[1]荆 雪 闫琪浩 宁小娜 马天源 谢义德 综述,刘富伟 审校.纳米脂肪在皮肤修复中的应用与机制[J].中国美容医学,2023,(9):191-196.[doi:10.15909/j.cnki.cn61-1347/r.005867]
　JING Xue,YAN Qihao,NING Xiaona,et al.Review on the Application and Mechanism of Nanofat in Skin Repair[J].Medical Aesthetics and Beauty,2023,(9):191-196.[doi:10.15909/j.cnki.cn61-1347/r.005867]
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纳米脂肪在皮肤修复中的应用与机制()
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《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2023年9期
页码:
191-196
栏目:
出版日期:
2023-09-10

文章信息/Info

Title:
Review on the Application and Mechanism of Nanofat in Skin Repair
文章编号:
1008-6455（2023）09-0191-06
作者:
荆 雪1 闫琪浩2 宁小娜3 马天源4 谢义德5 综述; 刘富伟4 审校
(1.空军军医大学 陕西 西安 710032 2.福州恩喜医疗美容医院门诊部 福建 福州 350000 3.空军军医大学唐都医院眼科 陕西 西安 710032 4.空军军医大学口腔医院颌面外科 陕西 西安 710032 5.福建医科大学附属协和医院整形外科 福建 福 州 350000 )
Author(s):
JING Xue1 ; YAN Qihao2 ; NING Xiaona3 ; Ma Tianyuan4 ; Xie Yide5 ; LIU Fuwei4
(1.Military Medical University of Air Force,Xian 710032,Shaanxi,China 2.Outpatient Department,Fuzhou Enxi Medical Cosmetology Hospital,Fuzhou 350000,Fujian,China 3.Department of Ophthalmology,Tangdu Hospital,Air Force Military Medical University,Xian 710032,Shaanxi,China 4.Department of Maxillofacial Surgery,Stomatology Hospital of Air Force Military Medical University,Xian 710032,Shaanxi,China 5.Department of Plastic Surgery,Union Hospital Affi liated to Fujian Medical University,Fuzhou 350000,Fujian,China)
关键词:
纳米脂肪; 皮肤修复; 年轻化治疗; 瘢痕; 干细胞; 创面; 脂肪来源干细胞; 生长因子; 外泌体; 血管形成
Keywords:
nano-fat skin repair rejuvenation therapy scar stem cells wound surface adipose-derived stem cells growth factor exosome angiogenesis
分类号:
R622+ .9
DOI:
10.15909/j.cnki.cn61-1347/r.005867
文献标志码:
A
摘要:
纳米脂肪是将抽取出的颗粒脂肪机械乳化提纯后留下的微小颗粒组织。一方面，机械乳化过程去除了移植后难以存活的含 有大油滴的成熟脂肪细胞，可减轻移植后的炎症反应与吸收；另一方面，随着针对纳米脂肪成分及作用机制研究的不断深入，人 们发现纳米脂肪中含有大量脂肪来源干细胞、血管内皮细胞、免疫细胞，以及细胞外基质与生长因子等，这些成分具有促进组织 再生的可能。尤其是在皮肤修复领域，纳米脂肪不单能起充填作用，还能促进创面愈合，并可抑制修复后瘢痕，改善皮肤质地与 色泽，甚至对毛发等皮肤附属器具有促进修复作用。本文就纳米脂肪在皮肤修复中的综合作用及可能机制展开综述。
Abstract:
Nanofat is the tiny particle tissue left after mechanical emulsifi cation and purifi cation of the extracted fat particles. On the one hand, the mechanical emulsifi cation process removes the mature adipocytes containing large oil droplets that are diffi cult to survive after transplantation, which can reduce the infl ammatory reaction and absorption after transplantation. On the other hand, with the deepening of research on the composition and mechanism of nanofat, it has been found that nano-fat contains a large number of adipose-derived stem cells (ADSCs), vascular endothelial cells, immune cells, extracellular matrix and growth factors, which may promote tissue regeneration. Especially in the fi eld of skin repair, nanofat can not only play a fi lling role, but also promote wound healing, inhibit scar after repair, improve skin texture and color, and even promote skin accessories such as hair. This article reviews the comprehensive eff ect and possible mechanism of Nanofat in skin repair.

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更新日期/Last Update: 2023-10-16