[1] 熊斯颖,杨 艳,邵 蕾,等. 浅表切削联合光动力疗法治疗面部鳞状细胞癌的疗效与安全性探析[J].中国美容医学,2020,(8):59-61.
　 XIONG Si-ying,YANG Yan,SHAO Lei,et al. Clinical Effect and Safety of Superfi cial Resection Combined with PhotodynamicTherapy for Facial Squamous Cell Carcinoma[J].Medical Aesthetics and Beauty,2020,(8):59-61.
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 浅表切削联合光动力疗法治疗面部鳞状细胞癌的疗效与安全性探析
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《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2020年8期
页码:
59-61
栏目:
出版日期:
2020-08-10

文章信息/Info

Title:
 Clinical Effect and Safety of Superfi cial Resection Combined with Photodynamic
Therapy for Facial Squamous Cell Carcinoma
文章编号:
1008-6455（2020）08-0059-03
作者:
 熊斯颖; 杨 艳; 邵 蕾; 田 歆; 刘玉梅
Author(s):
 XIONG Si-ying; YANG Yan; SHAO Lei; TIAN Xin; LIU Yu-mei
关键词:
 [关键词]浅表切除; 5-氨基酮戊酸光动力疗法; 面部鳞状细胞癌; 临床效果; 安全性
Keywords:
 Key words:superficial resection; photodynamic therapy with 5-aminoketovalerate;  facial squamous cell carcinoma;  clinicaleffect;  security
分类号:
R739.5
文献标志码:
A
摘要:
[摘要]目的：探讨浅表切除联合光动力疗法治疗面部鳞状细胞癌的临床效果与安全性。方法：本研究回顾性分析2015年1
月-2018年1月笔者科室接受治疗的面部鳞状细胞癌患者40例病例资料，根据患者接受治疗方式的不同分为研究组（n =20）和
对照组（n=20），分别接受浅表切除联合光动力疗法和单纯浅表切除治疗。比较了两组患者的整体切除率、完全切除率和治
愈性切除率，手术相关的并发症发生率以及累积复发率等。结果：治疗前，两组患者的年龄、性别、既往史、体重指数、肿
瘤特征（数目、位置、形状、最大直径、周长以及深度）均无明显差异（均P ＞0.05）。两组患者的整体切除率（93.5% vs
93.8%，P =1.000）、完全切除率（69.6% vs 76.2%，P =0.433）以及治愈性切除率（54.3% vs 60.0%，P =0.602）均无明显差
异。治疗组的累积复发率明显低于对照组（0.0% vs 5.1%，P =0.007）。结论：浅表切除联合光动力疗法对于面部鳞状细胞
癌的临床效果好，安全性高，值得在临床上推广应用。

Abstract:
Abstract:Objective This study aims to investigate the clinical efficacy and safety of superficial resection combined with
photodynamic therapy for facial squamous cell carcinoma. Methods This study retrospectively analyzed 40 patients with
facial squamous cell carcinoma who received treatment in our department of dermatology from January 2015 to January 2018.
According to different treatment methods, the patients were divided into study group (n =20) and control group (n =20), who
received superfi cial resection combined with photodynamic therapy and simple superfi cial resection respectively. The overall
resection rate, complete resection rate and curative resection rate, the incidence of surgically related complications, and the
cumulative recurrence rate were compared between the two groups. Results There was no signifi cant difference in age, sex,
past history, body mass index, tumor characteristics (number, location, shape, maximum diameter, circumference and depth)
between the two groups (all P ＞0.05). There was no significant difference in the overall resection rate (93.5% vs. 93.8%,
P =1.000), complete resection rate (69.6% vs.76.2%, P =0.433), or curative resection rate (54.3% vs. 60.0%, P =0.602). The
cumulative recurrence rate was signifi cantly lower in the treatment group than in the control group (0.0% vs.5.1%,P =0.007).
Conclusion Superfi cial excision combined with photodynamic therapy for facial squamous cell carcinoma has a good clinical
effect and high safety.

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更新日期/Last Update: 2020-08-26