[1]王 娇,余 曦,吴姁怿,等.富血小板血浆联合高压氧治疗慢性难愈合创面的疗效探讨[J].中国美容医学,2022,(7):59-62.
 WANG Jiao,YU Xi,WU Xuyi,et al.Effect of Platelet-rich Plasma Combined with Hyperbaric Oxygen Therapy in the Treatment of Chronic Refractory Wounds[J].Medical Aesthetics and Beauty,2022,(7):59-62.
点击复制

富血小板血浆联合高压氧治疗慢性难愈合创面的疗效探讨()
分享到:

《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2022年7期
页码:
59-62
栏目:
出版日期:
2022-07-10

文章信息/Info

Title:
Effect of Platelet-rich Plasma Combined with Hyperbaric Oxygen Therapy in the Treatment of Chronic Refractory Wounds
文章编号:
1008-6455(2022)07-0059-04
作者:
王 娇余 曦吴姁怿李艾娟曾敬茹罗 姣
(四川大学华西医院康复医学中心 四川 成都 611100 )
Author(s):
WANG JiaoYU XiWU Xuyi LI AijuanZENG JingruLUO Jiao
(Rehabilitation Medicine Center,West China Hospital,Sichuan University,Chengdu 611100,Sichuan,China)
关键词:
富血小板血浆高压氧治疗慢性难愈合创面美学效果瘢痕
Keywords:
platelet-rich plasma(PRP) hyperbaric oxygen therapy(HBOT) chronic refractory wounds cosmetic effect
分类号:
R622
文献标志码:
A
摘要:
目的:分析富血小板血浆(Platelet-rich plasma,PRP)联合高压氧治疗(Hyperbaric oxygen therapy,HBOT)在慢性难愈合创面中的应用效果。方法:选取2019年1月-2021年7月笔者医院收治的慢性难愈合创面患者91例作为研究对象,随机分为观察组(n=46)和对照组(n=45)。对照组给予常规治疗和PRP治疗,观察组在对照组基础上联合HBOT,治疗1个月后比较两组临床疗效,使用Bates-Jensen伤口评估量表(Bates-Jensen wound assessment tool,BWAT)和压疮愈合评分(Pressure ulcer scale for healing,PUSH)比较两组创面愈合情况,使用温哥华瘢痕量表(Vancouver scar scale,VSS)和日常生活能力评定量表(Activities of daily living,ADL)比较美学效果以及生活能力情况。结果:观察组临床总有效率为95.65%高于对照组的82.22%,差异有统计学意义(P<0.05)。治疗后不同时间观察组BWAT评分低于对照组,差异有统计学意义(P<0.05)。治疗后观察组PUSH各维度评分和VSS评分均较对照组降低,且ADL较对照组升高,差异有统计学意义(P<0.05)。结论:富血小板血浆联合高压氧治疗慢性难愈合创面疗效较好,有利于改善PUSH评分促进创面愈合,提高创面美学效果并改善患者生活能力。
Abstract:
Objective To analyze the application effect of platelet-rich plasma (PRP) combined with hyperbaric oxygen therapy (HBOT) in the treatment of chronic refractory wounds. Methods 91 patients with chronic refractory wounds treated in the hospital between January 2019 and July 2021 were selected as the research subjects, and they were randomly divided into the observation group (n=46) and the control group (n=45). The control group was given conventional treatment and PRP treatment, and the observation group was combined with HBOT on the basis of the control group. After 1 month of treatment, the clinical efficacy of the two groups was compared, and Bates-Jensen wound assessment tool (BWAT) and Pressure ulcer scale for healing (PUSH) were used to compare the wound healing of the two groups of patients. Vancouver scar scale (VSS) and Activities of daily living (ADL) were adopted to compare the cosmetic effect and living ability. Results The clinical effective rate of in the observation group was 95.65% higher than that in the control group(82.22%), the difference was statistically significant (P<0.05). BWAT score of the observation group was lower than that of the control group at different time after treatment (P<0.05). After treatment, the PUSH score and VSS score of the observation group were lower than those of the control group, and ADL was higher than that of the control group (P<0.05). Conclusion PRP combined with HBOT has a good efficacy on chronic refractory wounds. It is beneficial to improving PUSH scores, promoting wound healing, enhancing the cosmetic effect of wounds and improving the living ability of patients.

