[1]宋 双,王 娜,吕继忠,等.不同比例CGF联合骨代用品对牙齿缺失后牙槽骨位点保存的对比研究[J].中国美容医学,2022,(8):151-155.
　SONG Shuang,WANG Na,LYU Jizhong,et al.Comparative Study on the Preservation of Alveolar Bone Sites after Tooth Loss with Different Proportions of CGF Combined with Bone Substitutes[J].Medical Aesthetics and Beauty,2022,(8):151-155.
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不同比例CGF联合骨代用品对牙齿缺失后牙槽骨位点保存的对比研究()
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《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2022年8期
页码:
151-155
栏目:
出版日期:
2022-08-10

文章信息/Info

Title:
Comparative Study on the Preservation of Alveolar Bone Sites after Tooth Loss with Different Proportions of CGF Combined with Bone Substitutes
文章编号:
1008-6455(2022)08-0151-04
作者:
宋 双; 王 娜; 吕继忠; 蒋江涛
(菏泽医学专科学校附属医院口腔科 山东 菏泽 274200 )
Author(s):
SONG Shuang;  WANG Na;  LYU Jizhong;  JIANG Jiangtao
(Department of Stomatology,Heze Medical College, Heze 274200, Shandong, China)
关键词:
浓缩生长因子; 位点保存; 牙槽骨; 牙槽嵴宽度; 角化龈宽度; 骨密度
分类号:
R783.1
文献标志码:
A
摘要:
目的：探讨不同比例CGF联合骨代用品对牙齿缺失后牙槽骨位点保存的对比研究。方法：选取2020年1月-2021年1月在菏泽医专附属医院口腔科接受患牙拔除后行拔牙位点保存的60例患者（60颗患牙）为研究对象，以随机数字表法分为三组，每组20例（20颗患牙），分别为试验1组（0.25g Bio-Oss骨粉+CGF膜1）、试验2组（0.25g Bio-Oss骨粉+CGF膜2）和试验3组（0.25g Bio-Oss骨粉+剪碎的CGF颗粒+CGF膜1）。患者于术后3、6个月复诊，所有患者均随访6个月，研究对比三组患者拔牙位点保存术前、术后3个月及6个月拔牙位点唇、腭侧骨板高度，牙槽嵴宽度、角化龈宽度和骨密度发生情况。结果：术前，三组的唇、腭侧骨板高度，牙槽嵴宽度、角化龈宽度和骨密度比较，差异均无统计学意义（P＞0.05）。与术前相比，术后3、6个月试验1组的唇、腭侧骨板高度均降低（P＜0.05）；与试验1组相比，试验3组术后6个月的唇、腭侧骨板高度均升高（P＜0.05）。术后3、6个月试验1组和试验2组两组患者的牙槽嵴宽度均小于术前（P＜0.05）；试验3组术后3、6个月的牙槽嵴宽度均高于试验1组（P＜0.05）。试验2组和试验3组两组患者术后3、6个月的角化龈宽度均高于术前（P＜0.05）；试验2组和试验3组两组患者术后3、6个月的角化龈宽度均高于试验1组（P＜0.05）。三组患者术后3个月的骨密度均高于术前，试验2组和试验3组患者术后6个月的骨密度均高于术前（P＜0.05）；试验2组和试验3组两组患者术后3、6个月的骨密度均高于试验1组（P＜0.05），差异均有统计学意义。结论：CGF联合骨代用品应用于患者牙齿拔除后拔牙位点的保存术中，0.25g Bio-oss骨粉+剪碎CGF颗粒1+CGF膜1比例混合时位点保存效果最佳，可有效维持唇、腭侧骨板高度，牙槽嵴宽度和骨密度，形成足量的角化龈组织，为种植修复提供有利条件。
Abstract:
Objective To explore the comparative study of different proportions of CGF combined with bone substitutes on?span style="font-family: tahoma, arial, helvetica, sans-serif;">alveolar bone site preservation after tooth loss. Methods A From January 2020 to January 2021, 60 patients (60 affected teeth)?span style="font-family: tahoma, arial, helvetica, sans-serif;">who received tooth extraction in the Department of Stomatology, Heze Medical College Affiliated Hospital were selected as?span style="font-family: tahoma, arial, helvetica, sans-serif;">the research objects. They were divided into 3 groups by random number table method, 20 cases (20 teeth) in each group:?span style="font-family: tahoma, arial, helvetica, sans-serif;">experimental 1 group (0.25g Bio-Oss bone meal+CGF membrane 1), test 2 group (0.25g Bio-Oss bone meal+CGF membrane?span style="font-family: tahoma, arial, helvetica, sans-serif;">2) and test 3 group (0.25g Bio-Oss bone meal+chopped CGF particles+CGF membrane 1). The patients were immediately?span style="font-family: tahoma, arial, helvetica, sans-serif;">followed up at 3 and 6 months after surgery, and all were followed up for 6 months. The study compared the three groups of?span style="font-family: tahoma, arial, helvetica, sans-serif;">patients with the extraction site preservation before surgery, 3 and 6 months after the extraction site, the height of the lip, palatal?span