[1] 张 萌,胡中柱. 低能量Q开关Nd:YAG激光和点阵微针射频联合治疗黄褐斑的有效性和安全性研究[J].中国美容医学,2020,(7):32-35.
　 ZHANG Meng,HU Zhong-zhu. Study on the Effi cacy and Safety of Low Energy Q-switched Nd:YAG Laser Combinedwith Fractional Microneedle Radiofrequency in the Treatment of Chloasma[J].Medical Aesthetics and Beauty,2020,(7):32-35.
点击复制

 低能量Q开关Nd:YAG激光和点阵微针射频联合治疗黄褐斑的有效性和安全性研究
()
分享到：

《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2020年7期
页码:
32-35
栏目:
出版日期:
2020-07-10

文章信息/Info

Title:
 Study on the Effi cacy and Safety of Low Energy Q-switched Nd:YAG Laser Combined
with Fractional Microneedle Radiofrequency in the Treatment of Chloasma
文章编号:
1008-6455(2020)07-0032-04
作者:
 张 萌; 胡中柱
Author(s):
 ZHANG Meng; HU Zhong-zhu
关键词:
 [关键词]低能量Q开关; Nd:YAG激光; 点阵微针射频; 黄褐斑; 有效性; 安全性
Keywords:
 Key words:low energy Q switch;  Nd:YAG laser;  RF of dot matrix microneedles;  chloasma;  effi cacy; safety
分类号:
R758.4+2
文献标志码:
A
摘要:
[摘要]目的：探讨低能量Q开关Nd:YAG激光联合点阵微针射频治疗黄褐斑的有效性和安全性。方法：本研究选取2016年2
月-2019年2月在笔者医院皮肤科就诊的黄褐斑114例患者，随机分为观察组（n =56）和对照组（n =58）。观察组：接受低能
量Q开关Nd:YAG激光联合点阵微针射频治疗；对照组：仅接受低能量Q开关Nd:YAG激光治疗。观察组激光治疗后1个月，进行
点阵微针射频第2次治疗，以此循环，各治疗3次为1个疗程；对照组仅接受Q开关1 064nm Nd:YAG激光治疗，1个月1次，共6
次为1个疗程。采用改良的黄褐斑面积及严重程度评分（Modified melasma area and severity index，mMASI）和医生整
体评价法(Physician global assessment, PGA)评价治疗前和末次治疗3个月后的效果，记录和比较两组患者的治疗不良反
应。 结果：与对照组比较，观察组mMASI的中位数下降分数明显高于对照组（2.9 vs 1.8，P ＜0.05），PGA评分优于“好”
的比例明显高于对照组（68% vs 54%，P＜0.05）。两组患者的治疗不良反应发生率无明显差异（P ＞0.05）。对照组的点状
色素减退和反弹性色素沉着的发生率较高。结论：对于亚洲人群黄褐斑患者，低能量Q开关Nd:YAG激光联合点阵微针射频治
疗临床效果好，安全性高。
Abstract:
Abstract: Objective To investigate the efficacy and safety of low-energy Q-switched Nd:YAG laser combined with lattice
micro needle radiofrequency in the treatment of chloasma. Methods A total of 114 patients with chloasma who were admitted
to our dermatology clinic from February 2016 to February 2019 were enrolled in the study. They were randomly divided into
observation group (n =56) and control group (n =58).The observation group received low-energy Q-switched Nd:YAG laser
combined with fractional microneedle radiofrequency treatment,the control group received only low-energy Q-switched
Nd:YAG laser treatment.A total of 10 times,2 treatment intervals of 1 week. The modifi ed Melasma Area and Severity Index
(mMASI) and the Physician Global Assessment (PGA) were used to evaluate the effects of pre-treatment and last treatment for
3 months.The adverse effects of treatment were recorded and compared between the two groups of patients. Results Compared
with the control group,the observation group showed better effi cacy. The median decline score of mMASI in the observation
group was signifi cantly higher than that in the control group (2.9 vs 1.8, P ＜0.05), and the PGA score was better than the “good”
group (68% vs 54%,P ＜0.05). There was no signifi cant difference in the incidence of adverse drug reactions between the two
groups (P ＞0.05). The incidence of punctate hypopigmentation and rebound pigmentation was higher in the control group.
Conclusion For Asian patients with chloasma, low-energy Q-switched Nd: YAG laser combined with lattice micro needle RF
has good clinical effect and high safety.