相似文献/References:

[1]陈 健,谢包根,黄永新,等. 富血小板血浆联合清创术治疗难愈性创面的疗效观察[J].中国美容医学,2018,(04):11.
 CHEN Jian,XIE Bao-gen,HUANG Yong-xin,et al. Effect of the Platelet Rich Plasma Combined with Debridement in the Treatment of Refractory Wounds[J].Medical Aesthetics and Beauty,2018,(7):11.
[2]崔晓美,丁晓东,陈晓明,等.微针疗法联合PRP治疗痤疮凹陷性瘢痕疗效分析[J].中国美容医学,2018,(10):27.
 CUI Xiao-mei,DING Xiao-dong,CHEN Xiao-ming,et al.Clinical Application and Experience of Microacupuncture Combined with PRP forTreatment of Acne Depression Scar[J].Medical Aesthetics and Beauty,2018,(7):27.
[3]朱旭冉,刘林嶓,李广帅,等. 颗粒脂肪联合PRP及Nanofat治疗面部凹陷的疗效观察[J].中国美容医学,2018,(12):31.
 ZHU Xu-ran,LIU Lin-bo,LI Guang-shuai,et al. A Preliminary Study on the Effect of Granule Fat Combined with PRP and Nanofat to Reshape the Facial Contour[J].Medical Aesthetics and Beauty,2018,(7):31.
[4]张琼玲,刘 清,余银霞. 毛发移植联合富血小板血浆注射在雄激素性秃发患者治疗中的应用分析[J].中国美容医学,2018,(12):60.
 ZHANG Qiong-ling,LIU Qing,YU Yin-xia.The Value of Hair Transplantation Combined with Platelet-Rich Plasma in the Treatment of Androgen Alopecia[J].Medical Aesthetics and Beauty,2018,(7):60.
[5]李 凯,秦 巍,周 明,等. 自体脂肪颗粒结合富血小板血浆(PRP)移植在面部年轻化治疗中的应用研究[J].中国美容医学,2019,(12):17.
 LI Kai,QIN Wei,ZHOU Ming,et al. Application of Autogenous Fat Granule Combined with Platelet-rich Plasma (PRP)Transplantation in the Treatment of Facial Rejuvenation[J].Medical Aesthetics and Beauty,2019,(7):17.
[6]陈 航,杨景军,魏子人,等. 复合皮移植技术与富血小板血浆对烧伤后大面积瘢痕整复患者血清炎症因子水平及美观度的影响[J].中国美容医学,2020,(2):44.
 CHEN Hang,YANG Jing-jun,WEI Zi-ren,et al. Effect of Composite Skin Transplantation and Platelet-rich Plasma on the Level ofSerum Infl ammatory Factors and Aesthetic Degree in Patients with Large Area Scarafter Burn[J].Medical Aesthetics and Beauty,2020,(7):44.
[7] 徐 旻,吕 君,陈尚周,等. 超脉冲CO2点阵激光联合PRP治疗面部痤疮凹陷性瘢痕疗效分析[J].中国美容医学,2020,(5):41.
  XU Min,LV Jun,CHEN Shang-zhou,et al. Clinical Analysis of Super Pulse CO2 Lattice Laser Combined with PRP in theTreatment of Atrophic Acne Scar[J].Medical Aesthetics and Beauty,2020,(7):41.
[8] 王凤兰,刘 雷. 自体脂肪结合富血小板血浆注射应用于面部年轻化中的效果分析[J].中国美容医学,2020,(5):86.
  WANG Feng-lan,LIU Lei. Analysis on Effect of Autologous Fat Combined with Platelet-rich Plasma Injection onFacial Rejuvenation[J].Medical Aesthetics and Beauty,2020,(7):86.
[9] 管晓玉 纪 覃 吴 灿 综述,白 南 审校. C02点阵激光治疗皮肤创伤性瘢痕的临床应用及研究进展[J].中国美容医学,2020,(7):169.
  GUAN Xiao-yu,JI Tan,WU Can,et al. Clinical Application and Research Progress of CO2 Fractional Laser in the Treatmentof Traumatic Skin Scar:A Systematic Review of Literature[J].Medical Aesthetics and Beauty,2020,(7):169.
[10] 辛增桃,田 朦,靳林昊,等. 纳米脂肪联合PRP注射治疗增生性瘢痕[J].中国美容医学,2020,(10):69.
  XIN Zeng-tao,TIAN Meng,JIN Lin-Hao,et al. Therapeutic Effect of Nanofat Combined with PRP Injection in the Treatment ofHypertrophic Scar[J].Medical Aesthetics and Beauty,2020,(7):69.

更新日期/Last Update: 2022-07-26