[1] 周琦琪,韩祥祯,张文静,等. 全唾液法分析糖尿病及牙周炎伴牙列缺损患者行种植义齿修复的临床效果[J].中国美容医学,2021,(1):104-108.
　 ZHOU Qi-qi,HAN Xiang-zhen,ZHANG Wen-jing,et al. Analysis of the Clinical Effect of Complete Saliva Analysis on the Repair of DentalImplant Denture in Patients with Diabetes and Periodontitis with Dentition Defect[J].Medical Aesthetics and Beauty,2021,(1):104-108.
点击复制

 全唾液法分析糖尿病及牙周炎伴牙列缺损患者行种植义齿修复
的临床效果
()
分享到：

《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2021年1期
页码:
104-108
栏目:
出版日期:
2021-01-10

文章信息/Info

Title:
 Analysis of the Clinical Effect of Complete Saliva Analysis on the Repair of Dental
Implant Denture in Patients with Diabetes and Periodontitis with Dentition Defect
文章编号:
1008-6455（2021）01-0104-05
作者:
 周琦琪; 韩祥祯; 张文静; 崔 杰
Author(s):
 ZHOU Qi-qi;  HAN Xiang-zhen;  ZHANG Wen-jing;  CUI Jie
关键词:
 [关键词]全唾液; 糖尿病; 慢性牙周炎; 种植术; 种植体稳定性
Keywords:
 Key words: whole unstimulated saliva; diabetes mellitus;  chronic periodontitis;  implantation; implant stability quotient
分类号:
R782.12
文献标志码:
A
摘要:
[摘要]目的：探究糖尿病及牙周炎伴牙列缺损患者种植治疗的预后疗效，以此作为该类患者种植治疗术前评估，为提高种
植成功率提供参考依据。方法：分别于种植前和种植后4周、12周与24周收集2型糖尿病患者组、牙周炎患者组以及对照组
患者唾液,记录探诊深度、测量种植体稳定性，实验ELISA法检测唾液中的IL-1β与TNF-α，荧光定量PCR测量TF、Pg、Td、
Fn的相对SQ值变化。结果：2型糖尿病患者组、牙周炎患者组的ISQ值与对照组比较无统计学差异(P ＜0.05)，组内显示对比
ISQ值在12周时明显高于术中，提示稳定性呈增加趋势，具有统计学意义(P ＜0.05)；两实验组的唾液中IL-1β和TNF-α的含
量高于对照组，并有统计学意义(P ＜0.05)，且两组随时间推移，唾液中IL-1β和TNF-α的含量均降低，具有统计学意义(P
＜0.05)；Tf、Pg、Fn 的相对SQ值四次检查结果逐渐减少，差异有统计学意义（P ＜0.05），Td相对SQ值四次检查结果无显
著性差异（P ＞0.05）。结论：菌斑控制良好的牙周炎患者与血糖控制良好的糖尿病患者，均可取得与正常患者一致的种植
初期稳定性，且炎性因子和细菌水平持续降低，提示两者均可以取得较好的种植预后效果。

Abstract:
Abstract: Objective To explore the prognosis of patients with diabetes and periodontitis with dentition defect,and to provide
reference for improving the success rate of implantation. Methods Saliva of patients with type 2 diabetes mellitus, periodontitis
and control group were collected before implantation and 4 weeks, 12 weeks and 24 weeks after implantation, respectively. The
depth of exploration was recorded and the stability of implantation was measured. IL-1B and TNF-α in saliva were detected by
experimental ELISA, and the changes of TF,Pg,Td,Fn were measured by RT-PCR. Results There was no significant difference
in ISQ between the two groups (P ＜0.05). The results showed that the ISQ of the two groups was significantly higher than that
of the control group at 12 weeks, suggesting that the stability was increasing (P ＜0.05). The contents of IL-1β and TNF -α in
saliva of the two experimental groups were higher than that of the control group (P ＜0.05), and the two groups were statistically
significant (P ＜0.05) .The contents of IL-1β and TNF-α in saliva were all decreased (P ＜0.05).The relative SQ values of TF,
PG and FN were gradually decreased (P ＜0.05), and the difference was statistically significant (P ＜0.05). Conclusion In
a short period of time, periodontitis patients with good plaque control and diabetes patients with good blood glucose control
can achieve the same implant stability as normal patients, and the inflammatory inheritance and bacterial level are reduced,
suggesting that they can achieve better implant prognosis.