相似文献/References:

[1]钟 欣,郑 罡,丁 敏,等. 聚桂醇联合Nd:YAG激光治疗婴幼儿混合型血管瘤疗效评价[J].中国美容医学,2019,(01):55.
　ZHONG Xin,ZHENG Gang,DING Min,et al. Analysis of the Therapeutic Effects of Lauromacrogol Combined with Nd:YAG Laserin the Treatment of Infantile Mixed Hemangioma[J].Medical Aesthetics and Beauty,2019,(7):55.
[2]汪城河,苏晓灵,苏振民,等. 激光治疗婴幼儿浅表性血管瘤的疗效及并发症分析[J].中国美容医学,2019,(02):56.
　WANG Cheng-he,SU Xiao-ling,SU Zhen-min,et al. Clinical Analysis of the Effect and Complication of Laser Therapy for InfantileSuperficial Hemangioma[J].Medical Aesthetics and Beauty,2019,(7):56.
[3]张嘉文 刘子菁 王小燕 Juliandri刘韵祎 马仁燕 综述,许 阳 审校. 玫瑰痤疮的光电治疗研究进展[J].中国美容医学,2019,(05):159.
　ZHANG Jia-wen,LIU Zi-jing,WANG Xiao-yan,et al. Research Progress of Photoelectric for Rosacea[J].Medical Aesthetics and Beauty,2019,(7):159.
[4]林尤群,陈尧卉,李鹏程.Nd:YAG激光联合美白胶治疗氟斑牙临床效果分析[J].中国美容医学,2019,(06):112.
　LIN You-qun,CHEN Yao-hui,LI Peng-cheng. Clinical Analysis of Nd:YAG Laser Combined with Whitening Gel in the Treatment of Dental Fluorosis[J].Medical Aesthetics and Beauty,2019,(7):112.
[5]朱雅琳,聂 晶,帕丽达·阿布利孜. 强脉冲光与长脉宽Nd:YAG激光对婴幼儿血管瘤内皮细胞活性的影响[J].中国美容医学,2019,(09):96.
　ZHU Ya-lin,NIE Jing,Palidae·ABULIZ. Effects of Intense Pulsed Light and Long Pulse Width Nd:YAG Laser on EndothelialCell Activity in Infantile Hemangioma[J].Medical Aesthetics and Beauty,2019,(7):96.
[6] 陈 红,李 媚,王利娜,等. 口服普萘洛尔联合Nd:YAG激光治疗婴幼儿血管瘤的美容效果分析[J].中国美容医学,2021,(10):89.
　 CHEN Hong,LI Mei,WANG Li-na,et al. Cosmetic Effect of Oral Propranolol Combined with Nd:YAG Laser in the Treatmentof Infantile Hemangioma[J].Medical Aesthetics and Beauty,2021,(7):89.
[7]梁春霞,连 石,冉从华,等.长脉宽1 064nm Nd:YAG激光与2 940nm点阵激光联合外用类人胶原蛋白治疗眶周静态纹疗效观察[J].中国美容医学,2021,(12):71.
　LIANG Chun-xia,LIAN Shi,RAN Cong-hua,et al.Observation on Clinical Efficacy of Long-pulse 1 064nm Nd:YAG Laser and 2 940nm Fractional Laser Combined with Human-like Collagen in Treatment of Periorbital Static Wrinkles[J].Medical Aesthetics and Beauty,2021,(7):71.
[8]宋明宇,林 江,乔丽艳,等.3M FiltekTM Z350 XT 纳米树脂联合Nd:YAG激光填充楔状缺损疗效观察[J].中国美容医学,2021,(12):140.
　SONG Ming-yu,LIN Jiang,QIAO Li-yan,et al.Effect of 3M FiltekTM Z350 XT Nano-resin Combined with Nd:YAG Laser Filling Wedge Defect[J].Medical Aesthetics and Beauty,2021,(7):140.

更新日期/Last Update: 2020-07-22