[1]郭 欣,喻书琛,李美文,等.吲哚菁绿介导的光动力疗法对牙周炎疗效的Meta分析[J].中国美容医学,2022,(1):111-114.
　GUO Xin,YU Shushen,LI Meiwen,et al.The Effect of Indocyanine Green-mediated Photodynamic Therapy in Treating Periodontitis: A Meta-analysis[J].Medical Aesthetics and Beauty,2022,(1):111-114.
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吲哚菁绿介导的光动力疗法对牙周炎疗效的Meta分析()
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《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2022年1期
页码:
111-114
栏目:
出版日期:
2022-01-10

文章信息/Info

Title:
The Effect of Indocyanine Green-mediated Photodynamic Therapy in Treating Periodontitis: A Meta-analysis
文章编号:
1008-6455（2022）01-0111-04
作者:
郭 欣1; 2 ; 喻书琛1; 李美文1; 2; 李 昂1; 2
(1.西安交通大学口腔医院 陕西省颅颌面精准医学研究重点实验室 陕西 西安 710004 ;2.西安交通大学口腔医院牙周黏膜病科 陕西 西安 710004 )
Author(s):
GUO Xin1; 2;  YU Shushen1 ; LI Meiwen 1; 2 ; LI Ang 1; 2
(1.Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research,Hospital of Stomatology,Xian Jiaotong University,Xian 710004,Shaanxi,China; 2.Department of Periodontics & Oral Mucosal Diseases,Hospital of Stomatology of Xian Jiaotong University, Xian 710004,Shaanxi, China)
关键词:
吲哚菁绿; 光动力疗法; 慢性牙周炎; 非手术治疗; 洁治刮治; Meta分析
Keywords:
indocyanine green (ICG); photodynamic therapy (PDT); chronic periodontitis;  non-surgical treatment;  scaling and root planning;  Meta-analysis
分类号:
R781.4+2
文献标志码:
A [
摘要:
目的：评价吲哚菁绿（Indocyanine green,ICG）介导的光动力疗法（Photodynamic therapy, PDT）（ICG-PDT）在治疗慢性牙周炎中的疗效。方法：检索EMBASE、Cochrane Library、Medline/PubMed、中国期刊全文数据库（CNKI）和中国生物医学文献数据库（CBM），截止时间2020年7月28日。筛选研究ICG-PDT治疗慢性牙周炎的随机对照试验（RCT），实验组采用ICG-PDT疗法，对照组采用单纯SRP治疗。结果：共纳入8项RCT，312例受试者。治疗3个月后，ICG-PDT组的探诊深度（PPD）、菌斑指数（PI）、临床附着丧失（CAL）改善均显著优于对照组,差异有统计学意义（P＜0.05），但是在相对附着水平（RAL）、探诊出血（BOP）、牙龈退缩（GR）方面与对照组相比无明显差异（P＞0.2）；治疗6个月后，ICG-PDT组的PI、CAL改善情况均显著优于对照组,差异有统计学意义（P＜0.05）。结论：ICG-PDT辅助SRP治疗慢性牙周炎效果显著优于传统的SRP治疗。
Abstract:
Objective To evaluate the efficacy of indocyanine green (ICG) mediated photodynamic therapy (PDT) (ICG -PDT) in treating chronic periodontitis. Methods The EMBASE, Cochrane library, Medline/PubMed, CNKI, and CBM databases were searched up to 28th July 2020. Only randomized controlled trials (RCTs) were included. The test group received ICG -PDT combined with scaling and root planning (SRP), while the control group only received SRP. Results Eight RCTs involving 312 participants were included. The ICG -PDT group showed greater improvements referring probing pocket depth (PPD), plaque index (PI), clinical attachment loss (CAL) after 3 months than that of the control group (P ＜0.05). However, no significant differences between groups were observed for relative attachment level (RAL)、bleeding on probing (BOP) and gingival recession (GR) (P＞0.2).After 6mouths, ICG -PDT group showed greater improvements referring PI, CAL when compared with the control group (P＜0.05). Conclusion ICG mediated PDT provides additional benefits in treating chronic periodontitis than SRP alone

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更新日期/Last Update: 2022-02-10