[1] 王秋锋,梁启胜,程向阳,等. 整形美容手术中右美托咪定的应用对患者心脑血管系统的影响研究[J].中国美容医学,2021,(5):25-28.
  WANG Qiu-feng,LIANG Qi-sheng,CHENG Xiang-yang,et al. Effect of Dexmedetomidine on Cardiovascular and Cerebrovascular System inPlastic Surgery[J].Medical Aesthetics and Beauty,2021,(5):25-28.
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 整形美容手术中右美托咪定的应用对患者心脑血管系统的影响研究
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《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2021年5期
页码:
25-28
栏目:
出版日期:
2021-05-10

文章信息/Info

Title:
 Effect of Dexmedetomidine on Cardiovascular and Cerebrovascular System in
Plastic Surgery
文章编号:
1008-6455(2021)05-0025-04
作者:
 王秋锋1梁启胜2程向阳2蔡 宁1梁东锋1
Author(s):
 WANG Qiu-feng1LIANG Qi-sheng2CHENG Xiang-yang2CAI Ning1LIANG Dong-feng1
关键词:
 [关键词]右美托咪定心脑血管系统血压心率心动过速整形美容手术呼吸抑制
Keywords:
 Key words: dexmedetomidine cardiovascular and cerebrovascular system blood pressure heart rate tachycardia plasticsurgery respiratory depression
分类号:
R622
文献标志码:
A
摘要:
[摘要]目的:探讨整形美容手术中右美托咪定的应用对患者心脑血管系统的影响。方法:选取2019年1月-2020年5月在笔者
医院进行整形美容手术178例患者为研究对象,随机数字法分为两组,两组在术中均实施局部麻醉,两组均静脉推注1μg/kg
的芬太尼,局部麻醉药物为浓度0.5%的利多卡因、1:100 000的肾上腺素,对照组联合应用生理盐水,研究组联合应用
右美托咪定,对比右美托咪定的应用对术中高血压、心动过速发生的影响。结果:两组手术时间比较差异无统计学意义
(P >0.05)。但研究组的芬太尼、咪达唑仑用量均少于对照组,差异有统计学意义(P<0.05)。对照组T2、T3时间的HR快
于研究组,RR慢于研究组,MAP高于研究组,差异有统计学意义(P <0.05)。两组低血压、心动过缓的发生率比较差异无统
计学意义(P>0.05)。但研究组高血压、心动过速及呼吸抑制的发生率低于对照组,差异有统计学意义(P <0.05)。研究
组苏醒时间、清醒时间均短于对照组,差异有统计学意义(P <0.05)。结论:在整形美容手术中,应用右美托咪定能够更
好地稳定患者的心率及血压,防止其过度波动引起不良事件的发生,值得临床应用。

Abstract:
Abstract: Objective To investigate the effect of dexmedetomidine on cardiovascular and cerebrovascular system in plastic
surgery. Methods From January 2019 to May 2020, 178 patients undergoing plastic and aesthetic surgery in our hospital
were selected as the study objects. Randomly divided into two groups, the two groups were given local anesthesia during the
operation, both groups were given intravenous injection of 1μg/kg fentanyl, the local anesthetic was 0.5% lidocaine and 1:100 000
epinephrine. The control group was given normal saline, the study group was given dexmedetomidine. And the effects of
dexmedetomidine on intraoperative hypertension and tachycardia were compared. Results There was no significant difference
in operation time between the two groups (P >0.05). But the dosage of fentanyl and midazolam in the study group was less than
those in the control group, the differences were statistically significant (P <0.05). HR at T2 and T3 in the control group were faster
than those in the study group, RR were slower than those in the study group, and MAP were higher than those in the study
group (P <0.05). There was no significant difference in the incidence of hypotension and bradycardia between the two
groups (P >0.05). But the incidence of hypertension, tachycardia and respiratory depression in the study group were lower
than those in the control group (P <0.05). The recovery time and awake time in the study group were shorter than those in the
control group (P <0.05). Conclusion In plastic surgery, dexmedetomidine can better stabilize the heart rate and blood pressure
of patients, prevent the occurrence of adverse events caused by excessive fluctuations, which is worthy of clinical application.

相似文献/References:

[1] 马 茜,白 雪,王倩钰,等. 低剂量右美托咪定复合丙泊酚联合舒芬太尼在面部整形术中的应用效果分析[J].中国美容医学,2021,(4):66.
  MA Qian,BAI Xue,WANG Qian-yu,et al. Application Effect of Low-dose Dexmedetomidine Combined with Propofol andSufentanil in Facial Plastic Surgery[J].Medical Aesthetics and Beauty,2021,(5):66.

更新日期/Last Update: 2021-06-08