[1] 方建强,马 杰,于晓锋. 低浓度5-氟尿嘧啶联合曲安奈德注射治疗瘢痕疙瘩疗效分析[J].中国美容医学,2021,(4):26-28.
　 FANG Jian-qiang,Ma Jie,Yu Xiao-feng. Analysis of Low Concentration 5-fluorouracil Combined with Triamcinolone Injectionin the Treatment of Keloid[J].Medical Aesthetics and Beauty,2021,(4):26-28.
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 低浓度5-氟尿嘧啶联合曲安奈德注射治疗瘢痕疙瘩疗效分析
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《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2021年4期
页码:
26-28
栏目:
出版日期:
2021-04-10

文章信息/Info

Title:
 Analysis of Low Concentration 5-fluorouracil Combined with Triamcinolone Injection
in the Treatment of Keloid
文章编号:
1008-6455（2021）04-0026-03
作者:
 方建强; 马 杰; 于晓锋
Author(s):
 FANG Jian-qiang;  Ma Jie;  Yu Xiao-feng
关键词:
 [关键词]瘢痕疙瘩; 5-氟尿嘧啶; 曲安奈德; 美学效果
Keywords:
 Key words:keloid;  5-fluorouracil;  triamcinolone;  aesthetic effect
分类号:
R619+.6
文献标志码:
A
摘要:
[摘要]目的：研究低浓度5-氟尿嘧啶联合曲安奈德注射治疗瘢痕疙瘩的美学效果。方法：选取2016年2月-2018年2月于笔者
医院接受治疗的100例瘢痕疙瘩患者为研究对象，采用随机数字表法分为联合组和对照组，每组50例。对照组用曲安奈德注
射液治疗，联合组用低浓度5-氟尿嘧啶联合曲安奈德注射液治疗，1周1次，持续治疗4周后，观察比较两组临床疗效、瘢痕
评分及不良反应。结果：联合组总有效率（78.00%）明显高于对照组（58.00%）(P ＜0.05)；治疗前，两组瘢痕评分比较差
异无统计学意义（P ＞0.05）；治疗后，两组中瘢痕评分与治疗前比较显著下降(P ＜0.05)，对照组瘢痕评分明显著高于联
合组(P ＜0.05)；两组治疗过程中均未出现严重不良反应。结论：低浓度5-氟尿嘧啶联合曲安奈德注射治疗瘢痕疙瘩疗效确
切，有助于促进瘢痕软化，提高美容效果，且不会增加副反应，安全性好。

Abstract:
Abstract: Objective To investigate the aesthetic effect of low concentration 5-fluorouracil combined with triamcinolone
injection in the treatment of keloid. Methods 100 patients with keloid in our hospital from February 2016 to February 2018
were enrolled, and randomly divided in two groups, each with 50 cases. Control group received the triamcinolone injection,
while combined group received low concentration 5-fluorouracil combined with triamcinolone injection. Once a week,
after 4 weeks of continuous treatment, the clinical effect, scar score and adverse reactions were observed and compared
between the two groups. Results The total efficacy of combined group was higher than that of control group (78.00%
vs 58.00%, P ＜0.05). The scar score had no difference between groups before treatment (P ＞0.05), which was decreased
in both groups after treatment, and was lower in combined group than in control group (P ＜0.05). There were no serious
adverse reactions in the combined group and the control group. Conclusion Low concentration 5-fluorouracil combined with
triamcinolone injection can effectively and safely make scar soft and improve the cosmetic effect for patients with keloidm
without increasing the adverse reactions.

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更新日期/Last Update: 2021-05-11