[1]马 璐,王晓培,杨 鑫,等.保乳术联合术后放疗治疗乳腺导管内癌的美学效果及对VEGF-C、TGF-β1水平的影响[J].中国美容医学,2022,(7):38-41.
 MA Lu,WANG Xiaopei,YANG Xin,et al.Aesthetic Effect of Breast-conserving Surgery Combined with Postoperative Radiotherapy in the Treatment of Ductal Carcinoma in Situ and Its Inflfluences on VEGF-C and TGF-β1 Levels[J].Medical Aesthetics and Beauty,2022,(7):38-41.
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保乳术联合术后放疗治疗乳腺导管内癌的美学效果及对VEGF-C、TGF-β1水平的影响
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《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2022年7期
页码:
38-41
栏目:
出版日期:
2022-07-10

文章信息/Info

Title:
Aesthetic Effect of Breast-conserving Surgery Combined with Postoperative Radiotherapy in the Treatment of Ductal Carcinoma in Situ and Its Inflfluences on VEGF-C and TGF-β1 Levels
文章编号:
1008-6455(2022)07-0038-03
作者:
马 璐王晓培杨 鑫肖 丽游紫萱刘 韬
(成都中医药大学附属医院乳腺外科 四川 成都 610072)
Author(s):
MA LuWANG XiaopeiYANG XinXIAO LiYOU ZixuanLIU Tao
(Department of Breast Surgery, Affiliated Hospital of Chengdu University of Traditional Chinese Medicine,Chengdu 610072,Sichuan,China)
关键词:
保乳术放疗乳腺导管内癌美学效果血管内皮生长因子C转化生长因子β1
Keywords:
Times New Roman" color: rgb(35 31 32) font-size: 9.5pt">breast-conserving surgery radiotherapy ductal carcinoma in situ (DCIS) aesthetic effect vascular endothelial growth factor-C (VEGF-C) transforming growth factor-β font-family: "Times New Roman" color: rgb(35 31 32)"> 1 Times New Roman" color: rgb(35 31 32) font-size: 9.5pt"> (TGF-β font-family: "Times New Roman" color: rgb(35 31 32)"> 1 Times New Roman" color: rgb(35 31 32) font-size: 9.5pt">)
分类号:
R737.9
文献标志码:
A
摘要:
目的:探究保乳术联合术后放疗治疗乳腺导管内癌(Ductal carcinoma in situ,DCIS)的美学效果及对血浆血管内皮生长因子C(Vascular endothlial growth factor-C,VEGF-C)、转化生长因子β1(Transforming growth factor-β1,TGF-β1)水平的影响。方法:选取2017年6月-2019年8月笔者医院收治的104例DCIS患者为研究对象,根据患者意愿分为保乳组(52例)和联合放疗组(52例),保乳组采用保乳术进行治疗,联合放疗组在保乳组基础上辅助放疗,比较两组美学效果、血浆VEGF-C和TGF-β1水平及近1年内局部复发及转移情况。结果:两组美学优良率、局部复发率和转移率比较差异均无统计学意义(P>0.05)。联合放疗组术后血浆VEGF-C、TGF-β1水平均显著低于保乳组,差异有统计学意义(P<0.05)。结论:保乳术联合术后放疗治疗乳腺导管内癌可显著降低血浆VEGF-C和TGF-β1水平,且术后美学效果与预后良好。

Abstract:
Objective To explore the aesthetic effect of breast-conserving surgery combined with postoperative radiotherapy in the treatment of ductal carcinoma in situ (DCIS) and its influences on levels of plasma vascular endothlial growth factor-C (VEGF-C) and transforming growth factor-β1 (TGF-β1).Methods A total of 104 DCIS patients admitted to the hospital between June 2017 and August 2019 were enrolled as the research objects. According to their willingness, they were divided into the breast-conserving group (breast-conserving surgery) and the combined radiotherapy group (postoperative radiotherapy on basis of breast-conserving group), 52 cases in each group. The cosmetic effect, levels of plasma VEGF-C and TGF-β1, local recurrence rate and metastasis rate within the past year were compared between the two groups. Results There was no significant difference in aesthetic excellence rate, local recurrence rate and metastasis rate between the two groups (P>0.05). Postoperative plasma VEGF-C and TGF-β1 levels in the combined radiotherapy group were significantly lower than the breast conserving group, the differences were statistically significant (P<0.05). Conclusion Breast-conserving surgery combined with postoperative radiotherapy for DCIS can significantly reduce plasma VEGF-C and TGF-β1 level, and the postoperative aesthetic effect and prognosis are good.

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备注/Memo

备注/Memo:
基金项目:四川省中医药科学技术研究专项项目(编号:2016Q015)
更新日期/Last Update: 2022-07-22