[1]王鹏程,马国安,张 鑫.点阵CO2激光联合超声导入表皮生长因子治疗痤疮瘢痕效果分析[J].中国美容医学,2022,(2):70-73.
　WANG Pengcheng,MA Guoan,ZHANG Xin.Analysis of Effect of Dot Matrix CO2 Laser Combined with Epidermal Growth Factor Introduced by Ultrasound in the Treatment of Acne Scar[J].Medical Aesthetics and Beauty,2022,(2):70-73.
点击复制

点阵CO2激光联合超声导入表皮生长因子治疗痤疮瘢痕效果分析()
分享到：

《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2022年2期
页码:
70-73
栏目:
出版日期:
2022-02-10

文章信息/Info

Title:
Analysis of Effect of Dot Matrix CO2 Laser Combined with Epidermal Growth Factor Introduced by Ultrasound in the Treatment of Acne Scar
文章编号:
1008-6455（2022）02-0070-04
作者:
王鹏程; 马国安; 张 鑫
(衡水市人民医院皮肤科 河北 衡水 053000 )
Author(s):
WANG Pengcheng;  MA Guoan;  ZHANG Xin
(Department of Dermatology,Hengshui People’s Hospital,Hengshui 053000,Hebei,China)
关键词:
痤疮瘢痕; 点阵CO2激光; 超声; 表皮生长因子; 皮肤生理
Keywords:
acne scar;  dot matrix CO2 laser;  ultrasound;  epidermal growth factor;  physiological index of skin
分类号:
R622
文献标志码:
A
摘要:
目的：分析点阵CO2激光联合超声导入表皮生长因子治疗痤疮瘢痕的效果。方法：选择2019年1月-2020年2月笔者医院皮肤科收治的80例痤疮瘢痕患者为研究对象，采用随机数字表法分为对照组和观察组，每组40例。对照组采用点阵CO2激光治疗，观察组在对照组的基础上采用超声导入表皮生长因子凝胶治疗，两组均治疗6个月。比较两组治疗前和治疗后皮肤生理指标和疾病相关评分，观察两组治疗期间疾病相关指标和治疗后的临床疗效。结果：与治疗前比较，治疗后两组经皮水分丢失量、角质层蛋白质、乳酸刺激实验评分、皮肤屏障及痤疮瘢痕权重（ECCA）评分、皮肤黑素指数含量均降低，且观察组低于对照组，差异有统计学意义（P＜0.05）。与治疗前比较，治疗后两组角质层含水量升高，观察组高于对照组，差异有统计学意义（P＜0.05）。观察组结痂时间、红斑持续时间、误工期短于对照组，差异有统计学意义（P＜0.05）。治疗后，观察组总有效率为92.50%，显著高于对照组的75.00%，差异有统计学意义（P＜0.05）。结论：点阵CO2激光联合超声导入表皮生长因子治疗痤疮瘢痕，可有效改善患者皮肤生理功能，改善瘢痕程度，同时改善患者皮肤敏感度和黑色素情况，促进病情快速好转，具有良好的治疗效果。
Abstract:
Objective To analyze the effect of dot matrix CO 2 laser combined with epidermal growth factor introduced by ultrasound in the treatment of acne scar. Methods A total of 80 cases of acne scar patients admitted to the dermatology department of our hospital from January 2019 to February 2020 were selected as study subjects, and they were divided into the control group and the observation group by random number table method, with 40 cases in each group. The control group was treated with dot matrix CO2 laser, and the observation group was treated with epidermal growth factor introduced by ultrasound on the basis of the control group. Both groups were treated for 6 months. The skin physiological indicators and disease related scores of the two groups were compared before treatment and after the treatment, and the disease related indicators during treatment and clinical efficacy after the treatment of the two groups were observed. Results Compared with before treatment, the amount of percutaneous water loss, cuticle protein, lactic acid stimulation test score, skin barrier and acne scar weight (ECCA) score and dermal melanin in the two groups decreased after the treatment, and the observation group was lower than the control group (P<0.05). Compared with before treatment, the cuticle water content of the two groups increased after the treatment, and the observation group was higher than the control group (P＜0.05). The scab duration, erythema duration, and missed time period were shorter in the observation group than in the control groupp (P＜0.05). After the treatment, the total effective rate of treatment in the observation group was 92.50%, significantly higher than that in the control group (75.00%, P＜0.05). Conclusion Using dot matrix CO 2 laser combined with epidermal growth factor introduced by ultrasound to treat acne scar patients could effectively improve the skin physiological function of patients, improve the degree of scar, improve the patient’s skin sensitivity and melanin, promote the rapid improvement of the condition, with a good therapeutic effect.

