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《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:

期数:

2024年4期

页码:

25-29

栏目:

出版日期:

2024-04-10

文章信息/Info

Title:

Effects of Silver Ion Dressing Combined with Compound Polymyxin B Ointment in the Treatment of Deep Second-Degree Burn Infectious Wounds

文章编号:

1008-6455（2024）04-0025-04

作者:

马雅宁; 赵 鹏; 孟素玉; 徐文虎; 胡荔男; 王 康

(邢台市第五医院烧伤整形科 河北 邢台 054000 )

Author(s):

MA Yaning;  ZHAO Peng;  MENG Suyu;  XU Wenhu;  HU Linan;  WANG Kang

(Department of Burn and Plastic Surgery, Xingtai City Fifth Hospital, Xingtai 054000, Hebei, China)

关键词:

银离子敷料; 复方多粘菌素B软膏; 深Ⅱ度烧伤感染性创面; 炎性因子; 瘢痕 [

Keywords:

silver ion dressing;  compound polymyxin b ointment;  deep second-degree burn infectious wounds;  infl ammatory factors;  scar

分类号:

R644

文献标志码:

A

摘要:

目的：探讨银离子敷料联合复方多粘菌素B软膏治疗深Ⅱ度烧伤感染性创面的疗效。方法：选取149例深Ⅱ度烧伤感染 性创面患者，依照乱数表法分为观察组（n=75例）和对照组（n=74例），对照组给予复方多粘菌素B软膏治疗，观察组在对 照组基础上加用银离子敷料治疗。统计比较两组创面恢复相关指标、创面疼痛程度、血清炎性因子和疼痛介质水平、临床疗 效及瘢痕情况。结果：治疗后，观察组感染控制时间、住院时间、创面愈合时间均短于对照组（P＜0.05），治疗21 d后的 创面愈合率高于对照组（P＜0.05）。观察组治疗后各时间点疼痛评分均低于对照组（P＜0.05）；治疗21 d后，观察组血清 C 反应蛋白、白介素-6、神经肽Y、前列腺素E2水平均低于对照组（P＜0.05），创面愈合总有效率高于对照组（P＜0.05）； 创面愈合后6个月，观察组温哥华瘢痕量表各评分及总分均低于对照组（P＜0.05）。结论：银离子敷料联合复方多粘菌素B 软膏治疗深Ⅱ度烧伤感染性创面能促进创面愈合，减轻创面疼痛程度，并能有效抑制血清炎性因子、疼痛介质水平，减轻创 面瘢痕程度，提升创面美学效果。

Abstract:

Objective To explore the eff ects of silver ion dressing and compound polymyxin B ointment in the treatment of burn infectious wounds. Methods A total of 149 patients with deep partial-thickness burn infection wounds were selected and divided into observation group (n=75) and control group (n=74) according to the random number table method. The control group was treated with compound polymyxin B ointment, and the observation group was treated with silver ion dressing on the basis of the control group. The wound recovery related indicators, wound pain degree, serum infl ammatory factors and pain mediators levels, clinical effi cacy and scar condition were statistically compared between the two groups. Results After treatment, the infection control time, hospitalization time, and wound healing time in the observation group were shorter than those in the control group (P ＜0.05), and the wound healing rate after 21 days of treatment was higher than that in the control group (P＜0.05). The pain scores of the observation group were lower than those of the control group at each time point after treatment (P＜0.05). After 21 days of treatment, the serum levels of C-reactive protein, interleukin-6, neuropeptide Y, and prostaglandin E2 in the observation group were lower than those in the control group (P＜0.05), and the total eff ective rate of wound healing was higher than that in the control group (P ＜0.05). Six months after wound healing, each score and total score of Vancouver Scar Scale in the observation group were lower than those in the control group (P＜0.05). Conclusion Silver ion dressing combined with compound polymyxin B ointment in the treatment of deep partial-thickness burn infected wounds can promote wound healing, reduce wound pain, eff ectively inhibit the levels of serum infl ammatory factors and pain mediators, reduce wound scar, and improve wound aesthetic eff ect.

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更新日期/Last Update: 2024-04-08