瘢痕-毛囊炎型反常性痤疮的临床及组织病理学特征研究<br />-《中国美容医学》

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Title:: Study on Clinical and Histopathological Characteristics of Scar Folliculitis-type
Abnormal Acne

文章编号:: 1008-6455（2021）01-0066-04

作者:: 眭洪峰; 邹俊仙; 周梅华

Author(s):: SUI Hong-feng; ZOU Jun-xian; ZHOU Mei-hua

关键词:: [关键词]反常性痤疮; 瘢痕-毛囊炎型; 经典型; 临床特征; 病理学特征

Keywords:: Key words: acne inversa; scarring folliculitis; regular type; clinical characteristics; histopathological characteristics

分类号:: R758.73+3

文献标志码:: A

摘要:: [摘要]目的：探讨瘢痕-毛囊炎型反常性痤疮和经典型反常性痤疮的临床和组织病理特征并进行比较，进一步揭示反常性痤
疮的临床特点及发病机制。方法：纳入2017年6月-2019年6月就诊于南通大学附属丹阳医院的20例反常性痤疮患者为观察
组，6名健康者为对照组。记录患者临床和穿刺病理信息后进行统计学分析。结果：共计纳入了20例16～25岁反常性痤疮
患者进行观察，其中瘢痕-毛囊炎型11例（55.0%）、经典型9例（45.0%）。瘢痕-毛囊炎型患者臀部和/或腹股沟受累比例
（81.8% vs 22.2%，P =0.002）、化学物品接触史（81.8%vs22.2%，P =0.002）和职业暴露史（45.5%vs0.0%，P =0.038）显著
高于经典型患者。瘢痕-毛囊炎型患者病理学可有多种表现，而经典型则仅有表皮色素沉着和囊泡周围炎。瘢痕-毛囊炎型患
者皮脂腺面积显著小于对照组。结论：瘢痕-毛囊炎型反常性痤疮可有多种病变类型、病理学改变，并且皮脂腺显著萎缩，
以腹股沟和臀部受累为特征，可有相关化学物质接触史等。

Abstract:: Abstract: Objective To explore the clinical and histopathological characteristics of scar-folliculitis-type abnormal acne and
classic abnormal acne, and to reveal the clinical characteristics and pathogenesis of abnormal acne. Methods Twenty patients
with abnormal acne who were treated in our hospital from June 2017 to June 2019 and 6 healthy controls without known
skin diseases were prospectively included. Statistical analysis was performed after recording patient clinical information and
puncture pathology information. Results Twenty patients aged 16-25 years were included in the study, including 11 cases of
scarring folliculitis type (55.0%) and 9 cases of regular type (45.0%). The incidence of gluteal and/or groin involvement (81.8%
vs 22.2%, P = 0.002), chemical exposure (81.8% vs 22.2%, P =0.002) and occupational exposure (45.5% vs 0.0%, P =0.038) in
patients with scarring folliculitis type were significantly higher than those in patients with regular type. There are multi-types of
pathological manifestations in patients with scarring folliculitis type,while in the classic type,only epidermal hyperpigmentation
and perifollicular inflammation are found. The area of sebaceous glands in patients with scarring folliculitis type was
significantly smaller than that in the control group. Conclusion The scarring folliculitis type in acne inversa in Chinese population
could be characterized by depressed scars, double-ended comedones, epidermal cysts and had high proportion of smokers, or
occupational exposure as well as diminished sebaceous gland.

《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

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