相似文献/References:

[1]卢 可,葛红梅,李平松. CO2点阵激光联合A型肉毒毒素透皮给药技术治疗面部痤疮瘢痕临床观察[J].中国美容医学,2018,(08):112.
　LU Ke,GE Hong-mei,LI Ping-song. Clinical Effect and Safety Observation of Fractional Ultra-Pulsed CO2 Laser Combined with Transdermal Delivery of Botulinum Toxin A in the Treatment of Acne Scars[J].Medical Aesthetics and Beauty,2018,(2):112.
[2]肖杰华,黄咏梅. 自体富血小板血浆联合点阵铒激光治疗面部痤疮及痤疮瘢痕疗效观察[J].中国美容医学,2019,(02):60.
　XIAO Jie-hua,HUANG Yong-mei. Clinical Efficacy of Autologous Platelet-rich Plasma Combined with Dot Array Laserin the Treatment of Acne and Acne Scar on Face[J].Medical Aesthetics and Beauty,2019,(2):60.
[3]陈永平,王金河. 点阵铒激光联合羟基乙酸治疗面部痤疮瘢痕临床观察[J].中国美容医学,2019,(06):56.
　CHEN Yong-ping,WANG Jin-he. Clinical Efficacy of Combined Lattice Erbium Laser with Glycolic Acid Treatment of Facial Acne Scar[J].Medical Aesthetics and Beauty,2019,(2):56.
[4]胡 尧,李 凯,钱 运,等. 脉冲CO2点阵激光结合E光治疗痤疮瘢痕疗效分析[J].中国美容医学,2019,(07):41.
　HU Yao,LI Kai,QIAN Yun,et al. Therapeutic Effect of Pulsed CO2 Lattice Laser Combined with E-ray on Acne Scar[J].Medical Aesthetics and Beauty,2019,(2):41.
[5]颜 建,惠 慧,张 清. 群组看病及中医养生教育对痤疮瘢痕患者激光疗效及遵医行为的影响[J].中国美容医学,2020,(3):146.
　YAN Jian,HUI Hui,ZHANG Qing. Effect of Group Medical Treatment and TCM Health Education on the Curative Effectand Compliance Behavior of Patients with Acne Scar Laser Treatment[J].Medical Aesthetics and Beauty,2020,(2):146.
[6] 吕 君,周发琼,王元丰,等. 二氧化碳点阵激光联合胶原贴敷料对凹陷性痤疮瘢痕患者皮肤屏障及ECCA权重评分的影响[J].中国美容医学,2020,(5):23.
　 Effect of Carbon Dioxide Lattice Laser Combine with Collagen Dressing on SkinBarrier and ECCA Weight Score on Patients with Depressed Acne Scar[J].Medical Aesthetics and Beauty,2020,(2):23.
[7] 李芙蓉,刘晓雪,王 凯. 胶原贴敷料在激光治疗痤疮瘢痕后创面修复中的应用[J].中国美容医学,2020,(11):157.
　 LI Fu-rong,LIU Xiao-xue,WANG Kai. Application of Collagen Dressing in Wound Repair after Laser Treatment ofAcne Scar[J].Medical Aesthetics and Beauty,2020,(2):157.
[8] 黄艳丽,钱丽洁,陈凤娟,等. 点阵射频联合重组牛碱性成纤维细胞生长因子外用凝胶治疗痤疮凹陷性瘢痕临床观察[J].中国美容医学,2021,(5):94.
　 HUANG Yan-li,QIAN Li-jie,CHEN Feng-juan,et al. Clinical Observation on the Treatment of Atrophic Acne Scar with Dot MatrixRadiofrequency Combined and Recombinant Bovine Basic Fibroblast Growth Factor[J].Medical Aesthetics and Beauty,2021,(2):94.
[9] 刘玉东,李秀丽. 米诺环素结合复方黄柏液涂剂湿敷对寻常痤疮患者症状改善及皮损修复的效果研究[J].中国美容医学,2021,(7):61.
　 LIU Yu-dong,LI Xiu-li. Effects of Minocycline Combined with Compound Huangbai Epithem on Symptoms,Skin Lesions and Acne Scars Score in Acne Patients[J].Medical Aesthetics and Beauty,2021,(2):61.
[10] 王素玲,郝国栋,李冬静,等. 点阵CO2激光联合异维A酸治疗寻常痤疮疗效分析[J].中国美容医学,2021,(8):79.
　 WANG Su-ling,HAO Guo-dong,LI Dong-jing,et al. Analysis of the Therapeutic Effect of Fractional CO2 Laser Combined with Isotretinoinon Patients with Acne Vulgaris[J].Medical Aesthetics and Beauty,2021,(2):79.

更新日期/Last Update: 2022-03-07