[1]贾文斌 综述,谭 谦 审校.病理性瘢痕的非手术治疗新进展[J].中国美容医学,2023,(1):183-189.
 JIA Wenbin,TAN Qian.New Progress in Non-surgical Treatment of Pathological Scar[J].Medical Aesthetics and Beauty,2023,(1):183-189.
点击复制

病理性瘢痕的非手术治疗新进展()
分享到:

《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2023年1期
页码:
183-189
栏目:
出版日期:
2023-01-15

文章信息/Info

Title:
New Progress in Non-surgical Treatment of Pathological Scar
文章编号:
1008-6455(2023)01-0183-06
作者:
贾文斌 综述谭 谦 审校
(南京大学医学院 南京大学医学院附属鼓楼医院烧伤整形外科 江苏 南京 210008)
Author(s):
JIA WenbinTAN Qian
(Department of Burn Plastic Surgery, Medical College of Nanjing University,Nanjing Drum Tower Hospital,the Affi liated Hospital of Nanjing University Medical School,Nanjing 210008,Jiangsu,China)
关键词:
病理性瘢痕增生性瘢痕瘢痕疙瘩非手术治疗成纤维细胞
Keywords:
pathological scar hypertrophic scar keloids non-surgical treatment fi broblasts
分类号:
R619+ .6
文献标志码:
A
摘要:
病理性瘢痕是创伤后真皮成纤维细胞过度增殖而形成的良性病变,常见致病因素包括外伤、手术、烧伤、痤疮及皮肤 感染等,目前其发病机制以成纤维细胞过度增殖、胶原过度沉积且排列紊乱为主。病理性瘢痕的治疗主要分为手术和非手术 治疗,其中非手术治疗以其操作简单,创伤较小等优势被长期广泛应用于临床。除了压迫疗法、硅酮凝胶外用、药物和放 射治疗等方法外,干细胞与自体脂肪移植、A型肉毒毒素注射、细胞因子治疗、激光及射频等新型疗法目前也已被广泛应 用于瘢痕的非手术治疗和研究中。本文拟就目前瘢痕非手术治疗的国内外进展进行综述,并探讨新型治疗方法的优势及应用 前景。
Abstract:
Pathological scar is a benign disease caused by excessive proliferation of dermal fibroblasts after injury,and its common pathogenic factors include trauma,surgery,burn,acne,skin infection,etc.The current pathogenesis is dominated by excessive proliferation of fi broblasts,excessive deposition and disorder of collagen.The treatment of pathological scar is mainly divided into surgical and non-surgical treatment,among which non-surgical treatment has been widely used in clinical practice for a long time due to its advantages of simple operation and less trauma.In addition to compression therapy,silicone gel topical application,drug and radiation therapy,emerging non-surgical treatment methods such as stem cells and autologous fat transplantation,botulinum toxin type A injection,cytokine therapy,laser,radio frequency and so on have been widely used in the non-surgical treatment and research of scar.This article reviews the recent advances in non-surgical treatment of scar at home and abroad,and discusses the advantages and future application prospects of new treatment methods.

相似文献/References:

