[1] 于 浩 姜爱莉 李 敏 付步芳 综述,王召旭审校. 《整形手术用交联透明质酸钠凝胶》标准中质量控制方法的研究进展[J].中国美容医学,2020,(12):185-189.
　 YU Hao,JIANG Ai-li,LI Min,et al. Research Progress of Quality Control Methods in the Standard of Cross-linkedSodium Hyaluronate Gel for Plastic Surgery[J].Medical Aesthetics and Beauty,2020,(12):185-189.
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 《整形手术用交联透明质酸钠凝胶》标准中质量控制方法的研究进展
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《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2020年12期
页码:
185-189
栏目:
出版日期:
2020-12-10

文章信息/Info

Title:
 Research Progress of Quality Control Methods in the Standard of Cross-linked
Sodium Hyaluronate Gel for Plastic Surgery
文章编号:
1008-6455（2020）12-0185-05
作者:
 于 浩1; 2 姜爱莉1 李 敏1; 2 付步芳2 综述; 王召旭2审校
Author(s):
 YU Hao1; 2; JIANG Ai-li1; LI Min1; 2; FU Bu-fang2; WANG Zhao-xu2
关键词:
 [关键词]透明质酸; 交联透明质酸钠凝胶; 注射整形; 质量控制
Keywords:
 Key words:hyaluronic acid; cross-linked sodium hyaluronate gel;  injection shaping;  quality control
分类号:
R622
文献标志码:
A
摘要:
[摘要]透明质酸（Hyaluronic acid，HA）是人体组织成分之一，广泛存在于人体皮肤、软骨组织、韧带以及眼睛玻璃体
中，具有良好的生物相容性、亲水性、粘弹性及低免疫原性。生物工程生产的交联透明质酸钠凝胶具有相似的生物学特性，
是目前最常用的注射微整手术填充材料之一。该文首先回顾了注射整形行业的发展历史，同时分析了交联透明质酸钠凝胶在
整形行业的应用，包括面部除皱、隆鼻颏、瘢痕修复等部分，重点阐述了整形手术用交联透明质酸钠凝胶质量控制的方法，
包括交联剂残留量、透明质酸钠含量、溶胀度、蛋白质含量、重金属含量以及分子量等。结合国内外交联透明质酸钠凝胶的
研究动态，提出了今后的发展前景。

Abstract:
Abstract:Hyaluronic acid (HA) is one of the components of human tissues. It is widely present in human skin, cartilage tissues,
ligaments, and vitreous eyes.It has good biocompatibility,hydrophilicity, viscoelasticity,and low immunogenicity.The crosslinked
sodium hyaluronate gel produced by bioengineering has similar biological characteristics and is currently one of the most
commonly used filling materials for injection microsurgery.This article first reviews the development history of the injection
plastic surgery industry,and analyzes the application of cross-linked sodium hyaluronate gel in the plastic surgery industry,
including facial wrinkle removal, rhinoplasty, scar repair and other parts, focusing on the use of plastic surgery The method
of quality control of sodium hyaluronate gel includes the residual amount of crosslinking agent, sodium hyaluronate content,
swelling degree, protein content, heavy metal content and molecular weight. Combining the research development of crosslinked
sodium hyaluronate gel at home and abroad, the future development prospects are proposed.

相似文献/References:

[1] 夏 炜 黄 莹 综述,郭树忠 审校. 透明质酸填充剂的物理生物特性与临床应用[J].中国美容医学,2020,(6):45.
　 XIA Wei,HUANG Ying,GUO Shu-zhong. Rheological Properties and Clinical Application of Hyaluronic Acid Injectable Filler[J].Medical Aesthetics and Beauty,2020,(12):45.
[2] 李 霞 王玉玲 综述,郭学平审校. 透明质酸在外用传递系统中的应用研究进展[J].中国美容医学,2021,(1):177.
　[J].Medical Aesthetics and Beauty,2021,(12):177.

更新日期/Last Update: 2021-01-08