[1]张孟丽,张二佳,黄玉清,等. 皮秒翠绿宝石激光点阵模式治疗黄褐斑疗效观察[J].中国美容医学,2019,(05):4-7.
　ZHANG Meng-li,ZHANG Er-jia,HUANG Yu-qing,et al. Efficacy of the Fractional Picosecond Alexandrite Laser in the Treatment of Melasma[J].Medical Aesthetics and Beauty,2019,(05):4-7.
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 皮秒翠绿宝石激光点阵模式治疗黄褐斑疗效观察
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《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2019年05期
页码:
4-7
栏目:
出版日期:
2019-05-10

文章信息/Info

Title:
 Efficacy of the Fractional Picosecond Alexandrite Laser in the Treatment of Melasma
文章编号:
1008-6455(2019)05-0004-04
作者:
 张孟丽; 张二佳; 黄玉清; 林 彤
Author(s):
 ZHANG Meng-li; ZHANG Er-jia; HUANG Yu-qing; LIN Tong
关键词:
 ; [关键词]黄褐斑; 皮秒; 翠绿宝石激光; 点阵激光; 衍射微透镜阵列技术
Keywords:
 ; Key words: melasma;  picosecond;  alexandrite laser;  fractional laser; diffractive Lens array
分类号:
R758.4+2
文献标志码:
A
摘要:

[摘要]目的：观察皮秒翠绿宝石激光点阵模式治疗黄褐斑的疗效及安全性。方法：分析在笔者科室进行皮秒翠绿宝石激光点
阵模式治疗并随访3次以上的23例黄褐斑患者资料，利用黄褐斑面积及严重程度评分（Melasma Area and Severity Index，
MASI）和医生整体评价法（Physician Global Assessment，PGA）对疗效进行评估，并记录不良反应。结果：23例黄褐斑
患者经过3次治疗后，平均MASI评分较治疗前下降3.38±4.37，差异有统计学意义（P =0.001）。其中15例采用光斑6mm，
能量密度0.71J/cm2治疗，8例采用光斑8mm，能量密度0.4J/cm2治疗，两组MASI评分较治疗前均有统计学意义（P =0.009，
P =0.034），但两组比较，差异无统计学意义（P =0.452）。此外, 根据PGA评分，3次治疗后黄褐斑为轻度改善。不良反应主
要表现为轻微的红斑。结论：皮秒翠绿宝石激光点阵模式治疗黄褐斑安全、有效。

Abstract:
Abstract: Objective To investigate the efficacy and adverse reactions of the fractional picosecond Alexandrite laser in
melasma treatment. Methods The patients with melasma treated with the fractional mode of picosecond Alexandrite laser
in our department and followed up for more than three times were retrospectively analyzed. The efficacy was evaluated by
the Melasma Area and Severity Index (MASI) and the Physician Global Assessment (PGA). Related adverse reactions were
documented in detail. Results A total of 23 patients with melasma were analyszed in our study. After 3 treatments, the MASI
score decreased by 3.38±4.37, and the difference was statistically significant (P =0.001). Among them, 15 were treated with a
6-mm spot size and energy density of 0.71 J /cm2, 8 were treated with an 8-mm spot size and energy density of 0.4 J /cm2. The
changes of their MASI score in each group were statistically significant (P =0.009 and P =0.034 respectively), but the differences
between the both groups were not statistically significant (P =0.452). Besides, according to the PGA score, the melasma was
slightly improved with 3 treatments of picosecond Alexandrite laser. Adverse reactions were mainly characterized by mild
erythema. Conclusion The fractional picosecond Alexandrite laser with a diffractive lens array is safe and effective in the
treatment of melasma.

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更新日期/Last Update: 2019-06-03