相似文献/References:

[1]张冀北,王峻岭,李 慧,等. rh-bFGF联合局部外用胰岛素治疗糖尿病深Ⅱ度烧伤创面的临床观察[J].中国美容医学,2019,(02):32.
　ZHANG Ji-bei,WANG Jun-ling,LI Hui,et al. Clinical Observation of rh-bFGF Combined with Topical Insulin in the Treatment ofDeep Second Degree Burn of Diabetes[J].Medical Aesthetics and Beauty,2019,(1):32.
[2]吴宪成,凌 彬,张周良. 和田地区牙源性颌面部间隙感染临床病例回顾性分析[J].中国美容医学,2019,(02):132.
　WU Xian-cheng,LING Bin,ZHANG Zhou-liang. Odontogenic Maxillofacial Space Infections at Hetian: A Retrospective Clinical Study[J].Medical Aesthetics and Beauty,2019,(1):132.
[3]张春玲,陈 露,赵 伟,等. 丹银海绵对糖尿病大鼠皮肤溃疡创面愈合的影响[J].中国美容医学,2020,(3):71.
　ZHANG Chun-ling,CHEN Lu,ZHAO Wei,et al. Effect of Danyin Sponge on Skin Ulcer Wound Healing in Diabetic Rats[J].Medical Aesthetics and Beauty,2020,(1):71.
[4] 赵超然,王湘琦,熊爱兵. 低氘水联合富血小板血浆对糖尿病大鼠胰岛细胞的保护作用及TGF-1表达的影响[J].中国美容医学,2021,(6):101.
　 ZHAO Chao-ran,WANG Xiang-qi,XIONG Ai-bing. Effects of Deuterium-depleted Water Combined with Platelet-rich Plasma on IsletCell Protection and TGF-β1 Expression in Diabetic Rats[J].Medical Aesthetics and Beauty,2021,(1):101.
[5]雷 宇,周忠志,兰宏伟,等.象皮生肌膏对糖尿病皮肤溃疡修复的效果及其机理探究[J].中国美容医学,2022,(1):89.
　LEI Yu,ZHOU Zhongzhi,LAN Hongwei,et al.Effect of Xiangpi Shengji Ointment on IL-6 and TNF- in Diabetic Skin Ulcer[J].Medical Aesthetics and Beauty,2022,(1):89.
[6]杨荣阁,张振锋,孙兴华.调营和卫益气养血法治疗血虚型糖尿病性皮肤瘙痒症的临床应用[J].中国美容医学,2022,(5):114.
　YANG Rongge,ZHANG Zhenfeng,SUN Xinghua.Clinical Application of Harmonizing Yingfen and Weifen and Reinforcing Qi and Nourishing Blood Method in the Treatment of Blood Deficiency Syndrome Diabetic Skin Pruritus[J].Medical Aesthetics and Beauty,2022,(1):114.
[7]陈文娇 综述,刘 毅 审校.糖尿病对脂肪干细胞分化能力的影响[J].中国美容医学,2022,(5):176.
　CHEN Wenjiao,LIU Yi.Effect of Diabetes Mellitus on Differentiation of Adipose Derived Stem Cells[J].Medical Aesthetics and Beauty,2022,(1):176.
[8]刘 惠,陈艳艳.iRoot SP 单尖法根管充填联合牙周基础治疗糖尿病患者慢性根尖周炎疗效观察[J].中国美容医学,2024,(3):139.
　LIU Hui,CHEN Yanyan.Curative Effect of iRoot SP Single Apex Root Canal Filling in Patients with Diabetes Mellitus and Chronic Periapical Periodontitis[J].Medical Aesthetics and Beauty,2024,(1):139.
[9]王 一 龚思宇 综述,姜笃银 审校.脂肪干细胞及其衍生物促慢性创面愈合的研究进展[J].中国美容医学,2024,(4):179.
　WANG Yi,GONG Siyu,JIANG Duyin.Research Progress of Adipose-derived Stem Cells and Their Derivatives Promoting Chronic Wound Healing[J].Medical Aesthetics and Beauty,2024,(1):179.

更新日期/Last Update: 2021-02-02