[1] 赵文宇,化昊天,胡延申,等. 果酸治疗寻常痤疮疗效的 Meta 分析[J].中国美容医学,2021,(9):111-114.
　 ZHAO Wen-yu,HUA Hao-tian,HU Yan-shen,et al. The Effect of Safety of Alpha Hydroxy Acid in the Treatment of Acne Vulgaris:A MetaAnalysis[J].Medical Aesthetics and Beauty,2021,(9):111-114.
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 果酸治疗寻常痤疮疗效的 Meta 分析
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《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2021年9期
页码:
111-114
栏目:
出版日期:
2021-09-10

文章信息/Info

Title:
 The Effect of Safety of Alpha Hydroxy Acid in the Treatment of Acne Vulgaris:A Meta
Analysis
文章编号:
1008-6455(2021)09-0111-04
作者:
 赵文宇1; 化昊天1; 胡延申1; 方玉甫2
Author(s):
 ZHAO Wen-yu1; HUA Hao-tian1; HU Yan-shen1; FANG Yu-fu2
关键词:
 [关键词]果酸; 阿达帕林凝胶; 寻常痤疮; 不良反应; 复发
Keywords:
 Key words: alpha hydroxy acid;  adapalene gel;  acne vulgaris;  adverse reactions;  recurrence
分类号:
R758.73+3
文献标志码:
A
摘要:
[摘要]目的：系统评价果酸治疗寻常痤疮的临床疗效及安全性。方法：计算机检索中国知网CNKI、万方数据资源系统
WANFANG DATE、中文科技期刊全文数据库VIP,Pubmed数据库；并手工检索纳入文献的参考文献，相关学位论文和会议论文
集。采纳符合标准的RCT，试验组采用果酸治疗，对照组采用阿达帕林凝胶外用治疗，并用RevMan 5.3 软件对其进行统计学
分析。检索时间为：2002年2月7日-2020年2月7日。结果：共纳入文献9篇，868例寻常痤疮患者。果酸治疗寻常痤疮的总有
效率RR (95% CI )1.37[1.17,1.61]、不良反应发生率RR (95% CI )0.47[0.31,0.73]，复发率RR (95% CI )0.23[0.10,0.53]均优
于阿达帕林凝胶，差异均具有统计学意义（P ＜0.01）。结论：果酸在治疗寻常痤疮方面具有一定的优势，且其与阿达帕林
凝胶相比有较低的不良反应发生率和复发率。

Abstract:
Abstract: Objective To systematically evaluate the clinical efficacy and safety of fruit acids in the treatment of acne vulgaris.
Methods Computer searched CNKI, WANFANG DATE, VIP, Pubmed database and manually searched references included in
the literature, related dissertations and conference proceedings. The standard RCT was adopted, the test group was treated with
fruit acid, and the control group was treated with adapalene gel externally, and the RevMan 5.3 software was used for statistical
analysis. The retrieval time is February 7, 2002 to February 7, 2020. Results A total of 9 articles were included, including
868 acne patients. The total effective RR (95%CI ) of fruit acid in the treatment of acne was 1.37 [1.17,1.61], the incidence
of adverse reactions RR (95% CI ) 0.47 [0.31,0.73], and the recurrence rate RR (95% CI ) 0.23 [0.10,0.53 ] Are better than
adapalene gel, the difference is statistically significant (P ＜0.01). Conclusion Fruit acid has certain advantages in the treatment
of acne, and compared with adapalene gel, it has a lower incidence of adverse reactions and recurrence.

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更新日期/Last Update: 2021-10-11