style="font-family: tahoma, arial, helvetica, sans-serif;">bone plate, and the tooth extraction site. The occurrence of groove ridge width, keratinized gingiva width and bone mineral?span style="font-family: tahoma, arial, helvetica, sans-serif;">density. Results Before surgery, there was no significant difference in the height of the lip and palatal bone plate, the width of?span style="font-family: tahoma, arial, helvetica, sans-serif;">the alveolar ridge, the width of the keratinized gingiva and the bone mineral density among the three groups (P?span style="font-family: 宋体;">＞0.05). Compared with preoperative, the heights of labial and palatal bone plates in experimental 1 group?span style="font-family: tahoma, arial, helvetica, sans-serif;">decreased at 3 and 6 months after operation (P＜0.05). The height of the palatal bone plate increased (P＜0.05).?span style="font-family: tahoma, arial, helvetica, sans-serif;">At 3 and 6 months after operation, the alveolar ridge width of patients in experimental 1 group and experimental 2?span style="font-family: tahoma, arial, helvetica, sans-serif;">group was smaller than that before operation (P＜0.05); the alveolar ridge width of experimental 3 group was higher than that of?span style="font-family: tahoma, arial, helvetica, sans-serif;">experimental 1 at 3 group and 6 months after operation (P＜0.05). The keratinized gingival widths of patients in experimental 2 group and experimental 3 group were higher than those before operation at 3 and 6 months after operation (P＜0.05). The width?span style="font-family: tahoma, arial, helvetica, sans-serif;">of the keratinized gingiva was higher than that of the experimental 1 group (P＜0.05). The bone mineral density of the three?span style="font-family: tahoma, arial, helvetica, sans-serif;">groups of patients at 3 months after operation was higher than that before operation, and the bone mineral density of patients?span style="font-family: tahoma, arial, helvetica, sans-serif;">in experimental 2 group and experimental 3 group at 6 months after operation was higher than that before operation (P＜0.05).?span style="font-family: tahoma, arial, helvetica, sans-serif;">The bone mineral density of patients in experimental group 3 and 6 months after operation was higher than that in experimental?span style="font-family: tahoma, arial, helvetica, sans-serif;">1 group (P＜0.05). Conclusion CGF combined with bone substitutes is used in the preservation of tooth extraction sites?span style="font-family: tahoma, arial, helvetica, sans-serif;">after tooth extraction. The site preservation effect is the best when 0.25g Bio-Oss bone powder is mixed with chopped CGF?span style="font-family: tahoma, arial, helvetica, sans-serif;">particles 1+CGF membrane 1 in the ratio, which can effectively maintain the lip, the height of the palatal bone plate, the width?span style="font-family: tahoma, arial, helvetica, sans-serif;">of the alveolar ridge and the bone mineral density can form a sufficient amount of keratinized gingival tissue, which provides?span style="font-family: tahoma, arial, helvetica, sans-serif;">favorable conditions for implant restoration

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更新日期/Last Update: 2022-08-29