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《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:

期数:

2023年9期

页码:

152-155

栏目:

出版日期:

2023-09-10

文章信息/Info

Title:

Effects of Tinidazole Assisted Root Canal Filling on Periodontal Microecology and Red-White Aesthetics in Patients with Endodontic Diseases

文章编号:

1008-6455（2023）09-0152-03 Effects of Ti

作者:

王维维¹ ; 刘 捷² ; 陈云剑³

(1.明光市人民医院口腔科 安徽 滁州 239400 2.滁州市中西医结合医院口腔科 安徽 滁州 239000 3.黄山市屯溪区云剑口 腔门诊部 安徽 黄山 245000 )

Author(s):

WANG Weiwei¹ ; LIU Jie² ; CHEN Yunjian³

( 1.Department of Stomatology,Mingguang Peoples Hospital,Chuzhou 239400,Anhui,China 2.Department of Stomatology,Chinese and Western Medicine Combined Hospital of Chuzhou,Chuzhou 239000,Anhui,China 3.Yunjian Dental Clinic of Tunxi District,Huangshan 245000,Anhui,China)

关键词:

牙体牙髓病; 根管充填; 替硝唑; 牙周微生态; 龈沟液; 炎症因子; 红白美学

Keywords:

endodontic diseases root canal fi lling tinidazole periodontal microecology gingival crevicular fl uid infl ammatory factors red-white aesthetics

分类号:

R781.33

文献标志码:

A

摘要:

目的：探讨替硝唑辅助根管充填对牙体牙髓病患者牙周微生态、龈沟液炎症因子及红白美学的影响。方法：按照随 机数字表法将2019年6月-2021年8月笔者医院收治的80例牙体牙髓病患者分为对照组和观察组，每组40例。对照组采用次氯 酸钠消毒联合环氧树脂类糊剂根管充填，观察组采用替硝唑辅助环氧树脂类糊剂根管充填。比较两组的牙周微生态指标[菌 斑指数（Plaque index，PLI）、龈沟出血指数（Sulcus bleeding index，SBI）、牙龈指数（Gingival index，GI）和牙周 袋深度（Periodontal deep，PD）]、龈沟液炎症因子[白细胞介素-1β（Interleukin-1β，IL-1β）、IL-4和超敏C反应蛋白 （High-sensitivity C-reactive protein，hs-CRP）]水平及红白美学指标。结果：治疗1个月后，观察组的PLI、SBI、GI、PD 及龈沟液IL-1β、IL-4、hs-CRP水平明显低于对照组(P＜0.05)；观察组的PES评分、WES评分明显高于对照组(P＜0.05)。结 论：替硝唑辅助根管充填能有效调节牙体牙髓病患者的牙周微生态情况，抑制炎症反应，改善红白美学效果。

Abstract:

Objective To investigate the effects of tinidazole assisted root canal filling on periodontal microecology, inflammatory factors of gingival crevicular fluid and red-white aesthetics in patients with endodontic diseases. Methods According to the random number table method, 80 patients with endodontic diseases who were divided into control group and observation group in the authors hospital from June 2019 to August 2021, 40 cases in each group. The control group was given sodium hypochlorite disinfection combined with epoxy resin paste root canal filling, and the observation group was given tinidazole assisted root canal fi lling with epoxy resin paste. The periodontal microecological indexes[plaque index(PLI), sulcus bleeding index(SBI), gingival index(GI) and periodontal pocket depth(PD)], levels of gingival crevicular fl uid infl ammatory factors[INTERleukin-1β(IL-1β), IL-4 and hypersensitive C-reactive protein (HS-CRP)] and red-white aesthetic indexes (PES, WES) were compared between the two groups. Results 1 month after treatment, the PLI, SBI, GI, PD and levels of gingival crevicular fl uid IL-1, IL-4, hs-CRP in observation group was signifi cantly lower than that in control group(P ＜0.05). The PES score and the WES score in observation group were significantly higher than that in control group(P＜0.05). Conclusion Tinidazole assisted root canal filling could effectively regulate the periodontal microecology of patients with endodontic diseases, inhibit the infl ammatory response and improve the red-white aesthetic eff ect.

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更新日期/Last Update: 2023-10-16