[1]罗标益 张 怡 谢志敏 李青青 综述,叶兴东 审校.激光辅助药物输送治疗白癜风临床研究进展[J].中国美容医学,2023,(10):195-197.[doi:10.15909/j.cnki.cn61-1347/r.005915]
　LUO Biaoyi,ZHANG Yi,XIE Zhimin,et al.Research Progress of Laser-assisted Drug Delivery in the Treatment of Vitiligo[J].Medical Aesthetics and Beauty,2023,(10):195-197.[doi:10.15909/j.cnki.cn61-1347/r.005915]
点击复制

激光辅助药物输送治疗白癜风临床研究进展()
分享到：

《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2023年10期
页码:
195-197
栏目:
出版日期:
2023-10-10

文章信息/Info

Title:
Research Progress of Laser-assisted Drug Delivery in the Treatment of Vitiligo
文章编号:
1008-6455（2023）10-0195-03
作者:
罗标益1 张 怡1 谢志敏2 李青青1 综述; 叶兴东1; 2 审校
(1.广州医科大学皮肤病研究所皮肤科 广东 广州 510095 ;2.广州市皮肤病防治所皮肤科 广东 广州 510095 )
Author(s):
LUO Biaoyi1 ; ZHANG Yi1 ; XIE Zhimin2 ; LI Qingqing1 ; YE Xingdong1; 2
(1.Department of Dermatology,Institute of Dermatology,Guangzhou Medical University, Guangzhou 510095,Guangdong,China; 2.Department of Dermatology,Guangzhou Institute of Dermatology,Guangzhou 510095,Guangdong,China)
关键词:
白癜风; 激光辅助药物输送; 剥脱性点阵激光; 外用药物; 治疗
Keywords:
vitiligo;  laser-assisted drug delivery;  ablative fractional laser;  topical medication;  treatment
分类号:
R758.4+ 1
DOI:
10.15909/j.cnki.cn61-1347/r.005915
文献标志码:
A
摘要:
白癜风是一种色素脱失性疾病，发病机制尚不明确。激光辅助药物输送作为一种新型给药方法和联合疗法，能够有效增 加药物渗透吸收和促进黑素细胞迁移，促进复色，从而成为白癜风的治疗手段之一应用于临床。在激光的选择上，首选剥脱性 点阵激光，辅助输送的外用药物有糖皮质激素、钙调神经磷酸酶抑制剂、5-氟尿嘧啶和维生素D3衍生物等，这一疗法具有良好 的安全性和疗效性，在临床上具有良好的应用前景。本文就激光辅助药物输送治疗白癜风的作用机制和应用进展进行阐述。
Abstract:
Vitiligo is a depigmentation disease, and the pathogenesis is not clear. As a new drug delivery method and combination therapy, laser-assisted drug delivery can eff ectively increase drug penetration and absorption, promote melanocyte migration, and promote repigmentation, thus becoming one of the treatment methods for vitiligo in clinical practice. In the choice of laser, the fi rst choice is ablative fractional laser, and the topical drugs assisted delivery are glucocorticoids, calcineurin inhibitors, 5-fl uorouracil and vitamin D3 derivatives. This therapy has good safety and effi cacy, and has a good application prospect in clinical practice. This article reviews the mechanism and application progress of laser-assisted drug delivery in the treatment of vitiligo.

相似文献/References:

[1]陈 雪 综述,吴 皞 徐漫远 闵仲生审校. 火针治疗在损容性皮肤病中的应用[J].中国美容医学,2018,(04):155.
　CHEN Xue,WU Hao,XU Man-yuan,et al. The Application of Fire-Needle Therapy in Cosmetic Dermatosis[J].Medical Aesthetics and Beauty,2018,(10):155.
[2]郑羽宇,杨书平,戴 婷,等. 皮肤原位再生医疗技术联合微针导入治疗白癜风疗效观察[J].中国美容医学,2018,(07):97.
　ZHENG Yu-yu,YANG Shu-ping,DAI Ting,et al. The Clinical Observation of Skin Situ Regeneration Medical Technique Combined with Microneedle Introduction Technology in the Treatment of Vitiligo[J].Medical Aesthetics and Beauty,2018,(10):97.
[3]薛 梅,张德利,刁庆春,等. 丹参酚酸B对过氧化氢引起的黑素细胞凋亡的保护作用研究[J].中国美容医学,2019,(06):64.
　XUE Mei,ZHANG De-li,DIAO Qing-chun,et al. Study on Magnesium Tanshinoate B Alleviated H2O2-induced Apoptosis in Human Epidermal Melanocytes[J].Medical Aesthetics and Beauty,2019,(10):64.
[4]赵莲英,刘冬青,刘文利. 308nm准分子激光联合驱白巴布斯片对面部白癜风患者的美容修复效果研究[J].中国美容医学,2020,(2):60.
　ZHAO Lian-ying,LIU Dong-qing,LIU Wen-li. Study on the Cosmetic Repair Effect in Patients with Facial Vitiligo by Using 308nmExcimer Laser Combined with Qubaibasi Tablets[J].Medical Aesthetics and Beauty,2020,(10):60.
[5] 吉 津,章若画,严 炯,等. 他克莫司联合复方甘草酸苷片对白癜风稳定期患者血清Th1/Th2型细胞因子水平的影响[J].中国美容医学,2020,(5):48.
　 JI Jin,ZHANG Ruo-hua,YAN Jiong,et al. The Effect of Tacrolimus Combined with Glycyrrhizic Acid Tablet on the Level of Th1/Th2 Cytokines in Patients with Stable Vitiligo[J].Medical Aesthetics and Beauty,2020,(10):48.
[6] 杨芝香,康定华. 窄谱中波紫外线对白癜风患者血清维生素D水平的影响[J].中国美容医学,2020,(6):42.
　 YANG Zhi-xiang,KANG Ding-hua. Influence of Narrow-band Ultraviolet B on Serum Vitamin D Levels forPatients with Vitiligo[J].Medical Aesthetics and Beauty,2020,(10):42.
[7] 王云颖 综述,康晓静 审校. 自噬在免疫性皮肤病中的研究进展[J].中国美容医学,2020,(7):180.
　 WANG Yun-ying,KANG Xiao-jing. Emerging Progress of Autophagy in Autoimmune Skin Diseases[J].Medical Aesthetics and Beauty,2020,(10):180.
[8] 丁 钰,黄忠奎,胡秀玲. 自身免疫性甲状腺疾病患者血清25-（OH）D表达水平与白癜风的相关性分析[J].中国美容医学,2020,(10):111.
　 DING Yu,HUANG Zhong-kui,HU Xiu-ling. Correlation between Serum 25-(OH)D Expression Level and Vitiligo in Patients withAutoimmune Thyroid Disease[J].Medical Aesthetics and Beauty,2020,(10):111.
[9] 林士伟,魏茗蕾,孔 静. 晕痣患者中白癜风发生状况及其危险因素分析[J].中国美容医学,2020,(12):40.
　 LIN Shi-wei,WEI Ming-lei,KONG Jing. Analysis of the Occurrence of Vitiligo and its Risk Factors in Patients with Syncope[J].Medical Aesthetics and Beauty,2020,(10):40.
[10] 任 虎. 毫火针辅助308nm准分子光联合他克莫司软膏对白癜风患者疗效及免疫功能的影响[J].中国美容医学,2021,(3):102.
　 REN Hu. Effect of Millifire Needle Assisted 308nm Excimer Laser Combine with TacrolimusOintment on Immune Function of Patients with Vitiligo[J].Medical Aesthetics and Beauty,2021,(10):102.

更新日期/Last Update: 2023-11-13