[1]陈 方. 咪喹莫特调节Th1、Th2细胞相关趋化因子对兔耳增生性瘢痕创面愈合和瘢痕增生的影响[J].中国美容医学,2018,(03):100.
 CHEN Fang. Effect of Imiquimod Regulating Th1 and Th2 Cell-associated Chemokines on Wound Healing and Scar Proliferation in Rabbits[J].Medical Aesthetics and Beauty,2018,(1):100.
[2]杨欣欣 综述,吴信峰 审校.A型肉毒毒素防治病理性瘢痕的研究进展[J].中国美容医学,2018,(05):150.
 YANG Xin-xin,WU Xin-feng.Progress of Botulinum Toxin Type A on Pathological Scar[J].Medical Aesthetics and Beauty,2018,(1):150.
[3]黄显翔,张 伟,叶光荣,等. CO2点阵激光治疗增生性瘢痕的临床疗效及对TGF-β1表达的影响[J].中国美容医学,2018,(08):108.
 HUANG Xian-xiang,ZHANG Wei,YE Guang-rong,et al.Analysis of the Clinical Effects and Influence on Expression of TGF-β1 of CO2 Lattice Laser in the Treatment of Hypertrophic Scar[J].Medical Aesthetics and Beauty,2018,(1):108.
[4]谢 彬. 深度烧伤患者弹力绷带压力治疗对增生性瘢痕恢复情况的影响[J].中国美容医学,2018,(10):62.
 XIE Bin. Effect of Pressure Treatment with Elastic Bandage on Recovery of Hypertrophic Scar in Patients with Deep Burn[J].Medical Aesthetics and Beauty,2018,(1):62.
[5]俞 舜. 微等离子体射频联合曲安奈德超声导入治疗增生性瘢痕疗效分析[J].中国美容医学,2019,(02):63.
 YU Shun. Clinical Study on Microplasma Radiofrequency Combined with Ultrasonic ImportingTriamcinolone Acetonide in the Treatment of Hypertrophic Scar[J].Medical Aesthetics and Beauty,2019,(1):63.
[6]史 敏,李 娜,郭晓波,等.miR-21调控PTEN/PI3K/Akt通路抑制增生性瘢痕形成的机制研究[J].中国美容医学,2019,(03):92.
 SHI Min,LI Na,GUO Xiao-bo,et al. Mechanism of miR-21 Inhibiting Human Hypertrophic Scar Formation by RegulatingPTEN/PI3K/Akt Pathway[J].Medical Aesthetics and Beauty,2019,(1):92.
[7]李 丽,王 林. 正常皮肤与病理性瘢痕组织中HIF-1α和促炎细胞因子水平比较及两者相关性研究[J].中国美容医学,2019,(04):71.
 LI Li,WANG Lin. Levels of HIF-1α and Proinflammatory Cytokines in Normal Skin and PathologicalScar Tissue and Their Correlation[J].Medical Aesthetics and Beauty,2019,(1):71.
[8]史 敏 李 娜 陈 雷 刘兆旺 魏超鹏综述,封兴华审校. 自噬、miRNA与增生性瘢痕的研究进展[J].中国美容医学,2019,(04):160.
 SHI Min,LI Na,CHEN Lei,et al. Advance in Research on Autophagy, miRNA and Hypertrophic Scar[J].Medical Aesthetics and Beauty,2019,(1):160.
[9]龙彦岑 陈先卓 贺译贤 赵鹏宇 刘小嘉 综述,向小燕 审校. 自噬在病理性瘢痕形成中的作用及其相关研究进展[J].中国美容医学,2019,(06):168.
 LONG Yan-cen,CHEN Xian-zhuo,HE Yi-xian,et al. Advances in the Role of Autophagy In Pathologic Scar Formation[J].Medical Aesthetics and Beauty,2019,(1):168.
[10]吴志贤,李 响,莫自增,等. 异泽兰黄素通过PDGFβ/ERK信号通路抑制增生性瘢痕生长的机制探讨[J].中国美容医学,2019,(07):44.
 WU Zhi-xian,LI Xiang,MO Zi-zeng,et al.Eupatilin Inhibits Hypertrophic Scar Proliferation Via the PDGFβ/ERK Signaling Pathway[J].Medical Aesthetics and Beauty,2019,(1):44.
[11]毛姝然 综述,肖志波 审校.病理性瘢痕的治疗现状及研究进展[J].中国美容医学,2022,(1):181.
 MAO Shuran,XIAO Zhibo.Treatment Status and Research Progress of Pathologic Scars[J].Medical Aesthetics and Beauty,2022,(1):181.
[12]李程丽,欧阳华伟.曲安奈德局部注射治疗儿童病理性瘢痕的单组率Meta分析[J].中国美容医学,2023,(1):102.
 LI Chengli,OUYANG Huawei.A Single-group Rate Meta-analysis of Local Injection of Triamcinolone Acetonide in the Treatment of Children with Pathological Scars[J].Medical Aesthetics and Beauty,2023,(1):102.
[13]胡智瀚 王铄链 崔振芸 综述,刘 毅 审校.病理性瘢痕的注射治疗进展[J].中国美容医学,2024,(1):191.
 HU Zhihan,WANG Shuolian,CUI Zhenyun,et al.Progress in the Treatment of Pathological Scars by Injection Therapy[J].Medical Aesthetics and Beauty,2024,(1):191.

更新日期/Last Update: 2023-02-02