[1]吴一文. 大黄?虫丸联合氨甲环酸与谷胱甘肽治疗黄褐斑[J].中国美容医学,2019,(09):21-23.
　WU Yi-wen. Chinese Rhubarb Zhechong Pill Combined with Carbamy Lcyclic Acid andGlutathion in the Treatment of Chloasma[J].Medical Aesthetics and Beauty,2019,(09):21-23.
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 大黄?虫丸联合氨甲环酸与谷胱甘肽治疗黄褐斑
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《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2019年09期
页码:
21-23
栏目:
出版日期:
2019-09-05

文章信息/Info

Title:
 Chinese Rhubarb Zhechong Pill Combined with Carbamy Lcyclic Acid and
Glutathion in the Treatment of Chloasma
文章编号:
1008-6455（2019）09-0021-03
作者:
吴一文
Author(s):
WU Yi-wen
关键词:
 ; [关键词]大黄?虫丸; 氨甲环酸; 谷胱甘肽; 黄褐斑; 中西结合治疗
Keywords:
Key words: Chinese rhubarb Zhechong Pill;  tranexamic acid;  glutathione;  chloasma;  integrated treatment of Chinese andWestern medicine
分类号:
R758.4+2
文献标志码:
A
摘要:
[摘要]目的：探讨大黄?虫丸联合氨甲环酸与谷胱甘肽治疗黄褐斑的临床效果。方法：选取2017年1月-2018年1月来院治疗
的黄褐斑患者268例，按数字随机法，随机分成对照组与实验组，每组134例。其中对照组患者采用氨甲环酸，谷胱甘肽与维
生素C治疗黄褐斑，实验组患者则采用氨甲环酸，谷胱甘肽联合大黄?虫丸中西结合治疗黄褐斑，对两组患者的临床效果进
行对比分析。结果：对照组治疗总有效率为79.85%，实验组为93.28%，组间差异均有统计学意义（P ＜0.05）。对照组不良
反应中除去3例恶心者，1例头晕者外，其余患者均恢复良好，不良反应率为2.99%，实验组患者中仅有1例患者产生恶心等胃
肠道反应，不良反应率为0.75%，组间差异均有统计学意义（P ＜0.05）。结论：大黄?虫丸联合氨甲环酸与谷胱甘肽治疗黄
褐斑临床效果显著，不良反应率低，治疗方案更加安全，值得临床应用。

Abstract:
Abstract: Objective To investigate the clinical effect of Chinese rhubarb Zhechong Pill combined with tranexamic acid and
glutathione in the treatment of chloasma. Methods 268 patients with chloasma who came to our hospital from January 2017
to January 2018 were randomly divided into control group and experimental group. Each group had 30 cases. The control
group had 134cases treated with tranexamic acid, glutathione and vitamin C. The experimental group had 134 cases treated
with tranexamic acid, glutathione and Chinese rhubarb zhechong pill. The clinical effects of the two groups were analyzed and
compared. Results The total clinical effect of the control group was 79.85%, and that of the experimental group was 93.28%.
There were significant differences between the two groups (P ＜0.05). The adverse reactions in the control group were good
except for 3 nausea and 1 dizziness, and the rate of adverse reactions was 2.99%. Only one patient in the experimental group
had nausea and other gastrointestinal reactions, and the rate of adverse reactions was 0.75%. There were significant differences
between the two groups (P ＜0.05). Conclusion Chinese rhubarb zhechong Pill combined with tranexamic acid and glutathione
has significant clinical effect in the treatment of chloasma, with low adverse reactions and safer treatment plan, which is worthy
of clinical application.

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更新日期/Last Update: 2019-09-24