[1] 高明菊,杨 名,吴炳为,等. A型肉毒毒素联合透明质酸治疗眉间纹效果探讨[J].中国美容医学,2020,(11):51-53.
　 GAO Ming-ju,YANG Ming,WU Bing-wei,et al. Effect of Botulinum Toxin Type A Combined with Hyaluronic Acid Injection in theTreatment of Glabellar Lines[J].Medical Aesthetics and Beauty,2020,(11):51-53.
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 A型肉毒毒素联合透明质酸治疗眉间纹效果探讨
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《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2020年11期
页码:
51-53
栏目:
出版日期:
2020-11-10

文章信息/Info

Title:
 Effect of Botulinum Toxin Type A Combined with Hyaluronic Acid Injection in the
Treatment of Glabellar Lines
文章编号:
1008-6455（2020）11-0051-03
作者:
 高明菊; 杨 名; 吴炳为; 白新平
Author(s):
 GAO Ming-ju; YANG Ming; WU Bing-wei; BAI Xin-ping
关键词:
 [关键词]眉间纹; 透明质酸; A型肉毒毒素; 注射; 维持效果; 复发
Keywords:
 Key words: glabellar lines;  hyaluronic acid;  botulinum toxin type A;  injection;  maintenance effect;  recurrence
分类号:
R622
文献标志码:
A
摘要:
[摘要]目的：研究注射A型肉毒毒素联合透明质酸（Hyaluronic acid，HA）填充术治疗眉间纹的临床效果。方法：选择2017
年1月-2018年11月共96例于笔者医院治疗眉间纹的就医者，随机分为观察组和对照组。对照组应用A型肉毒毒素治疗，观察
组在A型肉毒毒素注射前行HA填充术治疗，观察比较两组治疗效果，比较效果持续时间、皱纹评分、复发率和满意度。
结果：观察组持续效果显著优于对照组，差异有统计学意义（P ＜0.05）。观察组术后的皱纹评分为（0.69±0.41）
分，低于对照组的（1.27±0.59）分，差异有统计学意义（P ＜0.05）。观察组复发率为4.17%，低于对照组的
18.75%，差异有统计学意义（P ＜0.05）。观察组满意度评分为（3.19±1.15）分，高于对照组的（2.54±1.03）分，差异
有统计学意义（P＜0.05）。结论：HA填充术联合A型肉毒毒素注射治疗眉间纹疗效确切，安全性高，具有较高的临床应用价值。

Abstract:
Abstract: Objective To study the clinical effect of injection of botulinum toxin type A combined with hyaluronic acid (HA)
injection in the treatment of glabellar lines. Methods A total of 96 patients between January 2017 and November 2018 were
randomly divided into the observation group and the control group. The control group was treated with botulinum toxin type
A, and the observation group was treated with hyaluronic acid fi lling before the botulinum toxin type A. The therapeutic
effects, the duration, wrinkle score, recurrence rate and satisfaction score in the two groups were compared. Results
The continuous effect of the observation group was significantly better than that of the control group, the difference
was statistically significant(P ＜0.05). The postoperative wrinkle score of the observation group was (0.69±0.41)points,
which was lower than that in the control group[(1.27±0.59) points, P ＜0.05]. The recurrence rate in the observation group
was 4.17%, which was lower than that in the control group (18.75%, P ＜0.05). The satisfaction score in the observation group
was (3.19±1.15)points, higher than that in the control group[(2.54±1.03)points, P ＜0.05]. Conclusion Hyaluronic acid fi lling
combined with botulinum toxin type A for the treatment of glabellar lines is effective and safe, and has high clinical value.

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更新日期/Last Update: 2020-11-24