[1] 刘菲菲,周丽娟,李大鹏. 黄金微针射频联合重组牛碱性成纤维细胞生长因子凝胶治疗面部痤疮瘢痕临床研究[J].中国美容医学,2021,(1):57-60.
　 LIU Fei-fei,ZHOU Li-juan,LI Da-peng. A Clinical Study of Gold Microneedle Radiofrequency Combined RecombinantBovine-Basic Fibroblast Growth Factor Gel in the Treatment of Facial Acne Scar[J].Medical Aesthetics and Beauty,2021,(1):57-60.
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 黄金微针射频联合重组牛碱性成纤维细胞生长因子凝胶治疗面部痤疮瘢痕
临床研究

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《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2021年1期
页码:
57-60
栏目:
出版日期:
2021-01-10

文章信息/Info

Title:
 A Clinical Study of Gold Microneedle Radiofrequency Combined Recombinant
Bovine-Basic Fibroblast Growth Factor Gel in the Treatment of Facial Acne Scar
文章编号:
1008-6455（2021）01-0057-04
作者:
 刘菲菲; 周丽娟; 李大鹏
Author(s):
 LIU Fei-fei;  ZHOU Li-juan;  LI Da-peng
关键词:
 [关键词]黄金微针射频; rb-bFGF凝胶; 痤疮; 瘢痕; 皮肤屏障; ECCA评分
Keywords:
 Key words: gold microneedle radiofrequency;  Rb-bFGF gel;  acne scarring;  skin barrier;  ECCA score
分类号:
R619+.6
文献标志码:
A
摘要:
[摘要]目的：探讨黄金微针射频联合重组牛碱性成纤维细胞生长因子（rb-bFGF）凝胶治疗面部痤疮瘢痕的临床疗效。方
法：前瞻性选择2017年1月-2019年1月笔者医院诊治的92例面部痤疮瘢痕患者，按照入组奇、偶顺序将患者随机分为两组。
对照组：46例，采用黄金微针射频治疗；观察组：46例，采用黄金微针射频联合rb-bFGF凝胶治疗。比较两组疗效、结痂时
间、红斑持续时间、痤疮瘢痕评估量表（ECCA）权重评分、瘢痕基底深度、皮肤屏障功能和不良反应差异。结果：观察组治
疗总有效率高于对照组（P ＜0.05），结痂时间、红斑持续时间均短于对照组（P ＜0.05）。两组治疗后ECCA权重评分、瘢痕
基底深度、经皮水分丢失量、pH值低于治疗前（P ＜0.05），皮肤含水量高于治疗前（P ＜0.05）。观察组治疗后ECCA权重评
分、瘢痕基底深度、经皮水分丢失量、pH值低于对照组（P ＜0.05），皮肤含水量高于对照组（P ＜0.05）。观察组治疗期间
不良反应发生率低于对照组（P ＜0.05）。结论：黄金微针射频联合rb-bFGF凝胶治疗可改善面部痤疮瘢痕症状，减轻瘢痕基
底深度，增加皮肤屏障功能，提高治疗效果，降低不良反应。

Abstract:
Abstract: Objective To investigate the clinical effect of gold microneedle radiofrequency combined with recombinant bovinebasic
fibroblast growth factor (rb-bFGF) gel in the treatment of facial acne scar. Methods 92 patients with facial acne scar
diagnosed and treated in our hospital from January 2017 to January 2019 were prospectively selected and randomly divided into
two groups according to the odd and even order of enrollment. The control group (46 cases) was treated with gold microneedle
radiofrequency, and the observation group (46 cases) was treated with gold microneedle radiofrequency combined with rbbFGF
gel. The efficacy, scab time, erythema duration, acne scar assessment scale (ECCA) weight score, scar base depth, skin
barrier function and adverse reactions were compared between the two groups. Results The total effective rate of treatment
in the observation group was higher than that in the control group (P ＜0.05), and the scab time and erythema duration were
shorter than that in the control group (P ＜0.05). After treatment, ECCA weight score, scar base depth, transdermal water loss
and PH value of the two groups were lower than before treatment (P ＜0.05), and the skin moisture content was higher than
before treatment (P ＜0.05). After treatment, the weight score of ECCA, scar base depth, transdermal water loss, pH value of
the observation group were lower than those of the control group (P ＜0.05), and skin moisture content was higher than that
of the control group (P ＜0.05). The incidence of adverse reactions in the observation group was lower than that in the control
group (P ＜0.05). Conclusion Gold microneedle radiofrequency combined rb-bFGF gel treatment can improve facial acne scar
symptoms, reduce scar base depth, increase skin barrier function, improve treatment effect and reduce adverse reactions.

相似文献/References:

[1] 李凤英,熊坚癸,冯程程. 黄金微针射频联合透明质酸在面部皮肤年轻化中的应用效果研究[J].中国美容医学,2020,(9):38.
　 LI Feng-ying,XIONG Jian-gui,FENG Cheng-cheng. Study on the Application Effect of Gold Microneedle Radiofrequency Combinedwith Hyaluronic Acid in Facial Skin Rejuvenation[J].Medical Aesthetics and Beauty,2020,(1):38.
[2]祁 薇,李牧桑,朱忠义. 黄金微针射频联合rb-bFGF行面部年轻化的皮肤镜观察[J].中国美容医学,2020,(11):73.
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[3] 丁 峰,程 昆,何 芨,等. 黄金微针射频联合透明质酸在面部皮肤年轻化中的应用效果和安全性研究[J].中国美容医学,2021,(1):46.
　 DING Feng,CHENG Kun,HE Ji,et al. Application Effect and Safety of Gold Microneedle Radio Frequency Combined withHyaluronic Acid in Facial Skin Rejuvenation[J].Medical Aesthetics and Beauty,2021,(1):46.

更新日期/Last Update: 2021-02-02