘢痕疗效研究
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《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2019年10期
页码:
63-65
栏目:
出版日期:
2019-10-05

文章信息/Info

Title:
 Effect of Co2 Dot Array Laser Combined with Alkaline Fibroblast Growth Factor
Ointment in the Treatment of Acne Concave Scar
文章编号:
1008-6455(2019)10-0063-03
作者:
 宿 斌1杨 晶2李香梅2黄国钦3王家璧4
Author(s):
SU Bin1YANG Jing2LI Xiang-mei2HUANG Guo-qin3WANG Jia-bi4
关键词:
 [关键词]痤疮后凹陷性瘢痕超脉冲CO2点阵激光碱性成纤维细胞生长因子美容效果
Keywords:
 Key words: acne depressed scar dot matrix CO2 laser basic fibroblast growth factor cosmetic effect
分类号:
R619+.6
文献标志码:
A
摘要:
[摘要]目的:探究超脉冲CO2点阵激光联合碱性成纤维细胞生长因子(bFGF)软膏治疗痤疮凹陷性瘢痕临床疗效,为患者的
治疗提供参考。方法:选择笔者医院2016年3月-2018年3月收治的寻常性痤疮后凹陷性瘢痕患者98例,按照入院ID将其分为
观察组50例和对照组48例,其中对照组采用超脉冲CO2点阵激光治疗,观察组在对照组基础上联合bFGF软膏进行治疗,每月1
次,连续治疗3次,治疗完成1个月后,分析两组患者临床疗效、VISIA检测结果、VSS评分及不良反应发生情况。结果:治疗
后,观察组总有效率为94.0%,明显高于对照组(85.4%),两组比较差异有统计学意义(P <0.05);观察组的VISIA检测评
分明显高于对照组(P <0.05);治疗前,两组患者VSS评分比较差异无统计学意义(P >0.05),治疗后,观察组VSS评分为
(5.9±0.7)分,明显低于对照组(6.4±0.9)分,差异有统计学意义(P <0.05);观察组患者治疗后不良反应发生率为
4.0%,明显低于对照组(14.6%,P <0.05)。结论:超脉冲CO2点阵激光联合bFGF软膏治疗寻常性痤疮后凹陷性瘢痕具有良
好的临床效果,安全性较好,能有效改善患者面部美观,值得在临床中推广。

Abstract:
Abstract: Objective To explore the clinical effect of acne scars of acne vulgaris with dot matrix CO2 laser combined with basic
fibroblast growth factor (bFGF) ointment, and provide reference for the treatment of patients. Methods 98 patients with acne
scars of acne vulgaris admitted to our hospital from March 2016 to March 2018 were selected as the study subjects. According
to the patient admission ID, they were divided into observation group 50 cases and control group 48 cases. The patients were
treated with dot matrix CO2 laser. The observation group was treated with bFGF ointment on the basis of the control group.
Once a month, after 3 months of continuous treatment, the clinical efficacy, VISIA test results, VSS score and adverse reactions
were analyzed. Results After treatment, the total effective rate of the observation group was 94.0%, which was significantly
higher than that of the control group (85.4%). The difference between the two groups was statistically significant (P <0.05). The
VISIA test score of the observation group was significantly higher than that of the control group (P <0.05). Before treatment,
there was no significant difference in VSS score between the two groups (P >0.05). After treatment, the VSS score of the
observation group was (5.9±0.7), which was significantly lower than that of the control group (6.4±0.9). The difference between
the two groups was statistically significant (P <0.05). The incidence of adverse reactions in the observation group was 4.0%,
which was significantly lower than that in the control group (14.6%, P <0.05). Conclusion Dot matrix CO2 laser combined
with bFGF ointment has a good clinical effect in treating acne scars of acne vulgaris, it has good safety and can effectively
improve the facial appearance of patients. It is worthy of widespread promotion in the clinic.

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更新日期/Last Update: 2019-11-06