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《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:

期数:

2021年4期

页码:

66-70

栏目:

出版日期:

2021-04-10

文章信息/Info

Title:

 Application Effect of Low-dose Dexmedetomidine Combined with Propofol and
Sufentanil in Facial Plastic Surgery

文章编号:

1008-6455（2021）04-0066-04

作者:

 马 茜; 白 雪; 王倩钰; 邓晓明

Author(s):

 MA Qian; BAI Xue; WANG Qian-yu; DENG Xiao-ming

关键词:

 [关键词]右美托咪定; 丙泊酚; 舒芬太尼; 面部整形手术; 麻醉; 血流动力学

Keywords:

 Key words: dexmedetomidine;  propofol;  sufentanil;  facial plastic surgery;  anesthesia;  hemodynamics

分类号:

R622

文献标志码:

A

摘要:

[摘要]目的：探究低剂量右美托咪定复合丙泊酚联合舒芬太尼用于面部整形手术的临床效果。方法：前瞻性选择2018年8
月-2019年10月在中国医学科学院北京协和医学院整形外科医院就诊后接受面部整形手术的患者60例。将全部患者根据随
机数字表法分为对照组以及观察组，每组30例。对照组使用丙泊酚联合舒芬太尼进行麻醉，观察组使用右美托咪定+丙泊
酚联合舒芬太尼进行麻醉。对比两组血流动力学指标[麻醉诱导前，麻醉后15min，手术开始，手术完成时的平均动脉压
（MAP）、心率（HR）、动脉血氧分压（SpO2）]，术后苏醒时间，术后清醒时间，视觉模拟评分（Visual analog scale，
VAS），镇静评分（Ramsay评分），术中体动次数和舒芬太尼追加使用剂量，麻醉恢复室内不良反应发生率以及手术医生、
麻醉医生、患者的满意度。结果：两组麻醉诱导前、麻醉后15min、手术开始、手术完成时的MAP、HR、SpO2比较差异均不
具有统计学意义（P ＞0.05）。观察组的术后苏醒时间、术后清醒时间均短于对照组，差异有统计学意义（P ＜0.05）。
观察组术后的VAS评分、镇静评分高于对照组，差异有统计学意义（P ＜0.05）。观察组术中体动次数和舒芬太尼追加使
用剂量均低于对照组，差异有统计学意义（P ＜0.05）。两组在麻醉恢复室内不良反应发生率比较差异不具有统计学意义
（P ＞0.05）。且两组手术医生、麻醉医生、患者满意度比较差异不具有统计学意义（P ＞0.05）。结论：接受面部整形手
术的患者，采用低剂量右美托咪定复合丙泊酚的麻醉方法，可保证手术过程中血流动力学的稳定，并有助于缩短术后清醒时
间，改善术后的镇静效果，并且安全性良好。

Abstract:

Abstract: Objective To explore the clinical effect of low-dose dexmedetomidine combined with propofol and sufentanil in
facial plastic surgery. Methods Prospective selection of 60 patients who underwent facial plastic surgery in the Plastic Surgery
Hospital of Chinese Academy of Medical Sciences and Peking Union Medical College from August 2018 to October 2019.
According to the method of random number table, all patients were divided into the control group and the observation group
with the same number of people. The number of patients in each group was 30 cases. The control group was anesthetized
with propofol combined with sufentanil, and the observation group was anesthetized with dexmedetomidine +propofol
combined with sufentanil. Compared the hemodynamic indexes of the two groups [before induction of anesthesia, 15min after
anesthesia, start of the operation, mean arterial pressure (MAP), heart rate (HR), arterial partial pressure of oxygen (SpO2) at the
completion of the operation], and wake up after operation time, postoperative awake time, visual analog scale (VAS), sedation
score (Ramsay score), intraoperative body movements, additional doses of sufentanil, adverse reactions in the anesthesia
recovery room, surgeon satisfaction, anesthesia doctor’s satisfaction, patient’s satisfaction. Results There were no statistically
significant differences in the MAP, HR, and SpO2 of the two groups of patients before induction of anesthesia, 15 minutes after
anesthesia, the beginning of the operation, and the completion of the operation (P ＞0.05). The postoperative wake-up time and
postoperative awake time of the observation group were shorter than those of the control group, the differences were statistically
significant (P ＜0.05). The postoperative VAS score and the sedation score were higher than those of the control group (P ＜0.05).
The number of body movements and the additional dose of sufentanil in the observation group were lower than those in the
control group (P ＜0.05). The difference in the incidence of adverse reactions in the anesthesia recovery room between the two
groups was not statistically significant (P ＞0.05). There was no statistically significant difference in satisfaction data between
the two groups of surgeons, anesthesiologists, and patient’s (P ＞0.05). Conclusion For patients undergoing facial plastic
surgery, the use of low-dose dexmedetomidine combined with propofol anesthesia can ensure the stability of hemodynamics
during the operation, and help to shorten the postoperative wakefulness time and improve postoperative sedation Painful effect
and good safety.

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更新日期/Last Update: 2021-05-11