[1] 钟淑贤,李 春,李 瑜,等. 富血小板血浆治疗雄激素性脱发的Meta分析[J].中国美容医学,2021,(9):36-40.
　 ZHONG Shu-xian,LI Chun,LI Yu,et al. Meta-analysis of Platelet-rich Plasma in the Treatment of Androgenetic Alopecia[J].Medical Aesthetics and Beauty,2021,(9):36-40.
点击复制

 富血小板血浆治疗雄激素性脱发的Meta分析
()
分享到：

《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2021年9期
页码:
36-40
栏目:
出版日期:
2021-09-10

文章信息/Info

Title:
 Meta-analysis of Platelet-rich Plasma in the Treatment of Androgenetic Alopecia
文章编号:
1008-6455（2021）09-0036-05
作者:
 钟淑贤1; 李 春2; 李 瑜2; 方素娟3
Author(s):
 ZHONG Shu-xian1; LI Chun2; LI Yu2; FANG Su-juan3
关键词:
 [关键词]富血小板血浆; 雄激素性脱发; 脂溢性脱发; Meta分析; 毛发计数; 毛发密度
Keywords:
 Key words: platelet-rich plasma;  androgenetic alopecia;  seborrheic alopecia;  Meta-analysis;  hair count;  hair density
分类号:
R622
文献标志码:
A
摘要:
[摘要]目的：系统评价富血小板血浆治疗雄激素性脱发的有效性，为临床治疗提供参考依据。方法：应用计算机全面检索国
内外数据库，纳入符合标准的富血小板血浆治疗雄激素性脱发的随机对照试验，进行文献的筛选、信息提取和质量评价后，
进行Meta分析。结果：最终纳入12篇文献，共759例患者。经Meta分析，富血小板血浆治疗雄激素性脱发患者的毛发计数、
毛发厚度高于多脱氧核糖核苷酸、或安慰剂、或安慰剂联合治疗，毛发密度、终毛密度高于安慰剂、或安慰剂联合治疗，临
床疗效优于米诺地尔、或毛发移植、或安慰剂联合治疗，差异均具有统计学意义（P ＜0.05）。结论：富血小板血浆能增加
毛发数量、毛发密度、毛发厚度和终毛密度，逆转雄激素性脱发患者毛囊逐渐微型化的进程，从而改善患者脱发情况，具有
良好的临床疗效。

Abstract:
Abstract: Objective The effectiveness of platelet-rich plasma in the treatment of androgenetic alopecia was systematically
evaluated to provide a basis for clinical treatment. Methods Computers were used to comprehensively search the domestic and
foreign databases. Randomized controlled trials of platelet-rich plasma in the treatment of androgenetic alopecia were included.
After literature screening, information extraction and quality evaluation, Meta-analysis was performed. Results Finally, 12
articles were included, with a total of 759 patients. According to Meta-analysis, the hair count and hair thickness of patients
with androgenetic alopecia treated with platelet-rich plasma were higher than that treated with polydeoxyribonucleotides, or
placebo, or placebo combination therapy. Hair density and terminal hair density were higher than that treated with placebo,
or placebo combination therapy. The clinical effects were better than that treated with minoxidil, or hair transplantation,
or placebo combination therapy. The differences were statistically significant (P ＜0.05). Conclusion Platelet-rich
plasma can increase the number of hairs, hair density, hair thickness and terminal hair density, and reverse the process of
miniaturization of hair follicles in patients with androgenetic alopecia. Platelet-rich plasma improves hair loss in patients and
has good clinical effects.

相似文献/References:

[1] 刘小飞,汤育森. PRP注射联合自体脂肪移植的效果及对脂肪成活率的影响研究[J].中国美容医学,2020,(7):67.
　 LIU Xiao-fei,TANG Yu-sen. Effect of PRP Injection Combined with Autologous Fat Transplantation and its Effecton Fat Survival Rate[J].Medical Aesthetics and Beauty,2020,(9):67.
[2] 阎昱丞,王羽晨,杨明勇. PRP结合自体脂肪移植在面部年轻化中的应用[J].中国美容医学,2020,(11):47.
　 YAN Yu-cheng,WANG Yu-chen,YANG Ming-yong. Application of Platelet-rich Plasma(PRP) Combined with Autologous FatTransplantation in Facial Rejuvenation[J].Medical Aesthetics and Beauty,2020,(9):47.
[3] 杨晓双 综述,吕中法 审校. 浓缩生长因子在雄激素性脱发中的治疗进展[J].中国美容医学,2021,(2):179.
　 YANG Xiao-shuang,LV Zhong-fa. Application of Concentrated Growth Factors in Treatment of Androgenetic Alopecia[J].Medical Aesthetics and Beauty,2021,(9):179.
[4] 杨丽英,罗 鹏,陈 玲. 富血小板血浆对难治性皮肤溃疡创面愈合及肉芽组织中TGF-1及EGF表达的影响[J].中国美容医学,2021,(5):48.
　[J].Medical Aesthetics and Beauty,2021,(9):48.
[5] 周亚光,于 水,赵纪敏,等. A型肉毒毒素治疗雄激素性脱发的临床研究[J].中国美容医学,2021,(5):101.
　 ZHOU Ya-guang,YU Shui,ZHAO Ji-min,et al. A Clinical Study on the Treatment of Androgenic Alopecia with Botulinum Toxin A[J].Medical Aesthetics and Beauty,2021,(9):101.
[6]刘 阳,曲 茜,樊哲祥,等. 低能量激光治疗女性型脱发的随机对照临床研究[J].中国美容医学,2021,(10):73.
　 LIU Yang,QU Qian,FAN Zhe-xiang,et al. Low-level Laser Therapy for Female Pattern Hair Loss: A Randomized ControlledClinical Study[J].Medical Aesthetics and Beauty,2021,(9):73.
[7]王 薇,曹 卉,肖敬川,等.富血小板血浆联合米诺地尔酊治疗雄激素性脱发疗效观察[J].中国美容医学,2023,(3):95.
　WANG Wei,CAO Hui,XIAO Jingchuan,et al.Clinical Effect of Platelet-rich Plasma Combined with Minoxidil Tincture on Androgenetic Alopecia[J].Medical Aesthetics and Beauty,2023,(9):95.
[8]汪晓丹,翁文佳,张 明,等.外用域发液体敷料联合微针治疗雄激素性脱发的疗效观察[J].中国美容医学,2023,(6):65.[doi:10.15909/j.cnki.cn61-1347/r.005748]
　WANG Xiaodan,WENG Wenjia,ZHANG Ming,et al.Comparative Study on the Effi cacy of Yufa Solution Combined with Microneedling in the Treatment of Androgenetic Alopecia[J].Medical Aesthetics and Beauty,2023,(9):65.[doi:10.15909/j.cnki.cn61-1347/r.005748]
[9]李 军,田力娣,赵 艳,等.点阵CO2激光联合米诺地尔治疗雄激素性脱发的疗效及安全性分析[J].中国美容医学,2024,(2):82.[doi:10.15909/j.cnki.cn61-1347/r.006151]
　LI Jun,TIAN Lidi,ZHAO Yan,et al.Efficacy and Safety of Fractional CO2 Laser Combined with Minoxidil in the Treatment of Androgenetic Alopecia[J].Medical Aesthetics and Beauty,2024,(9):82.[doi:10.15909/j.cnki.cn61-1347/r.006151]

更新日期/Last Update: 2021-10-09