[1] 肖芳玲 综述,谭 军 审校. 增生性瘢痕的药物治疗进展[J].中国美容医学,2021,(4):181-184.
　 XIAO Fang-ling,TAN Jun. Advances in Drug Treatment For Hypertrophic Scar[J].Medical Aesthetics and Beauty,2021,(4):181-184.
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 增生性瘢痕的药物治疗进展
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《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2021年4期
页码:
181-184
栏目:
出版日期:
2021-04-10

文章信息/Info

Title:
 Advances in Drug Treatment For Hypertrophic Scar
文章编号:
1008-6455(2021)04-0181-03
作者:
 肖芳玲1; 2 综述; 谭 军2 审校
Author(s):
 XIAO Fang-ling1; 2 ;  TAN Jun2
关键词:
 [关键词]增生性瘢痕; 药物; 曲安奈德; 氟尿嘧啶; 平阳霉素
Keywords:
 Key words: hypertrophic scar; drug; triamcinolone acetonide 5-fluorouracil; pingyangmycin
分类号:
R619+.6
文献标志码:
A
摘要:
[摘要]增生性瘢痕的治疗一直以来都是整形外科的难点及重点，其治疗手段多种多样，因人而异。药物治疗一直都是其主要
治疗手段之一，皮质类固醇激素尤其是曲安奈德为临床上运用最多的治疗瘢痕的药物，但越来越多的文献报道曲安奈德存在
毛细血管扩张和色素沉着等副作用。人们开始寻找其他治疗瘢痕的药物,希望提高疗效和减少副作用，如：5-氟尿嘧啶、平
阳霉素、A型肉毒毒素、钙通道阻滞剂及细胞因子相关药物等，它们越来越受到临床关注并被运用于临床中。不同的药物其
治疗机制不同，使用方法也不尽相同，本文主要介绍近年来国内外常见的治疗增生性瘢痕的药物及其相关机制。

Abstract:
Abstract:The treatment for hypertrophic scar has always been a difficult and key point in plastic surgery, and its treatment methods
are varied and vary from person to person. Drug therapy has always been one of the main treatment methods, Corticosteroid
hormones, especially triamcinolone acetonide, are the most widely used drugs in the clinical treatment of scar. However, more and
more literatures have reported that triamcinolone acetonide has side effects such as telangiectasis and chromaticity. People begin
to search for other drugs to treat scar, hoping to improve the efficacy and reduce side effects.such as 5-fluorouracil, pingyangmycin,
botulinum toxin type A, calcium channel blockers,cytokine related drugs, etc.which have attracted more and more clinical attention
and be used in the clinic.Different drugs have different therapeutic mechanisms and use methods. This paper mainly introduces
the common treatment drugs and the related mechanisms of hypertrophic scar at home and abroad in recent years.

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更新日期/Last Update: 2021-05-14