[1] 李 琳,肖 佳,赵爱杰,等. 皮肤针叩刺联合苍肤止痒酊治疗神经性皮炎疗效观察[J].中国美容医学,2021,(8):111-114.
　 LI Lin,XIAO Jia,ZHAO Ai-jie,et al. Observation on the Therapeutic Effect of Skin Acupuncture Combined with CangfuAntipruritic Tincture in Neurodermatitis[J].Medical Aesthetics and Beauty,2021,(8):111-114.
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《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2021年8期
页码:
111-114
栏目:
出版日期:
2021-08-10

文章信息/Info

Title:
 Observation on the Therapeutic Effect of Skin Acupuncture Combined with Cangfu
Antipruritic Tincture in Neurodermatitis
文章编号:
1008-6455(2021)08-0111-04
作者:
 李 琳1; 肖 佳1; 赵爱杰1; 杨晓丽1; 李 伟2
Author(s):
 LI Lin1; XIAO Jia1; ZHAO Ai-jie1; YANG Xiao-li1; LI Wei2
关键词:
 [关键词]神经性皮炎; 皮肤针叩刺; 苍肤止痒酊; 炎症反应; β-EP; SP; 5-HT
Keywords:
 Key words:neurodermatitis; skin acupuncture; cangfu antipruritic tincture;  inflammation reaction;  β-EP;  SP; 5-HT
分类号:
R758.3＋2
文献标志码:
A
摘要:
[摘要]目的：探究皮肤针叩刺联合苍肤止痒酊治疗神经性皮炎的疗效。方法：选取笔者医院2018年1月-2019年9月收治的165
例神经性皮炎患者为研究对象，按照随机数字表法分为三组，每组55例。对照1组给予常规西医治疗，对照2组在常规西医
治疗基础上给予皮肤针叩刺，观察组给予皮肤针叩刺联合苍肤止痒酊。治疗4周为1个疗程，比较三组治疗前后血清炎性因子
[肿瘤坏死因子-α（TNF-α）、白介素-8（IL-8）、白介素-6（IL-6）]、瘙痒介质[β-内啡肽（β-EP）、P物质（SP）、
5-羟色胺（5-HT）]、疼痛（VAS）评分、皮肤病生活质量（DIQL）量表评分及不良反应发生情况。结果：治疗4周后，总有
效率观察组高于对照1组和对照2组，对照2组高于对照1组（P ＜0.05）；三组VAS、DIQL评分以及血清TNF-α、IL-8、IL-6、
β-EP、SP、5-HT水平均低于治疗前，且观察组低于对照1组与对照2组，对照2组低于对照1组（P ＜0.05）；三组不良反应
发生率比较无统计学差异（P ＞0.05）。结论：皮肤针叩刺联合苍肤止痒酊治疗神经性皮炎，可明显降低血清炎性因子、
β-EP、SP、5-HT水平，缓解疼痛程度，提高治疗效果及患者生活质量，值得临床推广应用。

Abstract:
Abstract: Objective To explore the curative effect of skin acupuncture combined with Cangfu antipruritic tincture in
neurodermatitis. Methods A total of 165 patients with neurodermatitis admitted in our hospital from January 2018 to
September 2019 were selected as the research object, and they were divided into three groups according to the random number
table method, 55 cases each. The control group 1 was given conventional western medicine treatment, the control group 2
was given skin acupuncture on the basis of conventional western medicine treatment, and the observation group was given
skin acupuncture combined with Cangfu antipruritic tincture. Treatment for 4 weeks as a course of treatment, comparing the
serum inflammatory factors [tumor necrosis factor-α (TNF-α), interleukin-8 (IL-8), interleukin-6 (IL-6)], pruritus mediators
[β-endorphin (β-EP), substance P (SP), 5-hydroxytryptamine (5-HT)], pain (VAS) score, dermatological quality of life (DIQL)
scale score before and after treatment and adverse reactions in the three groups. Results After 4 weeks of treatment: the total
effective rate in the observation group was higher than that in the control group 1 and the control group 2, and the control
group 2 was higher than the control group 1 (P ＜0.05). The low VAS, DIQL scores and serum levels of TNF-α, IL-8, IL-
6, β-EP, SP and 5-HT in the three groups were lower than before treatment, and the observation group was lower than the
control group 1 and the control group 2, and the control group 2 was lower than the control group 1 (P ＜0.05). There was
no statistical difference in the incidence of adverse reactions among the three groups (P ＞0.05). Conclusion The treatment
of neurodermatitis with skin acupuncture combined with Cangfu antipruritic tincture can significantly reduce the levels of
serum inflammatory factors, β-EP, SP, 5-HT and improve the symptoms of skin lesions, relieve the degree of pain, improve the
treatment effect and the quality of life of patients, and is worthy of clinical promotion and application.
更新日期/Last Update: 2021-09-10